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CYP4F22 cytochrome P450, family 4, subfamily F, polypeptide 22 [Homo sapiens (human)]


Clone ID RefSeq Accession Definition Vector Stock Status *Turnaround time Price Order
OHu18711 NM_173483 Homo sapiens cytochrome P450, family 4, subfamily F, polypeptide 22 (CYP4F22), mRNA. pcDNA3.1+-DYK In-stock 5-7 $99.00
OHu18711C NM_173483 Homo sapiens cytochrome P450, family 4, subfamily F, polypeptide 22 (CYP4F22), mRNA. Customized vector In-stock 5-7 $149.00

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Gene Symbol CYP4F22
Entrez Gene ID 126410
Full Name cytochrome P450, family 4, subfamily F, polypeptide 22
Synonyms ARCI5, INLNE, LI3
General protein information
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

19

19p13.12

Summary This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This gene is part of a cluster of cytochrome P450 genes on chromosome 19 and encodes an enzyme thought to play a role in the 12(R)-lipoxygenase pathway. Mutations in this gene are the cause of ichthyosis lamellar type 3. [provided by RefSeq, Jul 2008].
Disorder

MIM: 611495

Ichthyosis, lamellar, 3, 604777 (3)

mRNA Protein Product Sequence Price Select
NM_173483, 158138529 NP_775754, 158138530 cytochrome P450 4F22 ORF Sequence $360.00
WikiPathways
WP43cytochrome P450
WP702metapathway biotransformation
Reactome
REACT_13433Biological oxidations
REACT_13705Phase 1 - Functionalization of compounds
REACT_13814Fatty acids
REACT_13645Eicosanoids
REACT_13425Miscellaneous substrates
REACT_13567Cytochrome P450 - arranged by substrate type
REACT_22258Metabolism of lipids and lipoproteins
REACT_111217Metabolism
REACT_147851Arachidonic acid metabolism
REACT_150420Synthesis of Leukotrienes (LT) and Eoxins (EX)
Homo sapiens (human)CYP4F22NP_775754.2
Pan troglodytes (chimpanzee)LOC455798XP_512456.2
Macaca mulatta (Rhesus monkey)CYP4F22XP_001111971.1
Canis lupus familiaris (dog)CYP4F22XP_541984.2
Bos taurus (cattle)LOC100301224XP_005208627.1
Mus musculus (house mouse)Cyp4f39NP_796281.1
Rattus norvegicus (Norway rat)Cyp4f39XP_006241154.1
Arabidopsis thaliana (thale cress)CYP735A2NP_176882.1
Arabidopsis thaliana (thale cress)CYP735A1NP_198661.1
Xenopus (Silurana) tropicalis (western clawed frog)cyp4f22NP_001015810.1
Xenopus (Silurana) tropicalis (western clawed frog)LOC548774NP_001016020.1
Process
IDNameEvidence
GO:0055114oxidation-reduction processIEA
Component
IDNameEvidence
GO:0005789endoplasmic reticulum membraneIEA
Function
IDNameEvidence
GO:0004497monooxygenase activityIEA
GO:0005506iron ion bindingIEA
GO:0016705oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygenIEA
GO:0020037heme bindingIEA
GeneCards CYP4F22
UniProt Q6NT55
Vega OTTHUMG00000182451
MIM 611495
Ensembl ENSG00000171954
HGNC 26820
HPRD 08256

Interactant

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