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ADH1C alcohol dehydrogenase 1C (class I), gamma polypeptide [Homo sapiens (human)]


RefSeq Accession Definition Service Stock Status Price *Turnaround time Order
NM_000669 Homo sapiens alcohol dehydrogenase 1C (class I), gamma polypeptide (ADH1C), mRNA. GenEZ ORF Cloning In-stock $418.00 $369.00 10

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Related Services

Gene Symbol ADH1C
Entrez Gene ID 126
Full Name alcohol dehydrogenase 1C (class I), gamma polypeptide
Synonyms ADH3
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

4

4q23

Summary This gene encodes class I alcohol dehydrogenase, gamma subunit, which is a member of the alcohol dehydrogenase family. Members of this enzyme family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. Class I alcohol dehydrogenase, consisting of several homo- and heterodimers of alpha, beta, and gamma subunits, exhibits high activity for ethanol oxidation and plays a major role in ethanol catabolism. Three genes encoding alpha, beta and gamma subunits are tandemly organized in a genomic segment as a gene cluster. [provided by RefSeq, Jul 2008].
Disorder

MIM: 103730

{Alcohol dependence, protection against}, 103780 (3); {Parkinson

mRNA Protein Product Sequence Price Select
NM_000669, 71565150 NP_000660, 4501933 alcohol dehydrogenase 1C ORF Sequence $269.00
KEGG
hsa00982Drug metabolism - cytochrome P450
hsa05204Chemical carcinogenesis
hsa00350Tyrosine metabolism
hsa00980Metabolism of xenobiotics by cytochrome P450
hsa00830Retinol metabolism
hsa00010Glycolysis / Gluconeogenesis
hsa00071Fatty acid metabolism
WikiPathways
WP206Fatty Acid Omega Oxidation
Reactome
REACT_13433Biological oxidations
REACT_111217Metabolism
REACT_13705Phase 1 - Functionalization of compounds
REACT_34Ethanol oxidation
Homo sapiens (human)ADH1CNP_000660.1
Pan troglodytes (chimpanzee)ADH1CXP_001167004.2
Macaca mulatta (Rhesus monkey)ADH1CXP_001099784.1
Canis lupus familiaris (dog)LOC100856533XP_003640155.1
Bos taurus (cattle)ADH1CNP_001193316.1
Mus musculus (house mouse)Adh1NP_031435.1
Rattus norvegicus (Norway rat)Adh1cNP_062159.3
Gallus gallus (chicken)ADH1CXP_001234263.2
GeneCards ADH1C
PDB 1DDA, 1HT0, 1U3W
UniProt P00326
MIM 103730
Ensembl ENSG00000248144
HGNC 251
HPRD 00066

GeneRIFs: Gene References Into Functions What's a GeneRIF?

General protein information

Preferred Names
alcohol dehydrogenase 1C
Names
alcohol dehydrogenase 1C
ADH, gamma subunit
aldehyde reductase
alcohol dehydrogenase subunit gamma
alcohol dehydrogenase 3 (class I), gamma polypeptide
NP_000660.1

Interactant



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