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Sequence in raw or FASTA format:

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MAD2L2 MAD2 mitotic arrest deficient-like 2 (yeast) [Homo sapiens (human)]


RefSeq Accession Definition Services Price Order
NM_001127325 Homo sapiens MAD2 mitotic arrest deficient-like 2 (yeast) (MAD2L2), transcript variant 1, mRNA. ORF Sequence $184.44
Peptide Services
Antibody Services
Protein Services
NM_006341 Homo sapiens MAD2 mitotic arrest deficient-like 2 (yeast) (MAD2L2), transcript variant 2, mRNA. ORF Sequence $184.44
Peptide Services
Antibody Services
Protein Services


Gene Symbol MAD2L2
Entrez Gene ID 10459
Full Name MAD2 mitotic arrest deficient-like 2 (yeast)
Synonyms MAD2B, REV7
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

1

1p36

Summary The protein encoded by this gene is a component of the mitotic spindle assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. The encoded protein, which is similar to MAD2L1, is capable of interacting with ADAM9, ADAM15, REV1, and REV3 proteins. [provided by RefSeq, Jul 2008].
Disorder

MIM: 604094

mRNA Protein Product Sequence Price Select
NM_001127325, 187960078 NP_001120797, 187960079 mitotic spindle assembly checkpoint protein MAD2B Full Length $346.84
ORF Sequence $184.44
NM_006341, 187960072 NP_006332, 187960073 mitotic spindle assembly checkpoint protein MAD2B Full Length $337.27
ORF Sequence $184.44
KEGG
hsa05131Shigellosis
hsa05100Bacterial invasion of epithelial cells
hsa04110Cell cycle
hsa04914Progesterone-mediated oocyte maturation
hsa_M00293DNA polymerase zeta complex
hsa04114Oocyte meiosis
WikiPathways
WP179Cell cycle
Reactome
REACT_2174DNA Damage Bypass
REACT_822Translesion synthesis by Pol zeta
REACT_216DNA Repair
REACT_2198Translesion synthesis by DNA polymerases bypassing lesion on DNA template
Homo sapiens (human)MAD2L2NP_006332.3
Pan troglodytes (chimpanzee)MAD2L2XP_001138745.1
Macaca mulatta (Rhesus monkey)MAD2L2XP_001104002.1
Canis lupus familiaris (dog)MAD2L2XP_544568.3
Bos taurus (cattle)MAD2L2NP_001039411.1
Mus musculus (house mouse)Mad2l2NP_082261.2
Gallus gallus (chicken)MAD2L2NP_001020749.1
Danio rerio (zebrafish)si:dkey-23c22.2NP_001017595.1
Danio rerio (zebrafish)LOC557968XP_685100.1
Arabidopsis thaliana (thale cress)REV7NP_564002.1
GeneCards MAD2L2
PDB 4GK5, 4GK0, 3ABD, 3VU7, 3ABE
UniProt Q9UI95
MIM 604094
Ensembl ENSG00000116670
HGNC 6764
HPRD 07246

GeneRIFs: Gene References Into Functions What's a GeneRIF?

General protein information

Preferred Names
mitotic spindle assembly checkpoint protein MAD2B
Names
mitotic spindle assembly checkpoint protein MAD2B
hREV7
REV7 homolog
MAD2-like protein 2
mitotic arrest deficient homolog-like 2
mitotic arrest deficient 2-like protein 2
polymerase (DNA-directed), zeta 2, accessory subunit
MAD2 (mitotic arrest deficient, yeast, homolog)-like 2

Interactant

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