Presenilin 1 Antibody, pAb, Rabbit
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A00881-40
40 μg
$99
Presenilin 1 Antibody, pAb, Rabbit
Full Name Presenilin 1 Antibody, pAb, Rabbit
Abbreviated name-1
Rabbit anti-PS1 pAb;
Documents
Presenilin 1 Antibody, pAb, RabbitDocument-MSDS: 8317_20081118035648.PDF (PDF)
Presenilin 1 Antibody, pAb, RabbitDocument-MSDS: Sodium_Azide_MSDS.pdf (pdf)
Figures
Presenilin 1 Antibody, pAb, Rabbit zoomPresenilin 1 Antibody, pAb, Rabbit
Ig Subclass
Rabbit IgG
Storage
The antibody is stable for 2-3 weeks if stored at 2-8°C. For long term storage, aliquot and store at -20°C or below. Avoid repeated freezing and thawing cycles.
Specificity
GenScript Rabbit Anti-Presenilin 1 Polyclonal Antibody can detect endogenous levels of the full-length protein (approx. 43-52 kD) and the N-terminal fragment of presenilin 1 (≈ 28 kD).
Formulation
0.5 mg/ml in PBS, pH 7.4, containing 30% glycerol, and 0.02% sodium azide
Immunogen
Synthetic peptide corresponding to amino acids 25-50 (TVRSQNDNRERQEHNDRRSLGHPEPL) of the N-terminus of human presenilin 1, which is exposed to the extracellular region, KLH conjugated.
Purification Method
Immunoaffinity chromatography
Applications
Working concentrations for specific applications should be determined by the investigator. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product.
ELISA: 0.05-0.2 µg/ml
Western blot: 0.5-2.0 µg/ml
Conjugation
Unconjugated
Species Reactivity
Human, mouse
Host Species
Rabbit
Antigen Species
Human
Note
Small volume of antibody will occasionally become entrapped in the cap of the vial during shipment and storage. Before use, centrifuge the vial briefly to bring down any liquid in the cap.
Technical Manual
ELISA Protocol (pdf)
Western Blot Protocol (pdf)
FACS Protocol (pdf)
IHC Protocol (pdf)
IP Protocol (pdf)
ELISA Protocol (pdf)
Western Blot Protocol (pdf)
FACS Protocol (pdf)
IHC Protocol (pdf)
IP Protocol (pdf)
ELISA Protocol (pdf)
Western Blot Protocol (pdf)
FACS Protocol (pdf)
IHC Protocol (pdf)
IP Protocol (pdf)
Document-COA
Citation
Okumura N.,et al. Genistein downregulates presenilin 1 and ubiquilin 1 expression.Mol Med Rep.2012Feb;5(2):559-61

Yoshida H.,et al. Turmeric and curcumin suppress presenilin 1 protein expression in Jurkat cells.Exp Ther Med.2011Apr;2(4):629-632

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