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ABCA1 Antibody, mAb, Mouse

*This product has been discontinued!*
This membrane-associated protein is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extracellular and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. This protein functions as a cholesteral efflux pump in the cellular lipid removal pathway. Mutations in this gene have been associated with Tangiers disease and familial high-density lipoprotein deficiency.
A00121
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Specificity Recognize specifically ABCA1 from human, mouse, and chicken
Host Species Mouse
Immunogen Recombinant fragment, corresponding to amino acids 1800-2260 of Human ABCA1
Species Reactivity Human, mouse, and chicken
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Concentration 1 mg/ml in PBS, pH 7.4 with 0.05% sodium azide, frozen liquid
Purification Immunoaffinity purification
Clone ID A00121.01
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Target Background This membrane-associated protein is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extracellular and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. This protein functions as a cholesteral efflux pump in the cellular lipid removal pathway. Mutations in this gene have been associated with Tangiers disease and familial high-density lipoprotein deficiency.
Synonyms Mouse Anti-ABCA1 mAb; Anti ABCA1
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