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Il10 interleukin 10 [Mus musculus (house mouse)]


RefSeq Accession Definition Sequence Price Select
NM_010548 Mus musculus interleukin 10 (Il10), mRNA. Full Length $378.74
ORF Sequence $159.00


Gene Symbol Il10
Entrez Gene ID 16153
Full Name interleukin 10
Synonyms CSIF, Il-10
Gene Type protein-coding
Organism Mus musculus (house mouse)
Genome

1

1 E4|1 69.9 cM
Summary
Disorder

MIM:

mRNA NM_010548, 291575143
Protein NP_034678, 6754318
Product interleukin-10 precursor
RefSeq Status VALIDATED
KEGG
mmu04060Cytokine-cytokine receptor interaction
mmu05310Asthma
mmu05144Malaria
mmu05142Chagas disease (American trypanosomiasis)
mmu04630Jak-STAT signaling pathway
mmu05330Allograft rejection
mmu05145Toxoplasmosis
mmu04672Intestinal immune network for IgA production
mmu05320Autoimmune thyroid disease
mmu05140Leishmaniasis
mmu05143African trypanosomiasis
mmu05146Amoebiasis
mmu05150Staphylococcus aureus infection
mmu04660T cell receptor signaling pathway
mmu05322Systemic lupus erythematosus
WikiPathways
WP222Cytokines and Inflammatory Response (BioCarta)
WP1266SIDS Susceptibility Pathways
Homo sapiens (human)IL10NP_000563.1
Pan troglodytes (chimpanzee)IL10XP_525040.1
Canis lupus familiaris (dog)IL10XP_855560.1
Bos taurus (cattle)IL10NP_776513.1
Mus musculus (house mouse)Il10NP_034678.1
Rattus norvegicus (Norway rat)Il10NP_036986.1
Gallus gallus (chicken)IL10NP_001004414.1
Danio rerio (zebrafish)il10NP_001018621.2
Danio rerio (zebrafish)LOC100331157XP_002663824.1
Process
IDNameEvidence
GO:0001818negative regulation of cytokine productionISO
GO:0002237response to molecule of bacterial originISO
GO:0002740negative regulation of cytokine secretion involved in immune responseISO
GO:0002875negative regulation of chronic inflammatory response to antigenic stimulusIMP
GO:0002904positive regulation of B cell apoptosisISO
GO:0006954inflammatory responseISO
GO:0006955immune responseISO
GO:0010468regulation of gene expressionISO
GO:0030886negative regulation of myeloid dendritic cell activationIMP
GO:0030889negative regulation of B cell proliferationISO
GO:0032689negative regulation of interferon-gamma productionIMP
GO:0032695negative regulation of interleukin-12 productionIMP
GO:0032715negative regulation of interleukin-6 productionISO
GO:0032720negative regulation of tumor necrosis factor productionIMP
GO:0032800receptor biosynthetic processISO
GO:0042536negative regulation of tumor necrosis factor biosynthetic processISO
GO:0042742defense response to bacteriumIDA
GO:0043066negative regulation of apoptosisISO
GO:0044130negative regulation of growth of symbiont in hostIMP
GO:0045019negative regulation of nitric oxide biosynthetic processISO
GO:0045348positive regulation of MHC class II biosynthetic processIDA
GO:0050715positive regulation of cytokine secretionISO
GO:0050728negative regulation of inflammatory responseISO
GO:0051045negative regulation of membrane protein ectodomain proteolysisISO
GO:0051091positive regulation of sequence-specific DNA binding transcription factor activityISO
GO:0051384response to glucocorticoid stimulusISO
GO:0051930regulation of sensory perception of painISO
GO:0060670branching involved in embryonic placenta morphogenesisIMP
Component
IDNameEvidence
GO:0005576extracellular regionISO
GO:0005615extracellular spaceIDA
GO:0005615extracellular spaceISO
Function
IDNameEvidence
GO:0005125cytokine activityIDA
GO:0005125cytokine activityIMP
GO:0005141interleukin-10 receptor bindingISO
GeneCards Il10
UniProt P18893, Q0VBJ1, Q3U879
MGI 96537
Ensembl ENSMUSG00000016529

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