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Antibody Screening and Characterization
Antibody Screening and Characterization

Antibody Screening and Characterization

Generating an antibody with dependable, predictable, and most importantly, intended performance is a long process that doesn't end with purification or even clonal selection. In order to understand and anticipate how your antibody will perform and interact in your application, antibody screening and characterization is fundamental.

In the context of Therapeutic Antibody Drug Discovery, screening and characterization is even more critical. From isotyping through affinity ranking, screening and characterizing monoclonal antibodies lays the groundwork for rational selection of lead candidates. GenScript's years of expertise and propriety high throughput technologies allow us to offer a suite of services covering all characterization and screening requirements. Best of all these services easily and seamlessly integrate with our custom antibody generation services. In less than 1 week we can screen and characterize antibody drug lead candidates, revealing their essential attributes as follows.

Key Antibody Characterizations

GenScript's Proprietary Technology for Antibody Screening and Characterization

Our team of antibody development scientists have created a repertoire of proprietary screening technologies capable of fast and accurate antibody screening and characterization. Our technologies summarized below combine EC50 & IC50 measurements, epitope binning, ligand blocking capabilities, and cross reactivity in high-throughput formats to rationally select antibodies most suited to your goals.

GenScript'sScreening Technology Assay Details
Superdoma™
Epitope binning & relative affinity ranking to identify functional clones in earliest stage of hybridoma development.
NativeSelect™
High throughput antibody binding via capture ELISA screening of soluble targets, maintaining antigen conformation and avoiding epitope masking.
HT March™
Antibody binding via cell-based fluorometric microvolume assay technology (FMAT) provides high throughput screening of membrane bound targets.

Antibody Screening and Characterization Related Services

GenScript provides a suite of antibody services including Therapeutic Antibody Drug Discovery Services, catering to every step in the process from lead generation, to optimization, and finally production at any scale. A few of our industry leading services include:

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Antibody Screening and Characterization

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Antibody Screening and Characterization

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