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MACF1 microtubule-actin crosslinking factor 1 [Homo sapiens (human)]


RefSeq Accession Definition Services Price Order
NM_012090 Homo sapiens microtubule-actin crosslinking factor 1 (MACF1), transcript variant 1, mRNA. ORF Sequence Quote
Peptide Services
Antibody Services
Protein Services


Gene Symbol MACF1
Entrez Gene ID 23499
Full Name microtubule-actin crosslinking factor 1
Synonyms ABP620, ACF7, FLJ45612, FLJ46776, KIAA0465, KIAA1251, MACF, OFC4
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

1

1p32-p31

Summary The protein encoded by this gene belongs to the plakin family of cytoskeletal linker proteins. This protein family forms bridges between different cytoskeletal elements through specialized modular domains. The encoded protein is one of the largest size proteins identified in human cytoskeletal proteins. It has functional actin and microtubule binding domains, and it appears to stabilize actin at sites where microtubules and microfilaments meet. It may function in microtubule dynamics to facilitate actin-microtubule interactions at the cell periphery and to couple the microtubule network to cellular junctions. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008].
Disorder

MIM: 608271

mRNA Protein Product Sequence Price Select
NM_012090, 325120977 NP_036222, 33188445 microtubule-actin cross-linking factor 1 isoform a Full Length $0.00
ORF Sequence $0.00
Homo sapiens (human)MACF1NP_036222.3
Pan troglodytes (chimpanzee)MACF1XP_001170702.1
Canis lupus familiaris (dog)MACF1XP_849152.1
Bos taurus (cattle)MACF1NP_001137332.1
Rattus norvegicus (Norway rat)Macf1NP_001129230.1
Gallus gallus (chicken)MACF1NP_001239050.1
Danio rerio (zebrafish)macf1XP_003200667.1
GeneCards MACF1
UniProt Q6ZSD7, Q9UPN3
MIM 608271
Ensembl ENSG00000127603
HGNC 13664
HPRD 09750

GeneRIFs: Gene References Into Functions What's a GeneRIF?

General protein information

Preferred Names
microtubule-actin cross-linking factor 1
Names
microtubule-actin cross-linking factor 1
macrophin 1
trabeculin-alpha
620 kDa actin binding protein
actin cross-linking family protein 7

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