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Sequence in raw or FASTA format:

Database:

Blast Method:

 
 


AGXT alanine-glyoxylate aminotransferase [Homo sapiens (human)]


RefSeq Accession Definition Services Price Order
NM_000030 Homo sapiens alanine-glyoxylate aminotransferase (AGXT), mRNA. ORF Sequence $341.91
Peptide Services
Antibody Services
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Gene Symbol AGXT
Entrez Gene ID 189
Full Name alanine-glyoxylate aminotransferase
Synonyms AGT, AGT1, AGXT1, PH1, SPAT, SPT, TLH6
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

2

2q37.3

Summary This gene is expressed only in the liver and the encoded protein is localized mostly in the peroxisomes, where it is involved in glyoxylate detoxification. Mutations in this gene, some of which alter subcellular targetting, have been associated with type I primary hyperoxaluria. [provided by RefSeq, Jul 2008].
Disorder

MIM: 604285

Hyperoxaluria, primary, type 1, 259900 (3)

mRNA Protein Product Sequence Price Select
NM_000030, 171906613 NP_000021, 4557289 serine--pyruvate aminotransferase Full Length $467.19
ORF Sequence $341.91
KEGG
hsa00250Alanine, aspartate and glutamate metabolism
hsa00630Glyoxylate and dicarboxylate metabolism
hsa04146Peroxisome
hsa00260Glycine, serine and threonine metabolism
WikiPathways
WP106Alanine and aspartate metabolism
BIOCYC
HUMAN_GLYSYN-ALA-PWYglycine biosynthesis III
Reactome
REACT_111217Metabolism
REACT_16925Glyoxylate metabolism
REACT_13Metabolism of amino acids and derivatives
Homo sapiens (human)AGXTNP_000021.1
Pan troglodytes (chimpanzee)AGXTXP_003309627.2
Macaca mulatta (Rhesus monkey)AGXTXP_001090301.2
Canis lupus familiaris (dog)LOC100855679XP_003639939.1
Canis lupus familiaris (dog)AGXTXP_848328.2
Bos taurus (cattle)AGXTNP_001095825.1
Mus musculus (house mouse)AgxtNP_057911.2
Rattus norvegicus (Norway rat)AgxtNP_085914.1
Gallus gallus (chicken)AGXTXP_003641783.1
Danio rerio (zebrafish)agxtaNP_001002331.1
Danio rerio (zebrafish)agxtbNP_998327.1
Drosophila melanogaster (fruit fly)SpatNP_511062.1
Caenorhabditis elegansT14D7.1NP_495885.1
Arabidopsis thaliana (thale cress)AGTNP_849951.1
GeneCards AGXT
PDB 1H0C, 3R9A, 1J04
UniProt P21549
MIM 604285
Ensembl ENSG00000172482
HGNC 341
HPRD 05048

GeneRIFs: Gene References Into Functions What's a GeneRIF?

General protein information

Interactant

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