Catalog Products » Antibodies » antibody : alpha 1 Glycine Receptor Antibody, pAb, Rabbit
Cat. No.
Name
Size   
Price
Selected
A01636-40
40 μg
$79 $47
A01636-100
100 μg
$198
alpha 1 Glycine Receptor Antibody, pAb, Rabbit
Full Name alpha 1 Glycine Receptor Antibody, pAb, Rabbit
Abbreviated name-1
GLRA1 Antibody, pAb, Rabbit;
Documents
alpha 1 Glycine Receptor Antibody, pAb, RabbitDocument-MSDS: 12354_20100330031239.PDF (PDF)
Figures
alpha 1 Glycine Receptor Antibody, pAb, Rabbit zoomalpha 1 Glycine Receptor Antibody, pAb, Rabbit
Description
The glycine receptor is a neurotransmitter-gated ion channel. Glycine is an important inhibitory transmitter in the brainstem and spinal cord. Binding of glycine to its receptor increases the chloride conductance and thus produces hyperpolarization. The alpha-1 subunit of the glycine receptor is a ligand-gated chloride channel. This inhibitory glycine receptor mediates postsynaptic inhibition in the spinal cord and other regions of the central nervous system. It is a pentameric receptor composed of alpha and beta subunits. Defects in alpha 1 Glycine Receptor are implicated in the pathophysiology of startle disease (STHE).
GenScript alpha 1 Glycine Receptor Antibody, pAb, Rabbit is developed in rabbit using a KLH-coupled synthetic peptide from N-terminal of human alpha 1 Glycine Receptor (Swiss Prot: P23415).
Ig Subclass
Rabbit IgG
Storage
The antibody is stable in lyophilized form if stored at -20°C or below. The reconstituted antibody can be stored for 2-3 weeks at 2-8°C. For long term storage, aliquot and store at -20°C or below. Avoid repeated freezing and thawing cycles.
Specificity
GenScript alpha 1 Glycine Receptor Antibody, pAb, Rabbit detects endogenous levels of mouse alpha 1 Glycine Receptor. It is predicted to react with human alpha 1 Glycine Receptor according to sequence homology.
Positive Control: Mouse brain
Formulation
0.5 mg/ml, lyophilized with PBS, pH 7.4, containing 0.02% sodium azide
Immunogen
KLH-coupled synthetic peptide from N-terminal of human alpha 1 Glycine Receptor (Swiss Prot: P23415)
Purification Method
Immunoaffinity chromatography
Reconstitution
Reconstitute the lyophilized powder with deionized water (or equivalent) to an antibody concentration of 0.5 mg/ml.
Predicted Band Size
52 KD
Observed Band Size
48 KD
Conjugation
Unconjugated
Species Reactivity
Mouse. Reactivity to other species is not tested yet.
Host Species
Rabbit
Antigen Species
Human
Technical Manual
ELISA Protocol (pdf)
Western Blot Protocol (pdf)
FACS Protocol (pdf)
IHC Protocol (pdf)
IP Protocol (pdf)
Document-COA
1
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