PTPN20B protein tyrosine phosphatase, non-receptor type 20B [Homo sapiens (human)]
| Gene Symbol | PTPN20B |
| Entrez Gene ID | 26095 |
| Full Name | protein tyrosine phosphatase, non-receptor type 20B |
| Synonyms | DKFZp566K0524, DKFZp781P23155, bA42B19.1 |
| Gene Type | protein-coding |
| Organism | Homo sapiens (human) |
| Genome |
10 10q11.22 |
| Summary | The product of this gene belongs to the family of classical tyrosine-specific protein tyrosine phosphatases. Many protein tyrosine phosphatases have been shown to regulate fundamental cellular processes and several are mutated in human diseases. Chromosome 10q contains a segmental duplication resulting in multiple copies of the protein tyrosine phosphatase, non-receptor type 20 gene. The two nearly identical copies are designated as PTPN20A and PTPN20B. A third copy is only partially duplicated and contains a pseudogene, designated as PTPN20C. This gene encodes the more telomeric copy, PTPN20B. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq]. |
| Disorder | MIM: 610631 |
| mRNA | NM_001042358, 109633034 |
| Protein | NP_001035817, 108802607 |
| Product | protein tyrosine phosphatase, non-receptor type 20 isoform 3 |
| RefSeq Status | REVIEWED |
| mRNA | NM_001042365, 109138576 |
| Protein | NP_001035824, 108802621 |
| Product | protein tyrosine phosphatase, non-receptor type 20 isoform 10 |
| RefSeq Status | REVIEWED |
| mRNA | NM_001042360, 109138581 |
| Protein | NP_001035819, 108802611 |
| Product | protein tyrosine phosphatase, non-receptor type 20 isoform 5 |
| RefSeq Status | REVIEWED |
| mRNA | NM_001042364, 109633037 |
| Protein | NP_001035823, 108802619 |
| Product | protein tyrosine phosphatase, non-receptor type 20 isoform 9 |
| RefSeq Status | REVIEWED |
| mRNA | NM_001042363, 109633036 |
| Protein | NP_001035822, 108802617 |
| Product | protein tyrosine phosphatase, non-receptor type 20 isoform 8 |
| RefSeq Status | REVIEWED |
| mRNA | NM_015605, 109633032 |
| Protein | NP_056420, 45243554 |
| Product | protein tyrosine phosphatase, non-receptor type 20 isoform 2 |
| RefSeq Status | REVIEWED |
| mRNA | NM_001042357, 109633033 |
| Protein | NP_001035816, 108802604 |
| Product | protein tyrosine phosphatase, non-receptor type 20 isoform 1 |
| RefSeq Status | REVIEWED |
| mRNA | NM_001042361, 109633035 |
| Protein | NP_001035820, 108802613 |
| Product | protein tyrosine phosphatase, non-receptor type 20 isoform 6 |
| RefSeq Status | REVIEWED |
| mRNA | NM_001042362, 109138579 |
| Protein | NP_001035821, 108802615 |
| Product | protein tyrosine phosphatase, non-receptor type 20 isoform 7 |
| RefSeq Status | REVIEWED |
| mRNA | NM_001042359, 109138582 |
| Protein | NP_001035818, 108802609 |
| Product | protein tyrosine phosphatase, non-receptor type 20 isoform 4 |
| RefSeq Status | REVIEWED |
| Homo sapiens (human) | PTPN20B | NP_001035816.1 |
| Homo sapiens (human) | PTPN20A | NP_001035848.1 |
| Pan troglodytes (chimpanzee) | PTPN20A | XP_001136909.1 |
| Bos taurus (cattle) | LOC517883 | XP_001788066.1 |
| Mus musculus (house mouse) | Ptpn20 | NP_033004.1 |
| Rattus norvegicus (Norway rat) | Ptpn20 | XP_224639.4 |
| Arabidopsis thaliana (thale cress) | PTP1 | NP_177331.1 |
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