You are here: Products » Antibodies » Primary Antibodies » Phospho-Specific Antibodies » antibody : Rabbit Anti-Caspr2 Polyclonal Antibody

Caspr2 Antibody, pAb, Rabbit

Cat. No.	Name	Size	Price
A01426-200	Caspr2 Antibody, pAb, Rabbit	200 μg(5x40μg)	$225
A01426-40	Caspr2 Antibody, pAb, Rabbit	40 μg	$50

Full Name

Caspr2 Antibody, pAb, Rabbit

Abbreviated name-1

Contacting-associated protein 2 antibody;

Documents
Document-MSDS: 10270_20090724060849.PDF (PDF)
Figures
zoom
Reference

Description

Contacting-associated protein 2 (Caspr2) is a member of the neurexin superfamily that mediates nervous system cell-cell interactions. The C-terminal region of Caspr2 participates in the association with Kv1.1, Kv1.2 and their Kv-beta-2 subunit. Expression of Caspr2 is regulated directly by transcription factor FOXP2. Disruption or decreased expression of Caspr2 probably leads to a disturbed distribution of potassium channels in the nervous system. Mutations in the Caspr2 gene have been linked to many diseases such as focal epilepsy, autism spectrum disorder and cortical dysplasia-focal epilepsy syndrome (CDFES).

GenScript Rabbit Anti-Caspr2 Polyclonal Antibody is developed in rabbit using a KLH-coupled synthetic peptide from C-terminal of human Caspr2 (Swiss Prot: Q9UHC6).

Ig Subclass

Rabbit IgG

Storage

The antibody is stable in lyophilized form if stored at -20°C or below. The reconstituted antibody can be stored for 2-3 weeks at 2-8°C. For long term storage, aliquot and store at -20°C or below. Avoid repeated freezing and thawing cycles.

Specificity

GenScript Rabbit Anti-Caspr2 Polyclonal Antibody detects endogenous levels of mouse and rat Caspr2. It is predicted to react with human Caspr2 according to sequence homology.
Positive Control: mouse brain and rat brain.

Concentration

0.5 mg/ml, lyophilized with PBS, pH 7.4, containing 0.02% sodium azide.

Immunogen

KLH-coupled synthetic peptide from C-terminal of human Caspr2 (Swiss Prot: Q9UHC6)

Purification Method

Immunoaffinity chromatography

Reconstitution

Reconstitute the lyophilized powder with deionized water (or equivalent) to an antibody concentration of 0.5 mg/ml.

Applications

Working concentrations for specific applications should be determined by the investigator. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product.
Western blot: 0.5-1 µg/ml
Other Applications: user-optimized

Conjugation

Unconjugated

Species Reactivity

Mouse and rat. This product has not been tested for other species yet.

Host Species

Rabbit

Antigen Species

Human

Technical Manual

TM0589.pdf (PDF)
TM0590.pdf (PDF)
TM0591.pdf (PDF)
TM0592.pdf (PDF)
TM0593.pdf (PDF)


1	Antibody Services: GenScript's custom antibody service guarantees 1:32,000 ELISA titer of final product or two ELISA positive clones with the help of our advanced antigen design tool.
2	Polyclonal antibody Services: GenScript's custom polyclonal antibody services start from $250. It comes with a 1:32,000 ELISA titer guarantee, thanks to our advanced antigen design tool.
3	Custom Monoclonal Antibody Services: GenScript's custom monoclonal antibody service guarantees two ELISA positive clones with the help of advanced hybridoma technology & experienced professional.