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Sequence in raw or FASTA format:

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IL1RAPL1 interleukin 1 receptor accessory protein-like 1 [Homo sapiens (human)]


Clone ID RefSeq Accession Definition Vector Stock Status *Turnaround time Price Order
OHu19152 NM_014271 Homo sapiens interleukin 1 receptor accessory protein-like 1 (IL1RAPL1), mRNA. pcDNA3.1+-DYK In-stock 5-7 $99.00
OHu19152 XM_005274441 PREDICTED: Homo sapiens interleukin 1 receptor accessory protein-like 1 (IL1RAPL1), transcript variant X1, mRNA. pcDNA3.1+-DYK On-demand 12-14 $279.00
OHu19152C NM_014271 Homo sapiens interleukin 1 receptor accessory protein-like 1 (IL1RAPL1), mRNA. Customized vector In-stock 5-7 $149.00
OHu19152C XM_005274441 PREDICTED: Homo sapiens interleukin 1 receptor accessory protein-like 1 (IL1RAPL1), transcript variant X1, mRNA. Customized vector On-demand 12-14 $329.00

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Gene Symbol IL1RAPL1
Entrez Gene ID 11141
Full Name interleukin 1 receptor accessory protein-like 1
Synonyms IL1R8, IL1RAPL, MRX10, MRX21, MRX34, OPHN4, TIGIRR-2
General protein information
Preferred Names
interleukin-1 receptor accessory protein-like 1
Names
interleukin-1 receptor accessory protein-like 1
IL1RAPL-1
IL-1RAPL-1
IL-1-RAPL-1
oligophrenin-4
interleukin 1 receptor-8
mental retardation, X-linked 10
X-linked interleukin-1 receptor accessory protein-like 1
three immunoglobulin domain-containing IL-1 receptor-related 2
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

X

Xp22.1-p21.3

Summary The protein encoded by this gene is a member of the interleukin 1 receptor family and is similar to the interleukin 1 accessory proteins. It is most closely related to interleukin 1 receptor accessory protein-like 2 (IL1RAPL2). This gene and IL1RAPL2 are located at a region on chromosome X that is associated with X-linked non-syndromic mental retardation. Deletions and mutations in this gene were found in patients with mental retardation. This gene is expressed at a high level in post-natal brain structures involved in the hippocampal memory system, which suggests a specialized role in the physiological processes underlying memory and learning abilities. [provided by RefSeq, Jul 2008].
Disorder

MIM: 300206

Mental retardation, X-linked, 21/34, 300143 (3)

mRNA Protein Product Sequence Price Select
NM_014271, 183396800 NP_055086, 7657232 interleukin-1 receptor accessory protein-like 1 precursor ORF Sequence $490.00
XM_005274441, 530420953 XP_005274498, 530420954 interleukin-1 receptor accessory protein-like 1 isoform X1 ORF Sequence $700.00
Homo sapiens (human)IL1RAPL1NP_055086.1
Pan troglodytes (chimpanzee)IL1RAPL1NP_001009038.1
Macaca mulatta (Rhesus monkey)IL1RAPL1XP_001094959.1
Canis lupus familiaris (dog)IL1RAPL1XP_548919.3
Bos taurus (cattle)IL1RAPL1XP_002700320.2
Mus musculus (house mouse)Il1rapl1NP_001153875.1
Rattus norvegicus (Norway rat)Il1rapl1NP_808796.1
Gallus gallus (chicken)IL1RAPL1XP_425563.3
Danio rerio (zebrafish)il1rapl1bNP_001136054.1
Xenopus (Silurana) tropicalis (western clawed frog)il1rapl1XP_002933660.1
Process
IDNameEvidence
GO:0007157heterophilic cell-cell adhesionISS
GO:0007165signal transductionIEA
GO:0010975regulation of neuron projection developmentISS
GO:0030182neuron differentiationISS
GO:0045920negative regulation of exocytosisIDA
GO:0050775positive regulation of dendrite morphogenesisISS
GO:0070588calcium ion transmembrane transportISS
GO:0097105presynaptic membrane assemblyISS
Component
IDNameEvidence
GO:0005737cytoplasmIEA
GO:0005886plasma membraneIDA
GO:0009986cell surfaceISS
GO:0016021integral component of membraneIEA
GO:0030424axonIEA
GO:0030425dendriteISS
GO:0045211postsynaptic membraneNAS
Function
IDNameEvidence
GO:0005102receptor bindingISS
GO:0005245voltage-gated calcium channel activityISS
GO:0005515protein bindingIPI
GO:0019966interleukin-1 bindingIDA
GeneCards IL1RAPL1
UniProt Q9NZN1, X5DNQ7
MIM 300206
HGNC 5996
HPRD 02193

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Interactant

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