Tcf3 transcription factor 3 [Mus musculus (house mouse)]

Gene Symbol	Tcf3
Entrez Gene ID	21423
Full Name	transcription factor 3
Synonyms	A1, AA408400, ALF2, AW209082, E12, E12/E47, E2A, E47, ME2, Pan1, Pan2, Tcfe2a, VDIR, bHLHb21
Gene Type	protein-coding
Organism	Mus musculus (house mouse)
Genome	Chromosome:10 Map Location:10 C1\|10 43.0 cM
Summary
Disorder	MIM:

mRNA	NM_001164147, 255918152
Protein	NP_001157619, 255918153
Product	transcription factor E2-alpha isoform 1
RefSeq Status	VALIDATED
mRNA	NM_001164148, 255918155
Protein	NP_001157620, 255918156
Product	transcription factor E2-alpha isoform 2
RefSeq Status	VALIDATED
mRNA	NM_001164149, 255918157
Protein	NP_001157621, 255918158
Product	transcription factor E2-alpha isoform 3
RefSeq Status	VALIDATED
mRNA	NM_001164150, 255918159
Protein	NP_001157622, 255918160
Product	transcription factor E2-alpha isoform 4
RefSeq Status	VALIDATED
mRNA	NM_001164151, 255918161
Protein	NP_001157623, 255918162
Product	transcription factor E2-alpha isoform 5
RefSeq Status	VALIDATED
mRNA	NM_001164152, 255918163
Protein	NP_001157624, 255918164
Product	transcription factor E2-alpha isoform 6
RefSeq Status	VALIDATED
mRNA	NM_001164153, 255918165
Protein	NP_001157625, 255918166
Product	transcription factor E2-alpha isoform 7
RefSeq Status	VALIDATED
mRNA	NM_011548, 255918167
Protein	NP_035678, 255918168
Product	transcription factor E2-alpha isoform 8
RefSeq Status	VALIDATED

WikiPathways

WP512	Id Signaling Pathway
WP265	Delta-Notch Signaling Pathway
WP539	Wnt Signaling Pathway NetPath

Homo sapiens (human)	TCF3	NP_003191.1
Canis lupus familiaris (dog)	TCF3	XP_542197.2
Bos taurus (cattle)	TCF3	XP_609091.4
Mus musculus (house mouse)	Tcf3	NP_035678.2
Rattus norvegicus (Norway rat)	Tcfe2a	NP_001030314.1
Gallus gallus (chicken)	TCF3	NP_989817.2
Danio rerio (zebrafish)	zgc:113045	XP_694512.3

Process

ID	Name	Evidence
GO:0000080	G1 phase of mitotic cell cycle	ISO
GO:0001779	natural killer cell differentiation	IGI
GO:0002326	B cell lineage commitment	ISO
GO:0006351	transcription, DNA-dependent	ISO
GO:0006351	transcription, DNA-dependent	TAS
GO:0006355	regulation of transcription, DNA-dependent	IDA
GO:0006355	regulation of transcription, DNA-dependent	IGI
GO:0010628	positive regulation of gene expression	IMP
GO:0030098	lymphocyte differentiation	IMP
GO:0030890	positive regulation of B cell proliferation	ISO
GO:0032496	response to lipopolysaccharide	IMP
GO:0033077	T cell differentiation in thymus	IMP
GO:0033152	immunoglobulin V(D)J recombination	IMP
GO:0033152	immunoglobulin V(D)J recombination	ISO
GO:0042493	response to drug	IMP
GO:0043966	histone H3 acetylation	IMP
GO:0043967	histone H4 acetylation	IMP
GO:0045787	positive regulation of cell cycle	ISO
GO:0045893	positive regulation of transcription, DNA-dependent	ISO
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	IDA
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	IGI
GO:0048468	cell development	IGI
GO:0048541	Peyer's patch development	IGI
GO:0050821	protein stabilization	IDA
GO:0051149	positive regulation of muscle cell differentiation	ISO

Component

ID	Name	Evidence
GO:0000788	nuclear nucleosome	IDA
GO:0005634	nucleus	IDA
GO:0005634	nucleus	ISO
GO:0005654	nucleoplasm	ISO
GO:0005667	transcription factor complex	IDA
GO:0005667	transcription factor complex	ISO
GO:0005737	cytoplasm	ISO
GO:0043234	protein complex	ISO

Function

ID	Name	Evidence
GO:0003677	DNA binding	IDA
GO:0003677	DNA binding	ISO
GO:0003700	sequence-specific DNA binding transcription factor activity	ISO
GO:0003700	sequence-specific DNA binding transcription factor activity	TAS
GO:0005515	protein binding	IPI
GO:0008134	transcription factor binding	ISO
GO:0042802	identical protein binding	ISO
GO:0042803	protein homodimerization activity	IDA
GO:0042803	protein homodimerization activity	ISO
GO:0043425	bHLH transcription factor binding	ISO
GO:0043565	sequence-specific DNA binding	IDA
GO:0046982	protein heterodimerization activity	IPI
GO:0046982	protein heterodimerization activity	ISO
GO:0046983	protein dimerization activity	IPI
GO:0070644	vitamin D response element binding	ISO
GO:0070888	E-box binding	IDA
GO:0070888	E-box binding	ISO

RefSeq Accession	Definition	Sequence	Price	Select
NM_001164147	Mus musculus transcription factor 3 (Tcf3), transcript variant 1, mRNA.	Full Length	$1162.00
NM_001164147		ORF Sequence	$568.98
NM_001164148	Mus musculus transcription factor 3 (Tcf3), transcript variant 2, mRNA.	Full Length	$1160.95
NM_001164148		ORF Sequence	$568.11
NM_001164149	Mus musculus transcription factor 3 (Tcf3), transcript variant 3, mRNA.	Full Length	$1159.90
NM_001164149		ORF Sequence	$567.24
NM_001164150	Mus musculus transcription factor 3 (Tcf3), transcript variant 4, mRNA.	Full Length	$1158.85
NM_001164150		ORF Sequence	$566.37
NM_001164151	Mus musculus transcription factor 3 (Tcf3), transcript variant 5, mRNA.	Full Length	$1157.80
NM_001164151		ORF Sequence	$565.50
NM_001164152	Mus musculus transcription factor 3 (Tcf3), transcript variant 6, mRNA.	Full Length	$1157.80
NM_001164152		ORF Sequence	$565.50
NM_001164153	Mus musculus transcription factor 3 (Tcf3), transcript variant 7, mRNA.	Full Length	$1156.75
NM_001164153		ORF Sequence	$564.63
NM_011548	Mus musculus transcription factor 3 (Tcf3), transcript variant 8, mRNA.	Full Length	$1156.75
NM_011548		ORF Sequence	$564.63