OLIG2 Antibody, pAb, Rabbit

*This product has been discontinued!*

OLIG2 (oligodendrocyte lineage transcription factor 2) is basic helix-loop-helix transcription factor. It is expressed exclusively in oligodendrocytes and oligodendrocyte precursors. OLIG2 plays independent roles in specifying the fates of motoneuron and oligodendrocyte. It is necessary for oligodendrocyte and motor neuron specification in the spinal cord. In addition, OLIG2 serves as a repressor of neurogenesis in cells reacting to brain injury.GenScript Rabbit Anti-OLIG2 Polyclonal Antibody is developed in rabbit using a KLH-coupled synthetic peptide within residues 50-100 of human OLIG2 (Swiss Prot: Q13516).

Cat. No.	A01474
Size	Buy in bulk

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Overview Properties Background

Overview

Specificity	GenScript Rabbit Anti-OLIG2 Polyclonal Antibody detects endogenous levels of human, mouse, and rat OLIG2. Positive control:SH-SY5Y cell, mouse brain,and rat brain.
Host Species	Rabbit
Immunogen	KLH-coupled synthetic peptide within residues 50-100 of human OLIG2 (Swiss Prot: Q13516).
Species Reactivity	Human, mouse, and rat. This product has not been tested with other species yet.

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Properties

Concentration	0.5 mg/ml, lyophilized with PBS, pH 7.4, containing 0.02% sodium azide
Reconstitution	Reconstitute the lyophilized powder with deionized water (or equivalent) to an antibody concentration of 0.5 mg/ml.
Purification	Immunoaffinity chromatography

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Background

Target Background

OLIG2 (oligodendrocyte lineage transcription factor 2) is basic helix-loop-helix transcription factor. It is expressed exclusively in oligodendrocytes and oligodendrocyte precursors. OLIG2 plays independent roles in specifying the fates of motoneuron and oligodendrocyte. It is necessary for oligodendrocyte and motor neuron specification in the spinal cord. In addition, OLIG2 serves as a repressor of neurogenesis in cells reacting to brain injury.

GenScript Rabbit Anti-OLIG2 Polyclonal Antibody is developed in rabbit using a KLH-coupled synthetic peptide within residues 50-100 of human OLIG2 (Swiss Prot: Q13516).

Synonyms

Oligodendrocyte transcription factor 2 antibody;

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Citations

1. LaneRosemary, et al. Cell-derived extracellular vesicles can be used as a biomarker reservoir for glioblastoma tumor subtyping. Commun Biol. (2019)