Atp6v0c ATPase, H+ transporting, lysosomal V0 subunit C [Rattus norvegicus (Norway rat)]
| Gene Symbol | Atp6v0c |
| Entrez Gene ID | 170667 |
| Full Name | ATPase, H+ transporting, lysosomal V0 subunit C |
| Synonyms | Atp6c, Atp6l |
| Gene Type | protein-coding |
| Organism | Rattus norvegicus (Norway rat) |
| Genome |
10 10q12 |
| Summary | subunit of vacuolar H(+)-ATPase [RGD]. |
| Disorder | MIM: |
| mRNA | NM_130823, 42475952 |
| Protein | NP_570836, 18677757 |
| Product | V-type proton ATPase 16 kDa proteolipid subunit |
| RefSeq Status | PROVISIONAL |
| rno00190 | Oxidative phosphorylation |
| rno04966 | Collecting duct acid secretion |
| rno04142 | Lysosome |
| rno04145 | Phagosome |
| rno01100 | Metabolic pathways |
| rno05323 | Rheumatoid arthritis |
Reactome
| 1235564 | Signaling by Insulin receptor |
| 1235567 | Insulin receptor recycling |
| Homo sapiens (human) | ATP6V0C | NP_001685.1 |
| Pan troglodytes (chimpanzee) | ATP6V0C | XP_510748.2 |
| Canis lupus familiaris (dog) | ATP6V0C | XP_864690.1 |
| Bos taurus (cattle) | ATP6V0C | NP_001017954.1 |
| Mus musculus (house mouse) | Atp6v0c | NP_033859.1 |
| Mus musculus (house mouse) | Atp6v0c-ps2 | XP_001473541.1 |
| Rattus norvegicus (Norway rat) | Atp6v0c | NP_570836.1 |
| Gallus gallus (chicken) | ATP6V0C | XP_001232268.1 |
| Danio rerio (zebrafish) | atp6v0cb | NP_991117.1 |
| Danio rerio (zebrafish) | atp6v0ca | NP_775362.1 |
| Drosophila melanogaster (fruit fly) | Vha16 | NP_724475.1 |
| Caenorhabditis elegans | vha-1 | NP_499165.1 |
| ID | Name | Evidence |
| GO:0006811 | ion transport | IEA |
| GO:0015986 | ATP synthesis coupled proton transport | IEA |
| GO:0015991 | ATP hydrolysis coupled proton transport | IEA |
Component
| ID | Name | Evidence |
| GO:0005764 | lysosome | IDA |
| GO:0005773 | vacuole | IEA |
| GO:0005774 | vacuolar membrane | IEA |
| GO:0005794 | Golgi apparatus | IDA |
| GO:0016020 | membrane | IEA |
| GO:0016021 | integral to membrane | IEA |
| GO:0033179 | proton-transporting V-type ATPase, V0 domain | IEA |
| GO:0045263 | proton-transporting ATP synthase complex, coupling factor F(o) | IEA |
Function
| ID | Name | Evidence |
| GO:0015078 | hydrogen ion transmembrane transporter activity | IEA |
| GO:0042625 | ATPase activity, coupled to transmembrane movement of ions | NAS |
| GeneCards | Atp6v0c |
| UniProt | P63081 |
| RGD | 621394 |
| Ensembl | ENSRNOG00000006542 |
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