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Abcc1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 [Mus musculus (house mouse)]


RefSeq Accession Definition Service Stock Status Price *Turnaround time Order
NM_008576 Mus musculus ATP-binding cassette, sub-family C (CFTR/MRP), member 1 (Abcc1), mRNA. GenEZ ORF Cloning In-stock $1598.00 $1549.00 22

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Gene Symbol Abcc1
Entrez Gene ID 17250
Full Name ATP-binding cassette, sub-family C (CFTR/MRP), member 1
Synonyms Abcc1a, Abcc1b, MRP, Mdrap, Mrp1
Gene Type protein-coding
Organism Mus musculus (house mouse)
Genome

16

16 A1|16

Summary The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. This protein plays an essential role in the defense against toxic compounds and serves as the major high-affinity transporter of leukotriene C4. The encoded protein may also play an essential role in steroid hormone homeostasis as a transporter for steroid hormones and their metabolites. [provided by RefSeq, Nov 2011].
Disorder

MIM:

mRNA Protein Product Sequence Price Select
NM_008576, 357430786 NP_032602, 6678848 multidrug resistance-associated protein 1 ORF Sequence $1399.00
KEGG
mmu04977Vitamin digestion and absorption
mmu02010ABC transporters
WikiPathways
WP475Irinotecan Pathway
Reactome
2675887Metabolism
2676621ABC-family proteins mediated transport
2675923Metabolism of lipids and lipoproteins
2676091Arachidonic acid metabolism
2675899Transmembrane transport of small molecules
Homo sapiens (human)ABCC1NP_004987.2
Pan troglodytes (chimpanzee)ABCC1XP_001145351.1
Canis lupus familiaris (dog)ABCC1NP_001002971.1
Bos taurus (cattle)ABCC1NP_776648.1
Mus musculus (house mouse)Abcc1NP_032602.1
Rattus norvegicus (Norway rat)Abcc1NP_071617.2
Gallus gallus (chicken)ABCC1NP_001012540.1
Danio rerio (zebrafish)abcc1XP_001341895.3
Caenorhabditis elegansmrp-1NP_741702.1
Caenorhabditis elegansmrp-2NP_508121.1
Arabidopsis thaliana (thale cress)MRP3NP_187915.1
Arabidopsis thaliana (thale cress)MRP8NP_187916.3
Arabidopsis thaliana (thale cress)MRP7NP_187917.3
GeneCards Abcc1
UniProt O35379, A5D6P3
MGI 102676
Ensembl ENSMUSG00000023088

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

General protein information

Preferred Names
multidrug resistance-associated protein 1
Names
multidrug resistance-associated protein 1
LTC4 transporter
leukotriene C(4) transporter
multiple drug resistance-associated protein
ATP-binding cassette, sub-family C (CFTR/MRP), member 1a
ATP-binding cassette, sub-family C (CFTR/MRP), member 1b

Interactant



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