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AAK1 AP2 associated kinase 1 [Homo sapiens (human)]


RefSeq Accession Definition Service Stock Status Price *Turnaround time Order
NM_014911 Homo sapiens AP2 associated kinase 1 (AAK1), mRNA. GenEZ ORF Cloning On-demand $899.00 20

*Business Day

Related Services

Gene Symbol AAK1
Entrez Gene ID 22848
Full Name AP2 associated kinase 1
Synonyms DKFZp686F03202, DKFZp686K16132, FLJ23712, FLJ25931, FLJ31060, FLJ42882, FLJ45252, KIAA1048, MGC138170, MGC164568, MGC164570
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

2

2p14

Summary Adaptor-related protein complex 2 (AP-2 complexes) functions during receptor-mediated endocytosis to trigger clathrin assembly, interact with membrane-bound receptors, and recruit encodytic accessory factors. This gene encodes a member of the SNF1 subfamily of Ser/Thr protein kinases. The protein interacts with and phosphorylates a subunit of the AP-2 complex, which promotes binding of AP-2 to sorting signals found in membrane-bound receptors and subsequent receptor endocytosis. Its kinase activity is stimulated by clathrin. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008].
Disorder

MIM:

mRNA Protein Product Sequence Price Select
NM_014911, 148277036 NP_055726, 148277037 AP2-associated protein kinase 1 ORF Sequence $750.00
Homo sapiens (human)AAK1NP_055726.3
Pan troglodytes (chimpanzee)AAK1XP_001138187.3
Canis lupus familiaris (dog)AAK1XP_531855.3
Bos taurus (cattle)AAK1XP_002691487.2
Mus musculus (house mouse)Aak1NP_001035195.1
GeneCards AAK1
UniProt Q2M2I8
Ensembl ENSG00000115977
HGNC 19679
HPRD 10620

General protein information

Preferred Names
AP2-associated protein kinase 1
Names
AP2-associated protein kinase 1
adaptor-associated kinase 1
NP_055726.3

Interactant



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