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Sequence in raw or FASTA format:

Database:

Blast Method:

 
 


Cd3e CD3 antigen, epsilon polypeptide [Mus musculus (house mouse)]


Clone ID RefSeq Accession Definition Vector Stock Status *Turnaround time Price Order
OMu20096 NM_007648 Mus musculus CD3 antigen, epsilon polypeptide (Cd3e), mRNA. pcDNA3.1+-DYK On-demand 7-9 $159.00
OMu20096 XM_006509966 PREDICTED: Mus musculus CD3 antigen, epsilon polypeptide (Cd3e), transcript variant X1, mRNA. pcDNA3.1+-DYK On-demand 7-9 $159.00
OMu20096C NM_007648 Mus musculus CD3 antigen, epsilon polypeptide (Cd3e), mRNA. Customized vector On-demand 7-9 $209.00
OMu20096C XM_006509966 PREDICTED: Mus musculus CD3 antigen, epsilon polypeptide (Cd3e), transcript variant X1, mRNA. Customized vector On-demand 7-9 $209.00

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Gene Symbol Cd3e
Entrez Gene ID 12501
Full Name CD3 antigen, epsilon polypeptide
Synonyms AI504783, CD3, CD3epsilon, T3e
General protein information
Preferred Names
T-cell surface glycoprotein CD3 epsilon chain
Names
T-cell surface glycoprotein CD3 epsilon chain
T-cell surface antigen T3/Leu-4 epsilon chain
Gene Type protein-coding
Organism Mus musculus (house mouse)
Genome

9

9 A5.2|9 24.84 cM

Summary
Disorder

MIM:

mRNA Protein Product Sequence Price Select
NM_007648, 158508719 NP_031674, 6680886 T-cell surface glycoprotein CD3 epsilon chain precursor ORF Sequence $250.00
XM_006509966, 568958758 XP_006510029, 568958759 T-cell surface glycoprotein CD3 epsilon chain isoform X1 ORF Sequence $250.00
KEGG
mmu04640Hematopoietic cell lineage
mmu04660T cell receptor signaling pathway
mmu05340Primary immunodeficiency
mmu05142Chagas disease (American trypanosomiasis)
mmu05166HTLV-I infection
mmu05162Measles
WikiPathways
WP480T Cell Receptor Signaling Pathway
WP2309XPodNet - protein-protein interactions in the podocyte expanded by STRING
Reactome
5605408Translocation of ZAP-70 to Immunological synapse
5605409Generation of second messenger molecules
5605546PD-1 signaling
5605383Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
5604803Immune System
5604808Adaptive Immune System
5605366Costimulation by the CD28 family
5605407Phosphorylation of CD3 and TCR zeta chains
5605405Downstream TCR signaling
5605406TCR signaling
Homo sapiens (human)CD3ENP_000724.1
Pan troglodytes (chimpanzee)CD3EXP_001160742.1
Macaca mulatta (Rhesus monkey)CD3EXP_001097204.1
Canis lupus familiaris (dog)CD3ENP_001003379.1
Bos taurus (cattle)CD3ENP_776436.1
Mus musculus (house mouse)Cd3eNP_031674.1
Rattus norvegicus (Norway rat)Cd3eNP_001101610.1
Gallus gallus (chicken)CD3ENP_996787.1
Xenopus (Silurana) tropicalis (western clawed frog)cd3eXP_002932946.1
Process
IDNameEvidence
GO:0002669positive regulation of T cell anergyIDA
GO:0007166cell surface receptor signaling pathwayIDA
GO:0007584response to nutrientISO
GO:0031295T cell costimulationIGI
GO:0032729positive regulation of interferon-gamma productionIDA
GO:0032753positive regulation of interleukin-4 productionIDA
GO:0042102positive regulation of T cell proliferationIDA
GO:0042102positive regulation of T cell proliferationISO
GO:0045060negative thymic T cell selectionIDA
GO:0045086positive regulation of interleukin-2 biosynthetic processIDA
GO:0045879negative regulation of smoothened signaling pathwayIDA
GO:0046641positive regulation of alpha-beta T cell proliferationIDA
GO:0046649lymphocyte activationIMP
GO:0050731positive regulation of peptidyl-tyrosine phosphorylationIDA
GO:0050850positive regulation of calcium-mediated signalingIDA
GO:0050852T cell receptor signaling pathwayIDA
GO:0050870positive regulation of T cell activationIDA
GO:0097190apoptotic signaling pathwayIDA
Component
IDNameEvidence
GO:0001772immunological synapseIDA
GO:0005886plasma membraneISO
GO:0005911cell-cell junctionIDA
GO:0009897external side of plasma membraneIDA
GO:0009897external side of plasma membraneISO
GO:0016020membraneIEA
GO:0016021integral component of membraneIEA
GO:0042101T cell receptor complexISO
GO:0042105alpha-beta T cell receptor complexIDA
Function
IDNameEvidence
GO:0004871signal transducer activityIDA
GO:0004888transmembrane signaling receptor activityIEA
GO:0005515protein bindingIPI
GO:0017124SH3 domain bindingISO
GO:0046982protein heterodimerization activityISO
GeneCards Cd3e
PDB 3R08, 2K4F, 1XMW, 1JBJ
UniProt P22646, A6H6M1
MGI 88332
Vega OTTMUSG00000016712
Ensembl ENSMUSG00000032093

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Interactant

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