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MEGF8 multiple EGF-like-domains 8 [Homo sapiens (human)]


Clone ID RefSeq Accession Definition Vector Stock Status *Turnaround time Price Order
OHu28623 NM_001410 Homo sapiens multiple EGF-like-domains 8 (MEGF8), transcript variant 2, mRNA. pcDNA3.1+-DYK On-demand 40 $4749.00
OHu28635 NM_001271938 Homo sapiens multiple EGF-like-domains 8 (MEGF8), transcript variant 1, mRNA. pcDNA3.1+-DYK On-demand 40 $4749.00
OHu28623C NM_001410 Homo sapiens multiple EGF-like-domains 8 (MEGF8), transcript variant 2, mRNA. Customized vector On-demand 40 $4749.00
OHu28635C NM_001271938 Homo sapiens multiple EGF-like-domains 8 (MEGF8), transcript variant 1, mRNA. Customized vector On-demand 40 $4749.00

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Gene Symbol MEGF8
Entrez Gene ID 1954
Full Name multiple EGF-like-domains 8
Synonyms C19orf49, CRPT2, EGFL4, SBP1
General protein information
Preferred Names
multiple epidermal growth factor-like domains protein 8
Names
multiple epidermal growth factor-like domains protein 8
EGF-like-domain, multiple 4
HBV pre-s2 binding protein 1
EGF-like domain-containing protein 4
epidermal growth factor-like protein 4
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

19

19q12

Summary The protein encoded by this gene is a single-pass type I membrane protein of unknown function that contains several EGF-like domains, Kelch repeats, and PSI domains. Defects in this gene are a cause of Carpenter syndrome 2. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2012].
Disorder

MIM: 604267

mRNA Protein Product Sequence Price Select
NM_001271938, 429836858 NP_001258867, 429836859 multiple epidermal growth factor-like domains protein 8 isoform 1 precursor ORF Sequence $4500.00
NM_001410, 145701024 NP_001401, 145701025 multiple epidermal growth factor-like domains protein 8 isoform 2 precursor ORF Sequence $4500.00
Homo sapiens (human)MEGF8NP_001258867.1
Pan troglodytes (chimpanzee)MEGF8XP_003316429.1
Macaca mulatta (Rhesus monkey)LOC709352XP_002808242.1
Canis lupus familiaris (dog)MEGF8XP_541588.5
Bos taurus (cattle)MEGF8XP_002695193.3
Mus musculus (house mouse)Megf8NP_001153872.1
Rattus norvegicus (Norway rat)Megf8NP_446080.1
Danio rerio (zebrafish)megf8XP_005158088.1
Drosophila melanogaster (fruit fly)CG7466NP_609180.2
Xenopus (Silurana) tropicalis (western clawed frog)megf8XP_002936442.2
Process
IDNameEvidence
GO:0003143embryonic heart tube morphogenesisISS
GO:0010468regulation of gene expressionISS
GO:0030326embryonic limb morphogenesisISS
GO:0030509BMP signaling pathwayISS
GO:0035108limb morphogenesisIMP
GO:0042074cell migration involved in gastrulationIMP
GO:0048704embryonic skeletal system morphogenesisISS
GO:0048842positive regulation of axon extension involved in axon guidanceISS
GO:0055113epiboly involved in gastrulation with mouth forming secondIMP
GO:0060971embryonic heart tube left/right pattern formationISS
GO:0060972left/right pattern formationIMP
GO:0061371determination of heart left/right asymmetryIMP
GO:0071907determination of digestive tract left/right asymmetryISS
GO:0097094craniofacial suture morphogenesisIMP
GO:0097155fasciculation of sensory neuron axonISS
Component
IDNameEvidence
GO:0005634nucleusISS
GO:0016021integral component of membraneIEA
GO:0070062extracellular vesicular exosomeIDA
Function
IDNameEvidence
GO:0004872receptor activityIEA
GO:0005509calcium ion bindingIEA
GO:0005515protein bindingIPI
GeneCards MEGF8
UniProt Q7Z7M0
Vega OTTHUMG00000150342
MIM 604267
Ensembl ENSG00000105429
HGNC 3233
HPRD 10370

Interactant

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