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Sequence in raw or FASTA format:

Database:

Blast Method:

 
 


Klrk1 killer cell lectin-like receptor subfamily K, member 1 [Rattus norvegicus (Norway rat)]


RefSeq Accession Definition Service Stock Status Price *Turnaround time Order
NM_133512 Rattus norvegicus killer cell lectin-like receptor subfamily K, member 1 (Klrk1), mRNA. GenEZ ORF Cloning On-demand $399.00 14
XM_006237073 PREDICTED: Rattus norvegicus killer cell lectin-like receptor subfamily K, member 1 (Klrk1), transcript variant X1, mRNA. GenEZ ORF Cloning On-demand $399.00 14
XM_006237074 PREDICTED: Rattus norvegicus killer cell lectin-like receptor subfamily K, member 1 (Klrk1), transcript variant X2, mRNA. GenEZ ORF Cloning On-demand $399.00 14
XM_006237075 PREDICTED: Rattus norvegicus killer cell lectin-like receptor subfamily K, member 1 (Klrk1), transcript variant X3, mRNA. GenEZ ORF Cloning On-demand $399.00 14
XM_006237076 PREDICTED: Rattus norvegicus killer cell lectin-like receptor subfamily K, member 1 (Klrk1), transcript variant X4, mRNA. GenEZ ORF Cloning On-demand $399.00 14
XM_006237077 PREDICTED: Rattus norvegicus killer cell lectin-like receptor subfamily K, member 1 (Klrk1), transcript variant X5, mRNA. GenEZ ORF Cloning On-demand $399.00 14

*Business Day

Related Services

Gene Symbol Klrk1
Entrez Gene ID 24934
Full Name killer cell lectin-like receptor subfamily K, member 1
Synonyms NKG2D, Nkrp2
General protein information
Preferred Names
NKG2-D type II integral membrane protein
Names
NKG2-D type II integral membrane protein
NKLLR
NK cell receptor D
NK lectin-like receptor
NKG2-D-activating NK receptor
NKR-P2, ortholog of human NKG2D
Gene Type protein-coding
Organism Rattus norvegicus (Norway rat)
Genome

4

4q42

Summary functions as a natural cytotoxicity receptor to stimulate perforin-mediated elimination of ligand-expressing tumor cells [RGD, Feb 2006].
Disorder

MIM:

mRNA Protein Product Sequence Price Select
NM_133512, 397529589 NP_598196, 19424150 NKG2-D type II integral membrane protein ORF Sequence $250.00
XM_006237073, 564348311 XP_006237135, 564348312 NKG2-D type II integral membrane protein isoform X1 ORF Sequence $250.00
XM_006237074, 564348313 XP_006237136, 564348314 NKG2-D type II integral membrane protein isoform X2 ORF Sequence $250.00
XM_006237075, 564348315 XP_006237137, 564348316 NKG2-D type II integral membrane protein isoform X3 ORF Sequence $250.00
XM_006237076, 564348317 XP_006237138, 564348318 NKG2-D type II integral membrane protein isoform X4 ORF Sequence $250.00
XM_006237077, 564348319 XP_006237139, 564348320 NKG2-D type II integral membrane protein isoform X5 ORF Sequence $250.00
KEGG
rno04650Natural killer cell mediated cytotoxicity
rno05144Malaria
Reactome
5658215Immune System
5658213DAP12 interactions
5658212DAP12 signaling
5658214Innate Immune System
Pan troglodytes (chimpanzee)KLRK1NP_001009059.1
Macaca mulatta (Rhesus monkey)NKG2DNP_001028061.1
Canis lupus familiaris (dog)KLRK1XP_005637217.1
Bos taurus (cattle)KLRK1NP_001068607.1
Mus musculus (house mouse)Klrk1NP_149069.1
Rattus norvegicus (Norway rat)Klrk1NP_598196.1
Process
IDNameEvidence
GO:0002223stimulatory C-type lectin receptor signaling pathwayIEA
GO:0002223stimulatory C-type lectin receptor signaling pathwayISO
GO:0030101natural killer cell activationIEA
GO:0030101natural killer cell activationISO
GO:0030154cell differentiationIEA
GO:0032729positive regulation of interferon-gamma productionIEA
GO:0032729positive regulation of interferon-gamma productionISO
GO:0045087innate immune responseIEA
GO:0045429positive regulation of nitric oxide biosynthetic processIEA
GO:0045429positive regulation of nitric oxide biosynthetic processISO
GO:0045954positive regulation of natural killer cell mediated cytotoxicityISO
GO:0045954positive regulation of natural killer cell mediated cytotoxicityISS
GO:0050830defense response to Gram-positive bacteriumIEA
GO:0050830defense response to Gram-positive bacteriumISO
GO:0071222cellular response to lipopolysaccharideIEA
GO:0071222cellular response to lipopolysaccharideISO
Component
IDNameEvidence
GO:0009897external side of plasma membraneIEA
GO:0009897external side of plasma membraneISO
GO:0009986cell surfaceISO
GO:0009986cell surfaceISS
GO:0016021integral component of membraneIEA
Function
IDNameEvidence
GO:0019900kinase bindingISO
GO:0030246carbohydrate bindingIEA
GO:0032394MHC class Ib receptor activityIEA
GO:0032394MHC class Ib receptor activityISO
GO:0042288MHC class I protein bindingIEA
GO:0042288MHC class I protein bindingISO
GO:0042803protein homodimerization activityIEA
GO:0042803protein homodimerization activityISO
GeneCards Klrk1
UniProt O70215
RGD 3180
Ensembl ENSRNOG00000009638

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Interactant

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