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EBI3 Epstein-Barr virus induced 3 [Homo sapiens (human)]


RefSeq Accession Definition Service Stock Status Price *Turnaround time Order
NM_005755 Homo sapiens Epstein-Barr virus induced 3 (EBI3), mRNA. GenEZ ORF Cloning In-stock $308.00 $259.00 10
XM_006722605 PREDICTED: Homo sapiens Epstein-Barr virus induced 3 (EBI3), transcript variant X1, mRNA. GenEZ ORF Cloning On-demand $449.00 14

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Related Services

Gene Symbol EBI3
Entrez Gene ID 10148
Full Name Epstein-Barr virus induced 3
Synonyms IL-27B, IL27B
General protein information
Preferred Names
interleukin-27 subunit beta
Names
interleukin-27 subunit beta
IL27 subunit
IL35 subunit
cytokine receptor
IL-27 subunit beta
EBV-induced gene 3 protein
Epstein-Barr virus induced gene 3
epstein-Barr virus-induced gene 3 protein
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

19

19p13.3

Summary This gene was identified by its induced expression in B lymphocytes in response Epstein-Barr virus infection. It encodes a secreted glycoprotein belonging to the hematopoietin receptor family, and heterodimerizes with a 28 kDa protein to form interleukin 27 (IL-27). IL-27 regulates T cell and inflammatory responses, in part by activating the Jak/STAT pathway of CD4+ T cells. [provided by RefSeq, Sep 2008].
Disorder

MIM: 605816

mRNA Protein Product Sequence Price Select
NM_005755, 14577916 NP_005746, 14577917 interleukin-27 subunit beta precursor ORF Sequence $159.00
XM_006722605, 578832890 XP_006722668, 578832891 interleukin-27 subunit beta isoform X1 ORF Sequence $300.00
Pathway Interaction Database
il27pathwayIL27-mediated signaling events
Homo sapiens (human)EBI3NP_005746.2
Pan troglodytes (chimpanzee)EBI3XP_001138182.1
Canis lupus familiaris (dog)EBI3XP_542161.3
Bos taurus (cattle)EBI3NP_001093835.1
Mus musculus (house mouse)Ebi3NP_056581.1
Rattus norvegicus (Norway rat)Ebi3NP_001102891.1
Danio rerio (zebrafish)ebi3NP_001106980.1
Xenopus (Silurana) tropicalis (western clawed frog)ebi3XP_002934057.1
Process
IDNameEvidence
GO:0006959humoral immune responseTAS
GO:0019221cytokine-mediated signaling pathwayIEA
GO:0019221cytokine-mediated signaling pathwayIPI
GO:0042088T-helper 1 type immune responseTAS
GO:0045078positive regulation of interferon-gamma biosynthetic processTAS
GO:0046641positive regulation of alpha-beta T cell proliferationTAS
Component
IDNameEvidence
GO:0005615extracellular spaceIEA
GO:0005886plasma membraneTAS
Function
IDNameEvidence
GO:0004896cytokine receptor activityIPI
GO:0005125cytokine activityIEA
GO:0005515protein bindingIPI
GO:0045523interleukin-27 receptor bindingIEA
GeneCards EBI3
UniProt Q14213
Vega OTTHUMG00000181866
MIM 605816
Ensembl ENSG00000105246
HGNC 3129
HPRD 12051

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Interactant

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