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Sequence in raw or FASTA format:

Database:

Blast Method:

 
 


Il7r interleukin 7 receptor [Mus musculus (house mouse)]


RefSeq Accession Definition Services Price Order
NM_008372 Mus musculus interleukin 7 receptor (Il7r), mRNA. ORF Sequence $400.20
Peptide Services
Antibody Services
Protein Services


Gene Symbol Il7r
Entrez Gene ID 16197
Full Name interleukin 7 receptor
Synonyms CD127, IL-7Ralpha, MGC107557
Gene Type protein-coding
Organism Mus musculus (house mouse)
Genome

15

15 A1|15 4.6 cM

Summary Interleukin-7 is a glycoptorein involved in the regulation of lymphopoiesis. Response of cells to IL7 is dependent on the presence of the interleukin 7 receptor (IL7R); the active receptor is a alpha/gamma chain heterodimer. The gamma(c) chain, which also associates with the interleukin-2 receptor, serves primarily to activate signal transduction by the IL7R complex, while the alpha chain of IL7R determines specific signaling events through its association with cytoplasmic signaling molecules. [provided by RefSeq, Jul 2008].
Disorder

MIM:

mRNA Protein Product Sequence Price Select
NM_008372, 168480108 NP_032398, 45269152 interleukin-7 receptor subunit alpha precursor Full Length $1129.45
ORF Sequence $400.20
KEGG
mmu04060Cytokine-cytokine receptor interaction
mmu04630Jak-STAT signaling pathway
mmu04151PI3K-Akt signaling pathway
mmu04640Hematopoietic cell lineage
mmu05340Primary immunodeficiency
WikiPathways
WP297IL-7 Signaling Pathway
Reactome
2676132Signaling by Interleukins
2676018Immune System
2676133Cytokine Signaling in Immune system
2676824Interleukin-7 signaling
Homo sapiens (human)IL7RNP_002176.2
Pan troglodytes (chimpanzee)IL7RXP_517807.2
Macaca mulatta (Rhesus monkey)IL7RXP_001092582.1
Canis lupus familiaris (dog)IL7RXP_855408.1
Bos taurus (cattle)IL7RNP_001192816.1
Mus musculus (house mouse)Il7rNP_032398.3
Rattus norvegicus (Norway rat)Il7rNP_001099888.1
Gallus gallus (chicken)IL7RNP_001073575.1
GeneCards Il7r
UniProt Q8C9W4, Q5FW78, P16872
MGI 96562
Ensembl ENSMUSG00000003882

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

General protein information

Preferred Names
interleukin-7 receptor subunit alpha
Names
interleukin-7 receptor subunit alpha
IL-7RA
IL-7R-alpha
IL-7R subunit alpha
IL-7 receptor alpha chain
IL-7 receptor subunit alpha
interleukin 7 receptor alpha chain

Interactant

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