• THAT   AND
  • THAT   AND


Sequence in raw or FASTA format:

Database:

Blast Method:

 
 


FANCD2 Fanconi anemia, complementation group D2 [Homo sapiens (human)]


RefSeq Accession Definition Service Stock Status Price *Turnaround time Order
NM_001018115 Homo sapiens Fanconi anemia, complementation group D2 (FANCD2), transcript variant 2, mRNA. GenEZ ORF Cloning On-demand $1699.00 25
NM_033084 Homo sapiens Fanconi anemia, complementation group D2 (FANCD2), transcript variant 1, mRNA. GenEZ ORF Cloning On-demand $1699.00 25

*Business Day

Related Services

Gene Symbol FANCD2
Entrez Gene ID 2177
Full Name Fanconi anemia, complementation group D2
Synonyms DKFZp762A223, FA-D2, FA4, FACD, FAD, FAD2, FANCD, FLJ23826
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

3

3p26

Summary The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group D2. This protein is monoubiquinated in response to DNA damage, resulting in its localization to nuclear foci with other proteins (BRCA1 AND BRCA2) involved in homology-directed DNA repair. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].
Disorder

MIM: 227646

Fanconi anemia, complementation group D2 (3)

mRNA Protein Product Sequence Price Select
NM_001018115, 66528887 NP_001018125, 66528888 Fanconi anemia group D2 protein isoform b ORF Sequence $1500.00
NM_033084, 66528797 NP_149075, 21361861 Fanconi anemia group D2 protein isoform a ORF Sequence $1500.00
KEGG
hsa03460Fanconi anemia pathway
WikiPathways
WP231TNF-alpha/NF-kB Signaling Pathway
WP707DNA damage response
Pathway Interaction Database
bard1pathwayBARD1 signaling events
Reactome
REACT_18265Regulation of the Fanconi anemia pathway
REACT_216DNA Repair
REACT_18410Fanconi Anemia pathway
Homo sapiens (human)FANCD2NP_001018125.1
Pan troglodytes (chimpanzee)FANCD2XP_003309761.1
Macaca mulatta (Rhesus monkey)LOC716070XP_002803125.1
Canis lupus familiaris (dog)FANCD2XP_541774.2
Bos taurus (cattle)FANCD2NP_001179358.1
Mus musculus (house mouse)Fancd2NP_001028416.2
Rattus norvegicus (Norway rat)Fancd2NP_001001719.1
Gallus gallus (chicken)FANCD2NP_001034350.1
Danio rerio (zebrafish)fancd2NP_958498.1
Drosophila melanogaster (fruit fly)Fancd2NP_996246.1
Arabidopsis thaliana (thale cress)AT4G14970NP_193233.5
GeneCards FANCD2
UniProt Q9BXW9
MIM 227646
Ensembl ENSG00000144554
HGNC 3585
HPRD 01968

GeneRIFs: Gene References Into Functions What's a GeneRIF?

General protein information

Preferred Names
Fanconi anemia group D2 protein
Names
Fanconi anemia group D2 protein

Interactant



Our customer service representatives are available 24 hours a day, Monday through Friday; please contact us anytime for assistance.

Learn more about the GenEZ ORF Cloning Service.