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Ppara peroxisome proliferator activated receptor alpha [Mus musculus (house mouse)]


RefSeq Accession Definition Sequence Price Select
NM_011144 Mus musculus peroxisome proliferator activated receptor alpha (Ppara), transcript variant 1, mRNA. Full Length $3354.30
ORF Sequence $408.03
NM_001113418 Mus musculus peroxisome proliferator activated receptor alpha (Ppara), transcript variant 2, mRNA. Full Length $3247.20
ORF Sequence $408.03


Gene Symbol Ppara
Entrez Gene ID 19013
Full Name peroxisome proliferator activated receptor alpha
Synonyms 4933429D07Rik, AW742785, Nr1c1, PPAR-alpha, PPARalpha, Ppar
Gene Type protein-coding
Organism Mus musculus (house mouse)
Genome

15

15 E2|15 48.8 cM
Summary
Disorder

MIM:

mRNA NM_011144, 164663878
Protein NP_035274, 31543500
Product peroxisome proliferator-activated receptor alpha
RefSeq Status VALIDATED
mRNA NM_001113418, 164663879
Protein NP_001106889, 164663880
Product peroxisome proliferator-activated receptor alpha
RefSeq Status VALIDATED
KEGG
mmu03320PPAR signaling pathway
mmu05160Hepatitis C
mmu04920Adipocytokine signaling pathway
WikiPathways
WP447Adipogenesis
WP509Nuclear Receptors
WP431Nuclear receptors in lipid metabolism and toxicity
Reactome
1210763Generic Transcription Pathway
1210110Fatty acid, triacylglycerol, and ketone body metabolism
1210111Metabolism of lipids and lipoproteins
1210815Nuclear Receptor transcription pathway
1210887Regulation of Lipid Metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
1210129Gene Expression
Homo sapiens (human)PPARANP_001001928.1
Pan troglodytes (chimpanzee)PPARAXP_001136299.1
Canis lupus familiaris (dog)PPARANP_001003093.1
Bos taurus (cattle)PPARANP_001029208.1
Mus musculus (house mouse)PparaNP_035274.2
Rattus norvegicus (Norway rat)PparaNP_037328.1
Gallus gallus (chicken)PPARANP_001001464.1
Danio rerio (zebrafish)pparabNP_001096037.1
Process
IDNameEvidence
GO:0001666response to hypoxiaISO
GO:0006006glucose metabolic processTAS
GO:0006351transcription, DNA-dependentISO
GO:0006355regulation of transcription, DNA-dependentISO
GO:0006355regulation of transcription, DNA-dependentTAS
GO:0006629lipid metabolic processTAS
GO:0006631fatty acid metabolic processIMP
GO:0006631fatty acid metabolic processISO
GO:0006631fatty acid metabolic processTAS
GO:0007165signal transductionIDA
GO:0008544epidermis developmentIMP
GO:0010468regulation of gene expressionIMP
GO:0010745negative regulation of macrophage derived foam cell differentiationISO
GO:0010871negative regulation of receptor biosynthetic processISO
GO:0010887negative regulation of cholesterol storageISO
GO:0010891negative regulation of sequestering of triglycerideISO
GO:0019217regulation of fatty acid metabolic processIMP
GO:0032099negative regulation of appetiteIMP
GO:0032868response to insulin stimulusISO
GO:0042060wound healingIMP
GO:0042157lipoprotein metabolic processISO
GO:0043401steroid hormone mediated signaling pathwayISO
GO:0043401steroid hormone mediated signaling pathwayTAS
GO:0045776negative regulation of blood pressureISO
GO:0045893positive regulation of transcription, DNA-dependentIMP
GO:0045944positive regulation of transcription from RNA polymerase II promoterIDA
GO:0045944positive regulation of transcription from RNA polymerase II promoterIGI
GO:0046321positive regulation of fatty acid oxidationIMP
GO:0072363regulation of glycolysis by positive regulation of transcription from an RNA polymerase II promoterISO
GO:0072366regulation of cellular ketone metabolic process by positive regulation of transcription from an RNA polymerase II promoterISO
GO:0072369regulation of lipid transport by positive regulation of transcription from an RNA polymerase II promoterISO
Component
IDNameEvidence
GO:0005634nucleusISO
GO:0005634nucleusTAS
Function
IDNameEvidence
GO:0003677DNA bindingIDA
GO:0003700sequence-specific DNA binding transcription factor activityIMP
GO:0003700sequence-specific DNA binding transcription factor activityISO
GO:0003706ligand-regulated transcription factor activityISO
GO:0003707steroid hormone receptor activityISO
GO:0003707steroid hormone receptor activityTAS
GO:0004872receptor activityIDA
GO:0004879ligand-dependent nuclear receptor activityISO
GO:0005515protein bindingIPI
GO:0008144drug bindingISO
GO:0008270zinc ion bindingIEA
GO:0008289lipid bindingIDA
GO:0008289lipid bindingISO
GO:0019904protein domain specific bindingISO
GO:0031624ubiquitin conjugating enzyme bindingISO
GO:0043565sequence-specific DNA bindingIDA
GO:0046872metal ion bindingIEA
GO:0046982protein heterodimerization activityTAS
GO:0070215MDM2 bindingISO
GeneCards Ppara
UniProt P23204, Q542P9
MGI 104740
Ensembl ENSMUSG00000022383

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