• THAT   AND
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Sequence in raw or FASTA format:

Database:

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Slc17a5 solute carrier family 17 (anion/sugar transporter), member 5 [Mus musculus (house mouse)]


RefSeq Accession Definition Service Stock Status Price *Turnaround time Order
NM_001276452 Mus musculus solute carrier family 17 (anion/sugar transporter), member 5 (Slc17a5), transcript variant 2, mRNA. GenEZ ORF Cloning In-stock $509.00 $460.00 12
NM_172773 Mus musculus solute carrier family 17 (anion/sugar transporter), member 5 (Slc17a5), transcript variant 1, mRNA. GenEZ ORF Cloning On-demand $699.00 18
XM_006511128 PREDICTED: Mus musculus solute carrier family 17 (anion/sugar transporter), member 5 (Slc17a5), transcript variant X1, mRNA. GenEZ ORF Cloning On-demand $699.00 18
XM_006511129 PREDICTED: Mus musculus solute carrier family 17 (anion/sugar transporter), member 5 (Slc17a5), transcript variant X2, mRNA. GenEZ ORF Cloning On-demand $449.00 14

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Gene Symbol Slc17a5
Entrez Gene ID 235504
Full Name solute carrier family 17 (anion/sugar transporter), member 5
Synonyms 4631416G20Rik, 4732491M05, AST, ISSD, NSD, SD, SIALIN, SIASD, SLD
General protein information
Gene Type protein-coding
Organism Mus musculus (house mouse)
Genome

9

9 E1|9

Summary
Disorder

MIM:

mRNA Protein Product Sequence Price Select
NM_001276452, 451172070 NP_001263381, 451172071 sialin isoform b ORF Sequence $360.00
NM_172773, 451172069 NP_766361, 27370146 sialin isoform a ORF Sequence $550.00
XM_006511128, 568961400 XP_006511191, 568961401 sialin isoform X1 ORF Sequence $550.00
XM_006511129, 568961403 XP_006511192, 568961404 sialin isoform X2 ORF Sequence $300.00
KEGG
mmu04142Lysosome
Reactome
5604658SLC-mediated transmembrane transport
5605489Organic anion transporters
5605638Sialic acid metabolism
5605127Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
5605128Asparagine N-linked glycosylation
5605126Synthesis of substrates in N-glycan biosythesis
5604659Transmembrane transport of small molecules
5605477Transport of inorganic cations/anions and amino acids/oligopeptides
5605117Post-translational protein modification
Homo sapiens (human)SLC17A5NP_036566.1
Pan troglodytes (chimpanzee)SLC17A5XP_003311453.1
Macaca mulatta (Rhesus monkey)SLC17A5XP_001112868.1
Canis lupus familiaris (dog)SLC17A5XP_005627590.1
Bos taurus (cattle)SLC17A5NP_001192903.1
Mus musculus (house mouse)Slc17a5NP_766361.1
Rattus norvegicus (Norway rat)Slc17a5NP_001009713.1
Gallus gallus (chicken)SLC17A5NP_001026257.1
Danio rerio (zebrafish)slc17a5NP_001070195.1
Drosophila melanogaster (fruit fly)MFS10NP_572857.1
Caenorhabditis elegansC38C10.2NP_499065.1
Xenopus (Silurana) tropicalis (western clawed frog)slc17a5NP_001072823.1
Process
IDNameEvidence
GO:0006810transportIEA
GO:0006865amino acid transportIEA
GO:0015739sialic acid transportISO
GO:0034220ion transmembrane transportISO
GO:0055085transmembrane transportIEA
Component
IDNameEvidence
GO:0005737cytoplasmISO
GO:0005764lysosomeISO
GO:0005765lysosomal membraneISO
GO:0005886plasma membraneIDA
GO:0005886plasma membraneISO
GO:0016020membraneIEA
GO:0016021integral component of membraneIEA
GO:0016023cytoplasmic membrane-bounded vesicleIDA
GO:0030054cell junctionIEA
GO:0031410cytoplasmic vesicleIEA
GO:0045202synapseIEA
Function
IDNameEvidence
GO:0015136sialic acid transmembrane transporter activityISO
GO:0015293symporter activityIEA
GeneCards Slc17a5
UniProt Q8BN82
MGI 1924105
Vega OTTMUSG00000030755
Ensembl ENSMUSG00000049624
Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (Reporter) (1)¬†

What is the normal function of the SLC17A5 gene?

The SLC17A5 gene provides instructions for producing a protein called sialin that is located mainly on the membranes of lysosomes, compartments in the cell that digest and recycle materials. Sialin moves a molecule called free sialic acid, which is produced when certain proteins and fats are broken down, out of the lysosomes to other parts of the cell. Free sialic acid means that the sialic acid is not attached (bound) to other molecules.

Researchers believe that sialin may also have other functions in brain cells, in addition to those associated with the lysosomes, but these additional functions are not well understood.

Interactant

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