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Cat. No.
Name
Size   
Price
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A00819
40 μg
$55
Desmin Antibody, mAb, Mousecustom antibody production
Desmin Antibody, mAb, Mouse
Full Name Desmin Antibody, mAb, Mouse
Abbreviated name-1
Mouse Anti-Desmin mAb;
Documents
Desmin Antibody, mAb, MouseDocument-MSDS: 8239_20081114033338.PDF (PDF)
Desmin Antibody, mAb, MouseDocument-MSDS: NaN3 MSDS.pdf (pdf)
Figures
Desmin Antibody, mAb, Mouse zoomDesmin Antibody, mAb, Mouse
Desmin Antibody, mAb, Mouse zoomDesmin Antibody, mAb, Mouse
Citations
Description
Desmin (DES), with 470-amino acid protein (about 52,000 Da), belongs to the intermediate filament family and Desmin is class III intermediate filaments found in muscle cells. Homopolymers of Desmin form a stable intracytoplasmic filamentous network connecting myofibrils to each other and to the plasma membrane. Mutations in Desmin are associated with desmin-related myopathy, a familial cardiac and skeletal myopathy (CSM), and with distal myopathies. Desmin is also expressed in smooth muscle cells of both airways and alveolar ducts and Desmin is a load-bearing protein that stiffens the airways and consequently the lung and modulates airway contractile response.
Ig Subclass
IgG1
Storage
This product remains stable for one to two weeks if stored at 2°C to 8°C. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freezing and thawing cycles. Use before is one year from the date of receipt.
Specificity
Truncated Desmin recombinant protein (WB), human Desmin recombinant protein (ELISA), human smooth muscle sarcoma (IHC)
Concentration
1 mg/ml in 10 mM PBS (pH 7.6) and 0.02% sodium azide
Immunogen
Ni-NTA purified truncated recombinant Desmin expressed in E. coli strain BL21 (DE3)
Clone ID
A00819.01
Applications
Western blot:1:1,000-1:2,000
IHC(P):1:1,000-1:2,000
IHC(F): 1:1,000-1:2,000
ELISA: Propose dilution 1:10,000
Determining optimal working dilutions by titration test
Host Species
Mouse
Antigen Species
Human
Note
Briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container's cap because small volumes of antibody will occasionally become entrapped in the seal of the product vial during shipment and storage.
Technical Manual
ELISA Protocol (pdf)
Western Blot Protocol (pdf)
FACS Protocol (pdf)
IHC Protocol (pdf)
IP Protocol (pdf)
1
Antibody Services: GenScript's custom antibody service guarantees 1:32,000 ELISA titer of final product or two ELISA positive clones with the help of our advanced antigen design tool.
2
Polyclonal antibody Services: GenScript's custom polyclonal antibody services start from $250. It comes with a 1:32,000 ELISA titer guarantee, thanks to our advanced antigen design tool.
3
Custom Monoclonal Antibody Services: GenScript's custom monoclonal antibody service guarantees two ELISA positive clones with the help of advanced hybridoma technology & experienced professional.