Ido2 indoleamine 2,3-dioxygenase 2 [Mus musculus (house mouse)]
| Gene Symbol | Ido2 |
| Entrez Gene ID | 209176 |
| Full Name | indoleamine 2,3-dioxygenase 2 |
| Synonyms | AI265623, C230043N17Rik, Indol1, MGC31194 |
| Gene Type | protein-coding |
| Organism | Mus musculus (house mouse) |
| Genome |
8 8 A2|8 |
| Summary | |
| Disorder | MIM: |
| mRNA | NM_145949, 170763487 |
| Protein | NP_666061, 170763488 |
| Product | indoleamine 2,3-dioxygenase 2 |
| RefSeq Status | VALIDATED |
| mmu05143 | African trypanosomiasis |
| mmu00380 | Tryptophan metabolism |
| mmu01100 | Metabolic pathways |
Reactome
| 1210094 | Metabolism of amino acids and derivatives |
| 1210117 | Tryptophan catabolism |
| Homo sapiens (human) | IDO2 | NP_919270.2 |
| Pan troglodytes (chimpanzee) | IDO2 | XP_528116.2 |
| Canis lupus familiaris (dog) | IDO2 | XP_539961.2 |
| Mus musculus (house mouse) | Ido2 | NP_666061.1 |
| Rattus norvegicus (Norway rat) | Ido2 | XP_001061228.1 |
| Gallus gallus (chicken) | INDOL1 | XP_424397.2 |
| Danio rerio (zebrafish) | ido1 | NP_001077323.1 |
| ID | Name | Evidence |
| GO:0019441 | tryptophan catabolic process to kynurenine | IDA |
| GO:0019441 | tryptophan catabolic process to kynurenine | IMP |
| GO:0019441 | tryptophan catabolic process to kynurenine | ISO |
| GO:0055114 | oxidation-reduction process | IDA |
| GO:0055114 | oxidation-reduction process | IEA |
| GO:0055114 | oxidation-reduction process | IMP |
| GO:0055114 | oxidation-reduction process | ISO |
Component
| ID | Name | Evidence |
| GO:0005737 | cytoplasm | IDA |
| GO:0005829 | cytosol | ISO |
Function
| ID | Name | Evidence |
| GO:0004833 | tryptophan 2,3-dioxygenase activity | ISO |
| GO:0016491 | oxidoreductase activity | IEA |
| GO:0016702 | oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen | IEA |
| GO:0020037 | heme binding | IEA |
| GO:0033754 | indoleamine 2,3-dioxygenase activity | IDA |
| GO:0033754 | indoleamine 2,3-dioxygenase activity | IMP |
| GO:0033754 | indoleamine 2,3-dioxygenase activity | ISO |
| GO:0046872 | metal ion binding | IEA |
| GeneCards | Ido2 |
| UniProt | E9QKA9, A4UHF3 |
| MGI | 2142489 |
| Ensembl | ENSMUSG00000031549 |
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