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Ppara peroxisome proliferator activated receptor alpha [Mus musculus (house mouse)]


Clone ID RefSeq Accession Definition Vector Stock Status *Turnaround time Price Order
OMu22504 NM_011144 Mus musculus peroxisome proliferator activated receptor alpha (Ppara), transcript variant 1, mRNA. pcDNA3.1+-DYK On-demand 7-9 $219.00
OMu22504 NM_001113418 Mus musculus peroxisome proliferator activated receptor alpha (Ppara), transcript variant 2, mRNA. pcDNA3.1+-DYK On-demand 7-9 $219.00
OMu22504 XM_006520619 PREDICTED: Mus musculus peroxisome proliferator activated receptor alpha (Ppara), transcript variant X1, mRNA. pcDNA3.1+-DYK On-demand 7-9 $219.00
OMu22504 XM_006520620 PREDICTED: Mus musculus peroxisome proliferator activated receptor alpha (Ppara), transcript variant X2, mRNA. pcDNA3.1+-DYK On-demand 7-9 $219.00
OMu22504 XM_006520621 PREDICTED: Mus musculus peroxisome proliferator activated receptor alpha (Ppara), transcript variant X3, mRNA. pcDNA3.1+-DYK On-demand 7-9 $219.00
OMu22504 XM_006520622 PREDICTED: Mus musculus peroxisome proliferator activated receptor alpha (Ppara), transcript variant X4, mRNA. pcDNA3.1+-DYK On-demand 7-9 $219.00
OMu22504 XM_006520623 PREDICTED: Mus musculus peroxisome proliferator activated receptor alpha (Ppara), transcript variant X5, mRNA. pcDNA3.1+-DYK On-demand 7-9 $219.00
OMu51072 XM_006520624 PREDICTED: Mus musculus peroxisome proliferator activated receptor alpha (Ppara), transcript variant X6, mRNA. pcDNA3.1+-DYK On-demand 7-9 $219.00
OMu22504C NM_011144 Mus musculus peroxisome proliferator activated receptor alpha (Ppara), transcript variant 1, mRNA. Customized vector On-demand 7-9 $269.00
OMu22504C NM_001113418 Mus musculus peroxisome proliferator activated receptor alpha (Ppara), transcript variant 2, mRNA. Customized vector On-demand 7-9 $269.00
OMu22504C XM_006520619 PREDICTED: Mus musculus peroxisome proliferator activated receptor alpha (Ppara), transcript variant X1, mRNA. Customized vector On-demand 7-9 $269.00
OMu22504C XM_006520620 PREDICTED: Mus musculus peroxisome proliferator activated receptor alpha (Ppara), transcript variant X2, mRNA. Customized vector On-demand 7-9 $269.00
OMu22504C XM_006520621 PREDICTED: Mus musculus peroxisome proliferator activated receptor alpha (Ppara), transcript variant X3, mRNA. Customized vector On-demand 7-9 $269.00
OMu22504C XM_006520622 PREDICTED: Mus musculus peroxisome proliferator activated receptor alpha (Ppara), transcript variant X4, mRNA. Customized vector On-demand 7-9 $269.00
OMu22504C XM_006520623 PREDICTED: Mus musculus peroxisome proliferator activated receptor alpha (Ppara), transcript variant X5, mRNA. Customized vector On-demand 7-9 $269.00
OMu51072C XM_006520624 PREDICTED: Mus musculus peroxisome proliferator activated receptor alpha (Ppara), transcript variant X6, mRNA. Customized vector On-demand 7-9 $269.00

*Business Day

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Gene Symbol Ppara
Entrez Gene ID 19013
Full Name peroxisome proliferator activated receptor alpha
Synonyms 4933429D07Rik, AW742785, Nr1c1, PPAR-alpha, PPARalpha, Ppar
General protein information
Preferred Names
peroxisome proliferator-activated receptor alpha
Names
peroxisome proliferator-activated receptor alpha
nuclear receptor subfamily 1 group C member 1
Gene Type protein-coding
Organism Mus musculus (house mouse)
Genome

15

15 E2|15 40.42 cM

Summary
Disorder

MIM:

mRNA Protein Product Sequence Price Select
NM_001113418, 164663879 NP_001106889, 164663880 peroxisome proliferator-activated receptor alpha ORF Sequence $550.00
NM_011144, 164663878 NP_035274, 31543500 peroxisome proliferator-activated receptor alpha ORF Sequence $550.00
XM_006520619, 568991726 XP_006520682, 568991727 peroxisome proliferator-activated receptor alpha isoform X1 ORF Sequence $550.00
XM_006520620, 568991728 XP_006520683, 568991729 peroxisome proliferator-activated receptor alpha isoform X2 ORF Sequence $550.00
XM_006520621, 568991730 XP_006520684, 568991731 peroxisome proliferator-activated receptor alpha isoform X3 ORF Sequence $550.00
XM_006520622, 568991732 XP_006520685, 568991733 peroxisome proliferator-activated receptor alpha isoform X4 ORF Sequence $550.00
XM_006520623, 568991734 XP_006520686, 568991735 peroxisome proliferator-activated receptor alpha isoform X5 ORF Sequence $550.00
XM_006520624, 568991736 XP_006520687, 568991737 peroxisome proliferator-activated receptor alpha isoform X6 ORF Sequence $550.00
KEGG
mmu03320PPAR signaling pathway
mmu04920Adipocytokine signaling pathway
mmu05160Hepatitis C
mmu04932Non-alcoholic fatty liver disease (NAFLD)
WikiPathways
WP447Adipogenesis
WP509Nuclear Receptors
WP431Nuclear receptors in lipid metabolism and toxicity
WP2316PPAR signaling pathway
WP2309XPodNet - protein-protein interactions in the podocyte expanded by STRING
LIPID MAPS
PPARPPAR (Peroxisome proliferator-activated receptor) signaling pathway
Reactome
5334727Mus musculus biological processes
1368110Bmal1:Clock,Npas2 activates circadian gene expression
5605863Regulation of cholesterol biosynthesis by SREBP (SREBF)
5605862Activation of gene expression by SREBF (SREBP)
5605536Transcriptional regulation of white adipocyte differentiation
508751Circadian Clock
1368092Rora activates circadian gene expression
5605897YAP1- and WWTR1 (TAZ)-stimulated gene expression
5604990Transcriptional activation of mitochondrial biogenesis
5604992Organelle biogenesis and maintenance
5605592Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
5605593Circadian Clock
5605595RORA activates circadian gene expression
5605699BMAL1:CLOCK,NPAS2 activates circadian gene expression
5605594REV-ERBA represses gene expression
5605220Generic Transcription Pathway
5604991Mitochondrial biogenesis
5604683Metabolism of lipids and lipoproteins
5604644Metabolism
5604924Developmental Biology
5604682Fatty acid, triacylglycerol, and ketone body metabolism
5605700PPARA activates gene expression
5605517Nuclear Receptor transcription pathway
5604724Gene Expression
Homo sapiens (human)PPARANP_001001928.1
Pan troglodytes (chimpanzee)PPARAXP_001136470.1
Macaca mulatta (Rhesus monkey)PPARANP_001028201.1
Canis lupus familiaris (dog)PPARANP_001003093.1
Bos taurus (cattle)PPARANP_001029208.1
Mus musculus (house mouse)PparaNP_001106889.1
Rattus norvegicus (Norway rat)PparaNP_037328.1
Gallus gallus (chicken)PPARANP_001001464.1
Danio rerio (zebrafish)pparabNP_001096037.1
Danio rerio (zebrafish)LOC100534818XP_003201422.1
Xenopus (Silurana) tropicalis (western clawed frog)LOC100497346XP_002940784.2
Process
IDNameEvidence
GO:0000122negative regulation of transcription from RNA polymerase II promoterISO
GO:0001666response to hypoxiaISO
GO:0006006glucose metabolic processTAS
GO:0006351transcription, DNA-templatedIEA
GO:0006355regulation of transcription, DNA-templatedISO
GO:0006355regulation of transcription, DNA-templatedTAS
GO:0006366transcription from RNA polymerase II promoterIDA
GO:0006629lipid metabolic processTAS
GO:0006631fatty acid metabolic processIMP
GO:0006631fatty acid metabolic processISO
GO:0006631fatty acid metabolic processTAS
GO:0008544epidermis developmentIMP
GO:0010468regulation of gene expressionIMP
GO:0010745negative regulation of macrophage derived foam cell differentiationISO
GO:0010871negative regulation of receptor biosynthetic processISO
GO:0010887negative regulation of cholesterol storageISO
GO:0010891negative regulation of sequestering of triglycerideISO
GO:0019217regulation of fatty acid metabolic processIMP
GO:0030522intracellular receptor signaling pathwayISO
GO:0032091negative regulation of protein bindingISO
GO:0032099negative regulation of appetiteIMP
GO:0032868response to insulinISO
GO:0032922circadian regulation of gene expressionIDA
GO:0035095behavioral response to nicotineISO
GO:0042060wound healingIMP
GO:0042157lipoprotein metabolic processISO
GO:0042752regulation of circadian rhythmIDA
GO:0043401steroid hormone mediated signaling pathwayISO
GO:0045722positive regulation of gluconeogenesisIMP
GO:0045776negative regulation of blood pressureISO
GO:0045893positive regulation of transcription, DNA-templatedIMP
GO:0045893positive regulation of transcription, DNA-templatedISO
GO:0045944positive regulation of transcription from RNA polymerase II promoterIDA
GO:0045944positive regulation of transcription from RNA polymerase II promoterIGI
GO:0045944positive regulation of transcription from RNA polymerase II promoterIMP
GO:0045944positive regulation of transcription from RNA polymerase II promoterISO
GO:0046321positive regulation of fatty acid oxidationIMP
GO:0070166enamel mineralizationIMP
GO:0072363regulation of glycolytic by positive regulation of transcription from RNA polymerase II promoterISO
GO:0072366regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoterISO
GO:0072369regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoterISO
GO:1901215negative regulation of neuron deathISO
GO:2000678negative regulation of transcription regulatory region DNA bindingISO
Component
IDNameEvidence
GO:0005634nucleusISO
GO:0005634nucleusTAS
Function
IDNameEvidence
GO:0000978RNA polymerase II core promoter proximal region sequence-specific DNA bindingISO
GO:0001077RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcriptionISO
GO:0001078RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcriptionISO
GO:0001103RNA polymerase II repressing transcription factor bindingISO
GO:0001190RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcriptionIDA
GO:0003677DNA bindingIDA
GO:0003700sequence-specific DNA binding transcription factor activityIMP
GO:0003700sequence-specific DNA binding transcription factor activityISO
GO:0003707steroid hormone receptor activityISO
GO:0003707steroid hormone receptor activityTAS
GO:0004872receptor activityIDA
GO:0004879ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activityISO
GO:0005515protein bindingIPI
GO:0008144drug bindingISO
GO:0008270zinc ion bindingIEA
GO:0008289lipid bindingIDA
GO:0008289lipid bindingISO
GO:0019902phosphatase bindingISO
GO:0019904protein domain specific bindingISO
GO:0031624ubiquitin conjugating enzyme bindingISO
GO:0032403protein complex bindingISO
GO:0043565sequence-specific DNA bindingIDA
GO:0046872metal ion bindingIEA
GO:0046982protein heterodimerization activityTAS
GO:0051525NFAT protein bindingISO
GO:0097371MDM2/MDM4 family protein bindingISO
GeneCards Ppara
UniProt P23204, Q542P9
MGI 104740

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Interactant

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