Catalog Products » Other Products » New Products » alpha 1 Glycine Receptor Antibody, pAb, Rabbit
Email to GenScript

alpha 1 Glycine Receptor Antibody, pAb, Rabbit


Select
Cat. No.
Product Name
Size
Price
Quantity
A01636-40 alpha 1 Glycine Receptor Antibody, pAb, Rabbit
40 μg
$99.00
A01636-100 alpha 1 Glycine Receptor Antibody, pAb, Rabbit
100 μg
$199.00



Abbreviated name-1 GLRA1 Antibody, pAb, Rabbit;
Description The glycine receptor is a neurotransmitter-gated ion channel. Glycine is an important inhibitory transmitter in the brainstem and spinal cord. Binding of glycine to its receptor increases the chloride conductance and thus produces hyperpolarization. The alpha-1 subunit of the glycine receptor is a ligand-gated chloride channel. This inhibitory glycine receptor mediates postsynaptic inhibition in the spinal cord and other regions of the central nervous system. It is a pentameric receptor composed of alpha and beta subunits. Defects in alpha 1 Glycine Receptor are implicated in the pathophysiology of startle disease (STHE).
GenScript alpha 1 Glycine Receptor Antibody, pAb, Rabbit is developed in rabbit using a KLH-coupled synthetic peptide from N-terminal of human alpha 1 Glycine Receptor (Swiss Prot: P23415).
Immunogen KLH-coupled synthetic peptide from N-terminal of human alpha 1 Glycine Receptor (Swiss Prot: P23415)
Host Species Rabbit
Conjugation Unconjugated
Purification Method Immunoaffinity chromatography

Formulation 0.5 mg/ml, lyophilized with PBS, pH 7.4, containing 0.02% sodium azide
Reconstitution Reconstitute the lyophilized powder with deionized water (or equivalent) to an antibody concentration of 0.5 mg/ml.
Ig Subclass Rabbit IgG
Specificity GenScript alpha 1 Glycine Receptor Antibody, pAb, Rabbit detects endogenous levels of mouse alpha 1 Glycine Receptor. It is predicted to react with human alpha 1 Glycine Receptor according to sequence homology.
Positive Control: Mouse brain
Storage The antibody is stable in lyophilized form if stored at -20°C or below. The reconstituted antibody can be stored for 2-3 weeks at 2-8°C. For long term storage, aliquot and store at -20°C or below. Avoid repeated freezing and thawing cycles.

Working concentrations for specific applications should be determined by the investigator. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product.
Western blot: 1-2 µg/ml
Immunohistochemistry: 5-10 µg/ml
Other Applications: user optimized
Technical Manual ELISA Protocol(pdf)
Western Blot Protocol(pdf)
FACS Protocol(pdf)
IHC Protocol(pdf)
IP Protocol(pdf)

Alpha 1 Glycine Receptor Antibody, PAb, Rabbit

Alpha 1 Glycine Receptor Antibody, PAb, Rabbit

Alpha 1 Glycine Receptor Antibody, PAb, Rabbit

Alpha 1 Glycine Receptor Antibody, PAb, Rabbit

Alpha 1 Glycine Receptor Antibody, PAb, Rabbit

Alpha 1 Glycine Receptor Antibody, PAb, Rabbit
Alpha 1 Glycine Receptor Antibody, PAb, Rabbit

Western blot analysis of tissue lysates using alpha 1 Glycine Receptor Antibody, pAb, Rabbit (GenScript, A01636, 1 µg/ml)
The signal was developed with IRDye™ 800 Conjugated Goat Anti-Rabbit IgG.
Predicted Size: 52 KD
Observed Size: 48 KD

Alpha 1 Glycine Receptor Antibody, PAb, Rabbit

Alpha 1 Glycine Receptor Antibody, PAb, Rabbit
Alpha 1 Glycine Receptor Antibody, PAb, Rabbit

Immunohistochemistry analysis of human brain, cortex tissue slide (Paraffin embedded) using alpha 1 Glycine Receptor Antibody, pAb, Rabbit (GenScript, Cat.No. A01636, 10 µg/ml)

Alpha 1 Glycine Receptor Antibody, PAb, Rabbit
Alpha 1 Glycine Receptor Antibody, PAb, Rabbit

Immunohistochemistry analysis of human testis tissue slide (Paraffin embedded) using alpha 1 Glycine Receptor Antibody, pAb, Rabbit (GenScript, Cat.No. A01636, 10 µg/ml)

Alpha 1 Glycine Receptor Antibody, PAb, Rabbit




Notice there is no results found, you can visit "Citations Database" for other results.






For more documents, please visit "Technical Support".