Sequence in raw or FASTA format:
CLCA4 chloride channel accessory 4 [Homo sapiens (human)]
| Gene Symbol | CLCA4 |
| Entrez Gene ID | 22802 |
| Full Name | chloride channel accessory 4 |
| Synonyms | CaCC, CaCC2, MGC142247, MGC142249 |
| Gene Type | protein-coding |
| Organism | Homo sapiens (human) |
| Genome |
1 1p31-p22 |
| Summary | The protein encoded by this gene belongs to the calcium sensitive chloride conductance protein family. To date, all members of this gene family map to the same site on chromosome 1p31-p22 and share high degrees of homology in size, sequence and predicted structure, but differ significantly in their tissue distributions. Alternative splicing results in multiple transcript variants, only one of which is thought to be protein coding. [provided by RefSeq]. |
| Disorder | MIM: |
| mRNA | NM_012128, 150036261 |
| Protein | NP_036260, 150036262 |
| Product | calcium-activated chloride channel regulator 4 |
| RefSeq Status | REVIEWED |
| Homo sapiens (human) | CLCA4 | NP_036260.2 |
| Pan troglodytes (chimpanzee) | CLCA4 | XP_524757.2 |
| Canis lupus familiaris (dog) | CLCA4 | XP_855328.1 |
| Bos taurus (cattle) | CLCA4 | NP_001029472.1 |
| Mus musculus (house mouse) | AI747448 | NP_001028371.1 |
| Mus musculus (house mouse) | Clca6 | NP_997091.3 |
| Rattus norvegicus (Norway rat) | Clca4 | NP_958822.1 |
| ID | Name | Evidence |
| GO:0006810 | transport | IEA |
| GO:0006821 | chloride transport | TAS |
Component
| ID | Name | Evidence |
| GO:0005576 | extracellular region | IEA |
| GO:0005886 | plasma membrane | IEA |
| GO:0005887 | integral to plasma membrane | TAS |
| GO:0016324 | apical plasma membrane | IEA |
Function
| ID | Name | Evidence |
| GO:0005254 | chloride channel activity | TAS |
| GeneCards | CLCA4 |
| UniProt | Q14CN2 |
| Ensembl | ENSG00000016602 |
| HGNC | 2018 |
| HPRD | 16719 |
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