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TRF1 Antibody, pAb, Rabbit

Cat. No.	Name	Size	Price
A01198-200	TRF1 Antibody, pAb, Rabbit	200 μg(5x40μg)	$225
A01198-40	TRF1 Antibody, pAb, Rabbit	40 μg	$50

Full Name

TRF1 Antibody, pAb, Rabbit

Abbreviated name-1

Rabbit Anti-TRF1 pAb;

Documents
Document-MSDS: 8947_20081214205458.PDF (PDF)
Document-MSDS: 3739_20080118034804.PDF (PDF)
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Reference

Description

TRF1 is a telomere-specific protein that contains a C-terminal Myb motif. It has a dimerization domain near its acidic N-terminus. It binds to the telomeric double-stranded TTAGGG repeat and negatively regulates telomere length. TRF1 is also involved in mitotic spindle regulation.
GenScript Rabbit Anti-TRF1 Polyclonal Antibody is developed in rabbit hosts using a KLH-coupled synthetic peptide within residues 70-120 of human TRF1 protein (Swiss Prot: P54274).

Ig Subclass

Rabbit IgG

Storage

The antibody is stable in lyophilized form if stored at -20°C or below. The reconstituted antibody can be stored for 2-3 weeks at 2-8°C. For long term storage, aliquot and store at -20°C or below. Avoid repeated freezing and thawing cycles.

Specificity

GenScript Rabbit Anti-TRF1 Polyclonal Antibody detects human TRF1 protein. Sequence homology predicts that it will also react with mouse TRF1 protein.

Concentration

0.5 mg/ml, lyophilized with PBS, pH 7.4, containing 0.02% sodium azide

Immunogen

Synthetic peptide (KLH-coupled) within residues 70-120 of human TRF1 protein (Swiss Prot: P54274)

Purification Method

Immunoaffinity chromatography

Reconstitution

Reconstitute the lyophilized powder with deionized water (or equivalent) to an antibody concentration of 0.5 mg/ml.

Predicted Band Size

50 kD

Applications

Working concentrations for specific applications should be determined by the investigator. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product.
ELISA: 0.05-0.2 µg/ml
Western blot: 0.5-1 µg/ml
Other applications: user-optimized

Conjugation

Unconjugated

Species Reactivity

Human. This product has not yet been tested with other species.

Host Species

Rabbit

Antigen Species

Human

Note

Small volumes of antibody will occasionally become trapped in the seal of the product vial during shipment and storage. Before use, briefly centrifuge the vial to dislodge any liquid in the container's cap.

Technical Manual

TM0589.pdf (PDF)
TM0590.pdf (PDF)
TM0591.pdf (PDF)
TM0592.pdf (PDF)
TM0593.pdf (PDF)


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