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HIST2H3C histone cluster 2, H3c [Homo sapiens (human)]


Clone ID RefSeq Accession Definition Vector Stock Status *Turnaround time Price Order
OHu13909 NM_021059 Homo sapiens histone cluster 2, H3c (HIST2H3C), mRNA. pcDNA3.1+-DYK In-stock 5-7 $99.00
OHu13909C NM_021059 Homo sapiens histone cluster 2, H3c (HIST2H3C), mRNA. Customized vector In-stock 5-7 $149.00

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Gene Symbol HIST2H3C
Entrez Gene ID 126961
Full Name histone cluster 2, H3c
Synonyms H3, H3.2, H3/M, H3F2, H3FM, H3FN
General protein information
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

1

1q21.2

Summary Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in a histone cluster on chromosome 1. This gene is one of four histone genes in the cluster that are duplicated; this record represents the telomeric copy. [provided by RefSeq, Jul 2008].
Disorder

MIM: 142780

mRNA Protein Product Sequence Price Select
NM_021059, 31742502 NP_066403, 31742503 histone H3.2 ORF Sequence $99.00
KEGG
hsa05322Systemic lupus erythematosus
hsa05202Transcriptional misregulation in cancer
hsa05034Alcoholism
WikiPathways
WP395IL-4 signaling Pathway
Reactome
REACT_152Cell Cycle, Mitotic
REACT_765Mitotic Prophase
REACT_910M Phase
REACT_71Gene Expression
REACT_604Hemostasis
REACT_11045Signaling by Wnt
REACT_2204RNA Polymerase I Chain Elongation
REACT_2232RNA Polymerase I Promoter Opening
REACT_1974RNA Polymerase I Promoter Clearance
REACT_1309RNA Polymerase I Transcription
REACT_21352RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription
REACT_27271Meiotic recombination
REACT_75925Amyloids
REACT_24970Factors involved in megakaryocyte development and platelet production
REACT_111183Meiosis
REACT_111102Signal Transduction
REACT_116125Disease
REACT_115566Cell Cycle
REACT_120956Cellular responses to stress
REACT_169168Senescence-Associated Secretory Phenotype (SASP)
REACT_169436Oxidative Stress Induced Senescence
REACT_169274Cellular Senescence
REACT_200808PRC2 methylates histones and DNA
REACT_200834Negative epigenetic regulation of rRNA expression
REACT_200827SIRT1 negatively regulates rRNA Expression
REACT_200857Epigenetic regulation of gene expression
REACT_200777TCF dependent signaling in response to WNT
REACT_200856NoRC negatively regulates rRNA expression
REACT_200753formation of the beta-catenin:TCF transactivating complex
REACT_172633Chromatin modifying enzymes
REACT_172610HATs acetylate histones
REACT_172744Condensation of Prophase Chromosomes
REACT_172623Chromatin organization
Homo sapiens (human)HIST2H3CNP_066403.2
Pan troglodytes (chimpanzee)LOC469476XP_524859.2
Macaca mulatta (Rhesus monkey)LOC710748XP_001109042.1
Canis lupus familiaris (dog)LOC100856221XP_003638893.1
Bos taurus (cattle)LOC781224XP_005208273.1
Mus musculus (house mouse)H3f3cXP_894986.1
Rattus norvegicus (Norway rat)H3f3cXP_003750396.1
Drosophila melanogaster (fruit fly)His3:CG33824NP_001027318.1
Xenopus (Silurana) tropicalis (western clawed frog)LOC100486720XP_002944964.1
GeneCards HIST2H3C
MIM 142780
HGNC 20503
HPRD 11822

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Interactant

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