This gene was identified by its induced expression in B
lymphocytes in response Epstein-Barr virus infection. It encodes a
secreted glycoprotein belonging to the hematopoietin receptor
family, and heterodimerizes with a 28 kDa protein to form
interleukin 27 (IL-27). IL-27 regulates T cell and inflammatory
responses, in part by activating the Jak/STAT pathway of CD4+ T
cells. [provided by RefSeq].