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Sequence in raw or FASTA format:

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CBLC Cas-Br-M (murine) ecotropic retroviral transforming sequence c [Homo sapiens (human)]


RefSeq Accession Definition Services Price Order
NM_001130852 Homo sapiens Cbl proto-oncogene, E3 ubiquitin protein ligase C (CBLC), transcript variant 2, mRNA. ORF Sequence $373.23
Peptide Services
Antibody Services
Protein Services
NM_012116 Homo sapiens Cbl proto-oncogene, E3 ubiquitin protein ligase C (CBLC), transcript variant 1, mRNA. ORF Sequence $413.25
Peptide Services
Antibody Services
Protein Services


Gene Symbol CBLC
Entrez Gene ID 23624
Full Name Cas-Br-M (murine) ecotropic retroviral transforming sequence c
Synonyms CBL-3, CBL-SL, RNF57
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

19

19q13.2

Summary This gene encodes a member of the Cbl family of E3 ubiquitin ligases. Cbl proteins play important roles in cell signaling through the ubiquitination and subsequent downregulation of tyrosine kinases. Expression of this gene may be restricted to epithelial cells, and alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2012].
Disorder

MIM: 608453

mRNA Protein Product Sequence Price Select
NM_001130852, 195927029 NP_001124324, 195927030 signal transduction protein CBL-C isoform 2 Full Length $421.37
ORF Sequence $373.23
NM_012116, 195927026 NP_036248, 195927027 signal transduction protein CBL-C isoform 1 Full Length $461.39
ORF Sequence $413.25
KEGG
hsa04012ErbB signaling pathway
hsa04660T cell receptor signaling pathway
hsa05100Bacterial invasion of epithelial cells
hsa05220Chronic myeloid leukemia
hsa04910Insulin signaling pathway
hsa04144Endocytosis
hsa04120Ubiquitin mediated proteolysis
hsa04630Jak-STAT signaling pathway
hsa05200Pathways in cancer
WikiPathways
WP437EGFR1 Signaling Pathway
WP481Insulin Signaling
WP673ErbB signaling pathway
Homo sapiens (human)CBLCNP_036248.3
Macaca mulatta (Rhesus monkey)CBLCXP_001109370.1
Canis lupus familiaris (dog)CBLCXP_855171.3
Bos taurus (cattle)CBLCNP_001094718.1
Mus musculus (house mouse)CblcNP_075713.3
Rattus norvegicus (Norway rat)CblcNP_001030092.1
GeneCards CBLC
PDB 3OP0, 3VRO, 3VRQ, 3VRP, 3VRN, 3VRR
UniProt Q9ULV8
MIM 608453
Ensembl ENSG00000142273
HGNC 15961
HPRD 09765

GeneRIFs: Gene References Into Functions What's a GeneRIF?

General protein information

Preferred Names
signal transduction protein CBL-C
Names
signal transduction protein CBL-C
RING finger protein 57
SH3-binding protein CBL-3
SH3-binding protein CBL-C
Cbl proto-oncogene, E3 ubiquitin protein ligase C
Cas-Br-M (murine) ectropic retroviral transforming sequence c
Cas-Br-M (murine) ecotropic retroviral transforming sequence c

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