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Sequence in raw or FASTA format:

Database:

Blast Method:

 
 


Apc adenomatosis polyposis coli [Mus musculus (house mouse)]


Clone ID RefSeq Accession Definition Vector Stock Status *Turnaround time Price Order
OMu22391 NM_007462 Mus musculus adenomatosis polyposis coli (Apc), mRNA. pcDNA3.1+-DYK On-demand 40 $4749.00
OMu54317 XM_006525529 PREDICTED: Mus musculus adenomatosis polyposis coli (Apc), transcript variant X1, mRNA. pcDNA3.1+-DYK On-demand TBD TBD
OMu54318 XM_006525530 PREDICTED: Mus musculus adenomatosis polyposis coli (Apc), transcript variant X2, mRNA. pcDNA3.1+-DYK On-demand 40 $4749.00
OMu54318 XM_006525531 PREDICTED: Mus musculus adenomatosis polyposis coli (Apc), transcript variant X3, mRNA. pcDNA3.1+-DYK On-demand 40 $4749.00
OMu54319 XM_006525532 PREDICTED: Mus musculus adenomatosis polyposis coli (Apc), transcript variant X4, mRNA. pcDNA3.1+-DYK On-demand TBD TBD
OMu54320 XM_006525533 PREDICTED: Mus musculus adenomatosis polyposis coli (Apc), transcript variant X5, mRNA. pcDNA3.1+-DYK On-demand 40 $4749.00
OMu54321 XM_006525534 PREDICTED: Mus musculus adenomatosis polyposis coli (Apc), transcript variant X6, mRNA. pcDNA3.1+-DYK On-demand TBD TBD
OMu54322 XM_006525535 PREDICTED: Mus musculus adenomatosis polyposis coli (Apc), transcript variant X7, mRNA. pcDNA3.1+-DYK On-demand 40 $4749.00
OMu54322 XM_006525536 PREDICTED: Mus musculus adenomatosis polyposis coli (Apc), transcript variant X8, mRNA. pcDNA3.1+-DYK On-demand 40 $4749.00
OMu54322 XM_006525537 PREDICTED: Mus musculus adenomatosis polyposis coli (Apc), transcript variant X9, mRNA. pcDNA3.1+-DYK On-demand 40 $4749.00
OMu54323 XM_006525538 PREDICTED: Mus musculus adenomatosis polyposis coli (Apc), transcript variant X10, mRNA. pcDNA3.1+-DYK On-demand TBD TBD
OMu54324 XM_006525539 PREDICTED: Mus musculus adenomatosis polyposis coli (Apc), transcript variant X11, mRNA. pcDNA3.1+-DYK On-demand 40 $4749.00
OMu22391C NM_007462 Mus musculus adenomatosis polyposis coli (Apc), mRNA. Customized vector On-demand 40 $4749.00
OMu54317C XM_006525529 PREDICTED: Mus musculus adenomatosis polyposis coli (Apc), transcript variant X1, mRNA. Customized vector On-demand TBD TBD
OMu54318C XM_006525530 PREDICTED: Mus musculus adenomatosis polyposis coli (Apc), transcript variant X2, mRNA. Customized vector On-demand 40 $4749.00
OMu54318C XM_006525531 PREDICTED: Mus musculus adenomatosis polyposis coli (Apc), transcript variant X3, mRNA. Customized vector On-demand 40 $4749.00
OMu54319C XM_006525532 PREDICTED: Mus musculus adenomatosis polyposis coli (Apc), transcript variant X4, mRNA. Customized vector On-demand TBD TBD
OMu54320C XM_006525533 PREDICTED: Mus musculus adenomatosis polyposis coli (Apc), transcript variant X5, mRNA. Customized vector On-demand 40 $4749.00
OMu54321C XM_006525534 PREDICTED: Mus musculus adenomatosis polyposis coli (Apc), transcript variant X6, mRNA. Customized vector On-demand TBD TBD
OMu54322C XM_006525535 PREDICTED: Mus musculus adenomatosis polyposis coli (Apc), transcript variant X7, mRNA. Customized vector On-demand 40 $4749.00
OMu54322C XM_006525536 PREDICTED: Mus musculus adenomatosis polyposis coli (Apc), transcript variant X8, mRNA. Customized vector On-demand 40 $4749.00
OMu54322C XM_006525537 PREDICTED: Mus musculus adenomatosis polyposis coli (Apc), transcript variant X9, mRNA. Customized vector On-demand 40 $4749.00
OMu54323C XM_006525538 PREDICTED: Mus musculus adenomatosis polyposis coli (Apc), transcript variant X10, mRNA. Customized vector On-demand TBD TBD
OMu54324C XM_006525539 PREDICTED: Mus musculus adenomatosis polyposis coli (Apc), transcript variant X11, mRNA. Customized vector On-demand 40 $4749.00

*Business Day

Related Services

Gene Symbol Apc
Entrez Gene ID 11789
Full Name adenomatosis polyposis coli
Synonyms AI047805, AU020952, AW124434, CC1, Min, mAPC
General protein information
Preferred Names
adenomatous polyposis coli protein
Names
adenomatous polyposis coli protein
multiple intestinal neoplasia
Gene Type protein-coding
Organism Mus musculus (house mouse)
Genome

18

18 B1|18 18.53 cM

Summary
Disorder

MIM:

mRNA Protein Product Sequence Price Select
NM_007462, 158966685 NP_031488, 110225370 adenomatous polyposis coli protein ORF Sequence $4500.00
XM_006525529, 569003028 XP_006525592, 569003029 adenomatous polyposis coli protein isoform X1 ORF Sequence $4500.00
XM_006525530, 569003030 XP_006525593, 569003031 adenomatous polyposis coli protein isoform X2 ORF Sequence $4500.00
XM_006525531, 569003032 XP_006525594, 569003033 adenomatous polyposis coli protein isoform X3 ORF Sequence $4500.00
XM_006525532, 569003034 XP_006525595, 569003035 adenomatous polyposis coli protein isoform X4 ORF Sequence $4500.00
XM_006525533, 569003036 XP_006525596, 569003037 adenomatous polyposis coli protein isoform X5 ORF Sequence $4500.00
XM_006525534, 569003038 XP_006525597, 569003039 adenomatous polyposis coli protein isoform X6 ORF Sequence $4500.00
XM_006525535, 569003040 XP_006525598, 569003041 adenomatous polyposis coli protein isoform X7 ORF Sequence $4500.00
XM_006525536, 569003042 XP_006525599, 569003043 adenomatous polyposis coli protein isoform X8 ORF Sequence $4500.00
XM_006525537, 569003044 XP_006525600, 569003045 adenomatous polyposis coli protein isoform X9 ORF Sequence $4500.00
XM_006525538, 569003046 XP_006525601, 569003047 adenomatous polyposis coli protein isoform X10 ORF Sequence $4500.00
XM_006525539, 569003048 XP_006525602, 569003049 adenomatous polyposis coli protein isoform X11 ORF Sequence $4500.00
KEGG
mmu04310Wnt signaling pathway
mmu04810Regulation of actin cytoskeleton
mmu05213Endometrial cancer
mmu05200Pathways in cancer
mmu05210Colorectal cancer
mmu05217Basal cell carcinoma
mmu05166HTLV-I infection
mmu04390Hippo signaling pathway
mmu05206MicroRNAs in cancer
WikiPathways
WP1763PluriNetWork
WP403Wnt Signaling Pathway
WP339ESC Pluripotency Pathways
WP539Wnt Signaling Pathway NetPath
WP523Regulation of Actin Cytoskeleton
WP475Irinotecan Pathway
WP723Wnt Signaling Pathway and Pluripotency
WP2309XPodNet - protein-protein interactions in the podocyte expanded by STRING
Reactome
5605983deactivation of the beta-catenin transactivating complex
5605352Degradation of beta-catenin by the destruction complex
5605190Signaling by Wnt
5604774Signal Transduction
5605353Beta-catenin phosphorylation cascade
5604708Apoptosis
5605399disassembly of the destruction complex and recruitment of AXIN to the membrane
5605398TCF dependent signaling in response to WNT
5605395Apoptotic execution phase
5605394Apoptotic cleavage of cellular proteins
Homo sapiens (human)APCNP_001120982.1
Pan troglodytes (chimpanzee)APCXP_001143965.1
Canis lupus familiaris (dog)APCXP_005618091.1
Bos taurus (cattle)APCNP_001069454.2
Mus musculus (house mouse)ApcNP_031488.2
Rattus norvegicus (Norway rat)ApcNP_036631.1
Gallus gallus (chicken)APCXP_004949340.1
Danio rerio (zebrafish)apcNP_001137312.1
Xenopus (Silurana) tropicalis (western clawed frog)apcXP_004910521.1
Process
IDNameEvidence
GO:0000281mitotic cytokinesisIMP
GO:0000281mitotic cytokinesisISO
GO:0001822kidney developmentIMP
GO:0001942hair follicle developmentIMP
GO:0006461protein complex assemblyISO
GO:0006974cellular response to DNA damage stimulusISO
GO:0007026negative regulation of microtubule depolymerizationIMP
GO:0007026negative regulation of microtubule depolymerizationISO
GO:0007050cell cycle arrestISO
GO:0007091metaphase/anaphase transition of mitotic cell cycleIGI
GO:0007091metaphase/anaphase transition of mitotic cell cycleIMP
GO:0007094mitotic spindle assembly checkpointISO
GO:0007163establishment or maintenance of cell polarityISO
GO:0007389pattern specification processIMP
GO:0007409axonogenesisIGI
GO:0007409axonogenesisIMP
GO:0008285negative regulation of cell proliferationIGI
GO:0008285negative regulation of cell proliferationIMP
GO:0008285negative regulation of cell proliferationISO
GO:0009798axis specificationIMP
GO:0009952anterior/posterior pattern specificationIMP
GO:0009953dorsal/ventral pattern formationIMP
GO:0009954proximal/distal pattern formationIMP
GO:0016055Wnt signaling pathwayIDA
GO:0016055Wnt signaling pathwayIMP
GO:0016477cell migrationIMP
GO:0016477cell migrationISO
GO:0019827stem cell maintenanceIMP
GO:0030178negative regulation of Wnt signaling pathwayIGI
GO:0030178negative regulation of Wnt signaling pathwayIMP
GO:0030334regulation of cell migrationIGI
GO:0030334regulation of cell migrationIMP
GO:0030335positive regulation of cell migrationIMP
GO:0030335positive regulation of cell migrationISO
GO:0030856regulation of epithelial cell differentiationIMP
GO:0030858positive regulation of epithelial cell differentiationIGI
GO:0031116positive regulation of microtubule polymerizationIMP
GO:0031122cytoplasmic microtubule organizationIGI
GO:0031175neuron projection developmentISO
GO:0031274positive regulation of pseudopodium assemblyISO
GO:0032886regulation of microtubule-based processISO
GO:0033077T cell differentiation in thymusIMP
GO:0035019somatic stem cell maintenanceIGI
GO:0035019somatic stem cell maintenanceIMP
GO:0042483negative regulation of odontogenesisIMP
GO:0043065positive regulation of apoptotic processIMP
GO:0043065positive regulation of apoptotic processISO
GO:0043066negative regulation of apoptotic processIMP
GO:0043409negative regulation of MAPK cascadeIGI
GO:0043409negative regulation of MAPK cascadeIMP
GO:0043588skin developmentIMP
GO:0044336canonical Wnt signaling pathway involved in negative regulation of apoptotic processIGI
GO:0044337canonical Wnt signaling pathway involved in positive regulation of apoptotic processIGI
GO:0045595regulation of cell differentiationIGI
GO:0045597positive regulation of cell differentiationIMP
GO:0045667regulation of osteoblast differentiationIMP
GO:0045670regulation of osteoclast differentiationIMP
GO:0045732positive regulation of protein catabolic processIMP
GO:0045732positive regulation of protein catabolic processISO
GO:0045736negative regulation of cyclin-dependent protein serine/threonine kinase activityISO
GO:0045785positive regulation of cell adhesionIMP
GO:0046716muscle cell cellular homeostasisIGI
GO:0048538thymus developmentIMP
GO:0050680negative regulation of epithelial cell proliferationIGI
GO:0050680negative regulation of epithelial cell proliferationIMP
GO:0051171regulation of nitrogen compound metabolic processIMP
GO:0051276chromosome organizationIGI
GO:0051276chromosome organizationIMP
GO:0051726regulation of cell cycleIMP
GO:0051781positive regulation of cell divisionIMP
GO:0051988regulation of attachment of spindle microtubules to kinetochoreIMP
GO:0051988regulation of attachment of spindle microtubules to kinetochoreISO
GO:0060041retina development in camera-type eyeIMP
GO:0060070canonical Wnt signaling pathwayIMP
GO:0060770negative regulation of epithelial cell proliferation involved in prostate gland developmentIMP
GO:0090090negative regulation of canonical Wnt signaling pathwayIMP
GO:0090090negative regulation of canonical Wnt signaling pathwayISO
GO:2000211regulation of glutamate metabolic processISO
Component
IDNameEvidence
GO:0000776kinetochoreISO
GO:0005634nucleusIDA
GO:0005634nucleusISO
GO:0005737cytoplasmIDA
GO:0005737cytoplasmISO
GO:0005813centrosomeISO
GO:0005856cytoskeletonIEA
GO:0005874microtubuleISO
GO:0005881cytoplasmic microtubuleIDA
GO:0005886plasma membraneISO
GO:0005886plasma membraneISO
GO:0005913cell-cell adherens junctionISO
GO:0005923tight junctionISO
GO:0005938cell cortexISO
GO:0016020membraneIEA
GO:0016328lateral plasma membraneISO
GO:0030027lamellipodiumISO
GO:0030054cell junctionIEA
GO:0030424axonIDA
GO:0030425dendriteISO
GO:0030426growth coneIDA
GO:0030426growth coneISO
GO:0030877beta-catenin destruction complexISO
GO:0031253cell projection membraneIDA
GO:0031965nuclear membraneISO
GO:0032587ruffle membraneISO
GO:0034750Scrib-APC-beta-catenin complexIDA
GO:0035371microtubule plus-endIDA
GO:0042995cell projectionIDA
GO:0043005neuron projectionISO
GO:0043025neuronal cell bodyISO
GO:0043234protein complexISO
GO:0044295axonal growth coneIDA
GO:0044295axonal growth coneISO
GO:0044306neuron projection terminusISO
GO:0045202synapseISO
GO:0070852cell body fiberISO
Function
IDNameEvidence
GO:0002020protease bindingIPI
GO:0005515protein bindingIPI
GO:0008013beta-catenin bindingIDA
GO:0008013beta-catenin bindingIPI
GO:0008013beta-catenin bindingISO
GO:0008017microtubule bindingISO
GO:0019887protein kinase regulator activityISO
GO:0019901protein kinase bindingISO
GO:0032403protein complex bindingISO
GO:0045295gamma-catenin bindingISO
GO:0051010microtubule plus-end bindingIDA
GO:0051010microtubule plus-end bindingISO
GeneCards Apc
UniProt B2RUG9, Q8BNP7
MGI 88039
Ensembl ENSMUSG00000005871

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Interactant

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