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CDAN1 codanin 1 [Homo sapiens (human)]


RefSeq Accession Definition Service Stock Status Price *Turnaround time Order
NM_138477 Homo sapiens codanin 1 (CDAN1), mRNA. GenEZ ORF Cloning On-demand TBD TBD
XM_005254176 PREDICTED: Homo sapiens codanin 1 (CDAN1), transcript variant X1, mRNA. GenEZ ORF Cloning On-demand TBD TBD
XM_005254177 PREDICTED: Homo sapiens codanin 1 (CDAN1), transcript variant X2, mRNA. GenEZ ORF Cloning On-demand TBD TBD
XM_005254178 PREDICTED: Homo sapiens codanin 1 (CDAN1), transcript variant X3, mRNA. GenEZ ORF Cloning On-demand TBD TBD

*Business Day

Related Services

Gene Symbol CDAN1
Entrez Gene ID 146059
Full Name codanin 1
Synonyms CDA1, CDAI, CDAN1A, DLT, PRO1295
General protein information
Preferred Names
codanin-1
Names
codanin-1
discs lost homolog
congenital dyserythropoietic anemia, type I
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

15

15q15.2

Summary This gene encodes a protein that appears to play a role in nuclear envelope integrity, possibly related to microtubule attachments. Mutations in this gene cause congenital dyserythropoietic anemia type I, a disease resulting in morphological and functional abnormalities of erythropoiesis. [provided by RefSeq, Jul 2009].
Disorder

MIM: 607465

Anemia, congenital dyserythropoietic, type I, 224120 (3)

mRNA Protein Product Sequence Price Select
NM_138477, 57222569 NP_612486, 57222570 codanin-1 ORF Sequence $1500.00
XM_005254176, 578826648 XP_005254233, 530405419 codanin-1 isoform X1 ORF Sequence $1500.00
XM_005254177, 530405420 XP_005254234, 530405421 codanin-1 isoform X2 ORF Sequence $1500.00
XM_005254178, 530405422 XP_005254235, 530405423 codanin-1 isoform X3 ORF Sequence $1500.00
Homo sapiens (human)CDAN1NP_612486.2
Pan troglodytes (chimpanzee)CDAN1XP_003952692.1
Macaca mulatta (Rhesus monkey)CDAN1XP_001105436.1
Canis lupus familiaris (dog)CDAN1XP_005638738.1
Bos taurus (cattle)CDAN1XP_002690857.1
Mus musculus (house mouse)Cdan1NP_081167.2
Rattus norvegicus (Norway rat)Cdan1XP_003749607.2
Gallus gallus (chicken)CDAN1XP_004941710.1
Danio rerio (zebrafish)cdan1XP_693684.6
Drosophila melanogaster (fruit fly)dltNP_728672.1
Xenopus (Silurana) tropicalis (western clawed frog)cdan1XP_002941131.2
Process
IDNameEvidence
GO:0006325chromatin organizationIMP
GO:0008104protein localizationIMP
GO:0008156negative regulation of DNA replicationIMP
GO:0031497chromatin assemblyIMP
Component
IDNameEvidence
GO:0005634nucleusIDA
GO:0005737cytoplasmIDA
GO:0005886plasma membraneIDA
GO:0012505endomembrane systemIDA
GO:0016021integral component of membraneIEA
Function
IDNameEvidence
GO:0005515protein bindingIPI
GeneCards CDAN1
UniProt Q8IWY9
Vega OTTHUMG00000175801
MIM 607465
Ensembl ENSG00000140326
HGNC 1713
HPRD 08470

GeneRIFs: Gene References Into Functions What's a GeneRIF?

What is the normal function of the CDAN1 gene?

The CDAN1 gene provides instructions for making a protein called codanin-1. Although this protein is active in cells throughout the body, very little is known about its function.

A recent study suggests that codanin-1 is associated with a form of DNA called heterochromatin. Heterochromatin is densely packed DNA that contains few functional genes, but it plays an important role in maintaining the structure of the nucleus (where most of the cell's DNA is located).

Researchers speculate that codanin-1 may be involved in the formation of red blood cells, a process called erythropoiesis. Specifically, this protein may play a key role in the organization of heterochromatin during the division of these developing cells.

Interactant

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