Superoxide Dismutase 1 Antibody, pAb, Rabbit

*This product has been discontinued!*

Superoxide Dismutase 1 (SwissProt P00441) is a major antioxidant enzyme that catalyzes the conversion of superoxide anion to hydrogen peroxide and molecular oxygen. SOD1 is ubiquitously expressed and is localized in the cytosol, nucleus, and mitochondrial intermembrane space. Defects in SOD1 are the cause of amyotrophic lateral sclerosis type 1 (ALS1).GenScript Rabbit Anti-Superoxide Dismutase 1 Polyclonal Antibody is developed in rabbit using a synthetic peptide of human Superoxide Dismutase 1.

Cat. No.	A01005
Size	Buy in bulk

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Overview Applications Properties Background

Overview

Specificity	GenScript Rabbit Anti-Superoxide Dismutase 1 Polyclonal Antibody can detect endogenous level of human superoxide dismutase 1. Sequence homology predicts that it will also react with mouse, rat, pig, horse, bovine, bornean orangutan, chimpanzee, and fission yeast superoxide dismutase 1.
Host Species	Rabbit
Immunogen	Synthetic peptide (KLH conjugated) of human superoxide dismutase 1

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Applications

Application	Recommended Usage
ELISA	0.03-1.0 µg/ml
Western Blot	1.0 µg/ml
Other applications	User-optimized

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Properties

Concentration	0.5 mg/ml in PBS, pH 7.4, containing 30% glycerol and 0.02% sodium azide
Purification	Immunoaffinity chromatography

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Background

Target Background

Superoxide Dismutase 1 (SwissProt P00441) is a major antioxidant enzyme that catalyzes the conversion of superoxide anion to hydrogen peroxide and molecular oxygen. SOD1 is ubiquitously expressed and is localized in the cytosol, nucleus, and mitochondrial intermembrane space. Defects in SOD1 are the cause of amyotrophic lateral sclerosis type 1 (ALS1).
GenScript Rabbit Anti-Superoxide Dismutase 1 Polyclonal Antibody is developed in rabbit using a synthetic peptide of human Superoxide Dismutase 1.

Synonyms

Rabbit Anti-Superoxide Dismutase 1 pAb;Rabbit Anti Superoxide dismutase [Cu-Zn] pAb;Rabbit Anti SOD1 pAb;

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Citations

1. NJ Dawson, et al. Free-radical first responders: The characterization of CuZnSOD and MnSOD regulation during freezing of the freeze-tolerant North American wood frog, Rana sylvatica. Biochim Biophys Acta. (2014-10)