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KCNE3 potassium voltage-gated channel, Isk-related family, member 3 [Homo sapiens (human)]


RefSeq Accession Definition Service Stock Status Price *Turnaround time Order
NM_005472 Homo sapiens potassium voltage-gated channel, Isk-related family, member 3 (KCNE3), mRNA. GenEZ ORF Cloning In-stock $248.00 $199.00 10

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Gene Symbol KCNE3
Entrez Gene ID 10008
Full Name potassium voltage-gated channel, Isk-related family, member 3
Synonyms HOKPP, HYPP, MiRP2
General protein information
Preferred Names
potassium voltage-gated channel subfamily E member 3
Names
potassium voltage-gated channel subfamily E member 3
minK-related peptide 2
potassium channel subunit beta MiRP2
voltage-gated K+ channel subunit MIRP2
minimum potassium ion channel-related peptide 2
cardiac voltage-gated potassium channel accessory subunit
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

11

11q13.4

Summary Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, isk-related subfamily. This member is a type I membrane protein, and a beta subunit that assembles with a potassium channel alpha-subunit to modulate the gating kinetics and enhance stability of the multimeric complex. This gene is prominently expressed in the kidney. A missense mutation in this gene is associated with hypokalemic periodic paralysis. [provided by RefSeq, Jul 2008].
Disorder

MIM: 604433

Brugada syndrome 6, 613119 (3)

mRNA Protein Product Sequence Price Select
NM_005472, 115387116 NP_005463, 4885443 potassium voltage-gated channel subfamily E member 3 ORF Sequence $99.00
KEGG
hsa04974Protein digestion and absorption
Homo sapiens (human)KCNE3NP_005463.1
Pan troglodytes (chimpanzee)KCNE3XP_003952024.1
Macaca mulatta (Rhesus monkey)LOC718902XP_001115704.2
Canis lupus familiaris (dog)KCNE3XP_005633571.1
Bos taurus (cattle)KCNE3XP_005201011.1
Mus musculus (house mouse)Kcne3NP_001177879.1
Rattus norvegicus (Norway rat)Kcne3NP_071571.1
Gallus gallus (chicken)KCNE3XP_425664.1
Xenopus (Silurana) tropicalis (western clawed frog)kcne3XP_002942498.2
Process
IDNameEvidence
GO:0034765regulation of ion transmembrane transportIEA
GO:0043266regulation of potassium ion transportIEA
GO:0071805potassium ion transmembrane transportIEA
Component
IDNameEvidence
GO:0016021integral component of membraneIEA
Function
IDNameEvidence
GO:0005249voltage-gated potassium channel activityIEA
GO:0015459potassium channel regulator activityIEA
GeneCards KCNE3
UniProt Q9Y6H6, Q6IAE6
Vega OTTHUMG00000165641
MIM 604433
Ensembl ENSG00000175538
HGNC 6243
HPRD 07256

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Interactant

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