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Sequence in raw or FASTA format:

Database:

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Btk Bruton agammaglobulinemia tyrosine kinase [Mus musculus (house mouse)]


Clone ID RefSeq Accession Definition Vector Stock Status *Turnaround time Price Order
OMu18686 NM_013482 Mus musculus Bruton agammaglobulinemia tyrosine kinase (Btk), mRNA. pcDNA3.1+-DYK On-demand 7-9 $219.00
OMu18686 XM_006528483 PREDICTED: Mus musculus Bruton agammaglobulinemia tyrosine kinase (Btk), transcript variant X1, mRNA. pcDNA3.1+-DYK On-demand 7-9 $219.00
OMu18686 XM_006528484 PREDICTED: Mus musculus Bruton agammaglobulinemia tyrosine kinase (Btk), transcript variant X2, mRNA. pcDNA3.1+-DYK On-demand 7-9 $219.00
OMu18686 XM_006528485 PREDICTED: Mus musculus Bruton agammaglobulinemia tyrosine kinase (Btk), transcript variant X3, mRNA. pcDNA3.1+-DYK On-demand 7-9 $219.00
OMu18686C NM_013482 Mus musculus Bruton agammaglobulinemia tyrosine kinase (Btk), mRNA. Customized vector On-demand 7-9 $269.00
OMu18686C XM_006528483 PREDICTED: Mus musculus Bruton agammaglobulinemia tyrosine kinase (Btk), transcript variant X1, mRNA. Customized vector On-demand 7-9 $269.00
OMu18686C XM_006528484 PREDICTED: Mus musculus Bruton agammaglobulinemia tyrosine kinase (Btk), transcript variant X2, mRNA. Customized vector On-demand 7-9 $269.00
OMu18686C XM_006528485 PREDICTED: Mus musculus Bruton agammaglobulinemia tyrosine kinase (Btk), transcript variant X3, mRNA. Customized vector On-demand 7-9 $269.00

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Gene Symbol Btk
Entrez Gene ID 12229
Full Name Bruton agammaglobulinemia tyrosine kinase
Synonyms AI528679, xid
General protein information
Preferred Names
tyrosine-protein kinase BTK
Names
tyrosine-protein kinase BTK
ATK
BPK
kinase EMB
bruton tyrosine kinase
B-cell progenitor kinase
Bruton's tyrosine kinase
X-linked immune deficiency
agammaglobulinemia tyrosine kinase
agammaglobulinaemia tyrosine kinase
Tyrosine-protein kinase BTK (Brutons tyrosine kinase) (Agammaglobulinaemia tyrosine kinase) (ATK) (B cell progenitor kinase) (BPK) (Kinase EMB)
NP_038510.2
Gene Type protein-coding
Organism Mus musculus (house mouse)
Genome

X

X E3|X 56.18 cM

Summary
Disorder

MIM:

mRNA Protein Product Sequence Price Select
NM_013482, 161016838 NP_038510, 161016839 tyrosine-protein kinase BTK ORF Sequence $700.00
XM_006528483, 569011231 XP_006528546, 569011232 tyrosine-protein kinase BTK isoform X1 ORF Sequence $700.00
XM_006528484, 569011233 XP_006528547, 569011234 tyrosine-protein kinase BTK isoform X2 ORF Sequence $700.00
XM_006528485, 569011235 XP_006528548, 569011236 tyrosine-protein kinase BTK isoform X3 ORF Sequence $700.00
KEGG
mmu04664Fc epsilon RI signaling pathway
mmu04662B cell receptor signaling pathway
mmu05340Primary immunodeficiency
mmu04380Osteoclast differentiation
mmu04064NF-kappa B signaling pathway
mmu04611Platelet activation
WikiPathways
WP151IL-5 Signaling Pathway
WP387IL-6 signaling Pathway
WP274B Cell Receptor Signaling Pathway
WP407Kit Receptor Signaling Pathway
Reactome
5604809FCERI mediated Ca+2 mobilization
5604802Innate Immune System
5604807Signaling by the B Cell Receptor (BCR)
5604806Antigen activates B Cell Receptor (BCR) leading to generation of second messengers
5604803Immune System
5604808Adaptive Immune System
5604801DAP12 interactions
5604800DAP12 signaling
5604810Fc epsilon receptor (FCERI) signaling
Homo sapiens (human)BTKNP_001274273.1
Pan troglodytes (chimpanzee)BTKXP_001139132.2
Macaca mulatta (Rhesus monkey)BTKXP_002806376.1
Canis lupus familiaris (dog)BTKXP_549139.2
Bos taurus (cattle)BTKNP_001029761.1
Mus musculus (house mouse)BtkNP_038510.2
Rattus norvegicus (Norway rat)BtkNP_001007799.1
Gallus gallus (chicken)BTKNP_989564.2
Danio rerio (zebrafish)btkXP_697087.4
Xenopus (Silurana) tropicalis (western clawed frog)btkNP_001123732.1
Process
IDNameEvidence
GO:0002376immune system processIEA
GO:0002553histamine secretion by mast cellISO
GO:0006351transcription, DNA-templatedIEA
GO:0006355regulation of transcription, DNA-templatedIEA
GO:0006468protein phosphorylationIDA
GO:0006915apoptotic processIEA
GO:0007249I-kappaB kinase/NF-kappaB signalingIMP
GO:0010033response to organic substanceISO
GO:0016310phosphorylationIEA
GO:0018108peptidyl-tyrosine phosphorylationIDA
GO:0018108peptidyl-tyrosine phosphorylationISO
GO:0034614cellular response to reactive oxygen speciesISO
GO:0035556intracellular signal transductionIEA
GO:0045087innate immune responseIEA
GO:0046777protein autophosphorylationISO
GO:0048469cell maturationIMP
GO:0071226cellular response to molecule of fungal originISO
Component
IDNameEvidence
GO:0005622intracellularIMP
GO:0005634nucleusIDA
GO:0005737cytoplasmIDA
GO:0005829cytosolISO
GO:0005886plasma membraneISO
GO:0016020membraneIEA
GO:0031410cytoplasmic vesicleIDA
GO:0042629mast cell granuleISO
GO:0043231intracellular membrane-bounded organelleISO
GO:0045121membrane raftISO
GO:0048471perinuclear region of cytoplasmISO
Function
IDNameEvidence
GO:0000166nucleotide bindingIEA
GO:0004672protein kinase activityIEA
GO:0004713protein tyrosine kinase activityIDA
GO:0004713protein tyrosine kinase activityISO
GO:0004715non-membrane spanning protein tyrosine kinase activityIEA
GO:0005515protein bindingIPI
GO:0005524ATP bindingIEA
GO:0005547phosphatidylinositol-3,4,5-trisphosphate bindingISO
GO:0008289lipid bindingIEA
GO:0016301kinase activityIEA
GO:0016740transferase activityIEA
GO:0016772transferase activity, transferring phosphorus-containing groupsIEA
GO:0042802identical protein bindingISO
GO:0046872metal ion bindingIEA
GeneCards Btk
UniProt P35991
MGI 88216
Vega OTTMUSG00000019307
Ensembl ENSMUSG00000031264

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Interactant

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