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ADH1C alcohol dehydrogenase 1C (class I), gamma polypeptide [Homo sapiens (human)]


Clone ID RefSeq Accession Definition Vector Stock Status *Turnaround time Price Order
OHu27894 NM_000669 Homo sapiens alcohol dehydrogenase 1C (class I), gamma polypeptide (ADH1C), mRNA. pcDNA3.1+-DYK In-stock 5-7 $99.00
OHu27894C NM_000669 Homo sapiens alcohol dehydrogenase 1C (class I), gamma polypeptide (ADH1C), mRNA. Customized vector In-stock 5-7 $149.00

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Gene Symbol ADH1C
Entrez Gene ID 126
Full Name alcohol dehydrogenase 1C (class I), gamma polypeptide
Synonyms ADH3
General protein information
Preferred Names
alcohol dehydrogenase 1C
Names
alcohol dehydrogenase 1C
ADH, gamma subunit
aldehyde reductase
alcohol dehydrogenase subunit gamma
alcohol dehydrogenase 3 (class I), gamma polypeptide
NP_000660.1
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

4

4q23

Summary This gene encodes class I alcohol dehydrogenase, gamma subunit, which is a member of the alcohol dehydrogenase family. Members of this enzyme family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. Class I alcohol dehydrogenase, consisting of several homo- and heterodimers of alpha, beta, and gamma subunits, exhibits high activity for ethanol oxidation and plays a major role in ethanol catabolism. Three genes encoding alpha, beta and gamma subunits are tandemly organized in a genomic segment as a gene cluster. [provided by RefSeq, Jul 2008].
Disorder

MIM: 103730

{Alcohol dependence, protection against}, 103780 (3); {Parkinson

mRNA Protein Product Sequence Price Select
NM_000669, 589269186 NP_000660, 4501933 alcohol dehydrogenase 1C ORF Sequence $269.00
KEGG
hsa00010Glycolysis / Gluconeogenesis
hsa00350Tyrosine metabolism
hsa00980Metabolism of xenobiotics by cytochrome P450
hsa00071Fatty acid degradation
hsa00830Retinol metabolism
hsa00982Drug metabolism - cytochrome P450
hsa05204Chemical carcinogenesis
WikiPathways
WP206Fatty Acid Omega Oxidation
Reactome
REACT_13433Biological oxidations
REACT_34Ethanol oxidation
REACT_13705Phase 1 - Functionalization of compounds
REACT_111217Metabolism
Homo sapiens (human)ADH1CNP_000660.1
Pan troglodytes (chimpanzee)ADH1CXP_001167004.2
Macaca mulatta (Rhesus monkey)ADH1CXP_001099784.1
Canis lupus familiaris (dog)LOC100856533XP_003640155.1
Bos taurus (cattle)ADH1CNP_001193316.1
Mus musculus (house mouse)Adh1NP_031435.1
Rattus norvegicus (Norway rat)Adh1NP_062159.3
Gallus gallus (chicken)ADH1CXP_001234263.3
Xenopus (Silurana) tropicalis (western clawed frog)adh1cNP_001025581.1
Xenopus (Silurana) tropicalis (western clawed frog)LOC100487608XP_002934814.1
Process
IDNameEvidence
GO:0006069ethanol oxidationIDA
GO:0006069ethanol oxidationTAS
GO:0006805xenobiotic metabolic processTAS
GO:0044281small molecule metabolic processTAS
Component
IDNameEvidence
GO:0005829cytosolTAS
Function
IDNameEvidence
GO:0004022alcohol dehydrogenase (NAD) activityIDA
GO:0008270zinc ion bindingIEA
GeneCards ADH1C
PDB 1DDA, 1HT0, 1U3W
UniProt P00326
Vega OTTHUMG00000161422
MIM 103730
Ensembl ENSG00000248144
HGNC 251
HPRD 00066

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Interactant

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