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Sequence in raw or FASTA format:


Blast Method:


B3GALTL beta 1,3-galactosyltransferase-like [Homo sapiens (human)]

RefSeq Accession Definition Service Stock Status Price *Turnaround time Order
NM_194318 Homo sapiens beta 1,3-galactosyltransferase-like (B3GALTL), mRNA. GenEZ ORF Cloning On-demand $699.00 18
XM_006719768 PREDICTED: Homo sapiens beta 1,3-galactosyltransferase-like (B3GALTL), transcript variant X1, mRNA. GenEZ ORF Cloning On-demand $699.00 18

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Gene Symbol B3GALTL
Entrez Gene ID 145173
Full Name beta 1,3-galactosyltransferase-like
Synonyms B3GLCT, B3GTL, B3Glc-T, Gal-T, beta3Glc-T
General protein information
Preferred Names
beta 3-glycosyltransferase-like
UDP-GAL:beta-GlcNAc beta-1,3-galactosyltransferase-like
Gene Type protein-coding
Organism Homo sapiens (human)



Summary The protein encoded by this gene is a beta-1,3-glucosyltransferase that transfers glucose to O-linked fucosylglycans on thrombospondin type-1 repeats (TSRs) of several proteins. The encoded protein is a type II membrane protein. Defects in this gene are a cause of Peters-plus syndrome (PPS).[provided by RefSeq, Mar 2009].

MIM: 610308

Peters-plus syndrome, 261540 (3)

mRNA Protein Product Sequence Price Select
NM_194318, 154689816 NP_919299, 154689817 beta-1,3-glucosyltransferase precursor ORF Sequence $550.00
XM_006719768, 578824754 XP_006719831, 578824755 beta-1,3-glucosyltransferase isoform X1 ORF Sequence $550.00
hsa00514Other types of O-glycan biosynthesis
REACT_17015Metabolism of proteins
REACT_22161Post-translational protein modification
REACT_200727O-linked glycosylation
REACT_200626O-glycosylation of TSR domain-containing proteins
Homo sapiens (human)B3GALTLNP_919299.3
Pan troglodytes (chimpanzee)B3GALTLXP_509616.3
Canis lupus familiaris (dog)B3GALTLXP_543143.4
Mus musculus (house mouse)B3galtlNP_001074673.1
Rattus norvegicus (Norway rat)B3galtlXP_006248871.1
Gallus gallus (chicken)B3GALTLXP_004938819.1
Danio rerio (zebrafish)b3galtlbXP_692598.5
Drosophila melanogaster (fruit fly)CG9109NP_608982.2
Caenorhabditis elegansZC250.2NP_504520.2
Xenopus (Silurana) tropicalis (western clawed frog)b3galtlNP_001072551.1
GO:0006004fucose metabolic processIEA
GO:0006486protein glycosylationIEA
GO:0005789endoplasmic reticulum membraneIEA
GO:0016021integral component of membraneIEA
GO:0016757transferase activity, transferring glycosyl groupsIEA
GeneCards B3GALTL
UniProt Q6Y288
Vega OTTHUMG00000016688
MIM 610308
Ensembl ENSG00000187676
HGNC 20207
HPRD 12513

GeneRIFs: Gene References Into Functions What's a GeneRIF?

What is the normal function of the B3GALTL gene?

The B3GALTL gene provides instructions for making an enzyme called beta-1,3-glucosyltransferase (B3Glc-T), which is involved in the complex process of adding sugar molecules to proteins (glycosylation). Glycosylation modifies proteins so they can perform a wider variety of functions. The B3Glc-T enzyme is involved in a two-step glycosylation pathway that results in the formation of a sugar structure, made up of the sugars fucose and glucose, on a specific location of several different proteins. The B3Glc-T enzyme is responsible for the second step, which adds a glucose molecule to the fucose molecule already attached to the protein. The B3GALTL gene is normally turned on (active) in most cells of the body, which suggests that the B3Glc-T enzyme plays an important role across many cell types.


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