Sequence in raw or FASTA format:
GALC galactosylceramidase [Monodelphis domestica (gray short-tailed opossum)]
|Entrez Gene ID||100019857|
|General protein information||
|Organism||Monodelphis domestica (gray short-tailed opossum)|
What is the normal function of the GALC gene?
The GALC gene provides instructions for making an enzyme called galactosylceramidase. Through a process called hydrolysis, this enzyme uses water molecules to break down certain fats called galactolipids, which are found primarily in the brain and kidneys.
Within cells, galactosylceramidase is found in enzyme-filled sacs called lysosomes where it hydrolyzes specific galactolipids, including galactosylceramide and psychosine. Galactosylceramide is an important component of myelin, the protective covering around certain nerve cells that ensures the rapid transmission of nerve impulses. Psychosine forms during the production of myelin, and then it breaks down with help of galactosylceramidase. Under normal conditions, tissues contain very little psychosine.
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