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MAGEA2B melanoma antigen family A, 2B [Homo sapiens (human)]


RefSeq Accession Definition Service Stock Status Price *Turnaround time Order
NM_153488 Homo sapiens melanoma antigen family A, 2B (MAGEA2B), mRNA. GenEZ ORF Cloning In-stock $348.00 $299.00 10
XM_005277836 PREDICTED: Homo sapiens melanoma antigen family A, 2B (MAGEA2B), transcript variant X2, mRNA. GenEZ ORF Cloning On-demand $449.00 14
XM_005277838 PREDICTED: Homo sapiens melanoma antigen family A, 2B (MAGEA2B), transcript variant X4, mRNA. GenEZ ORF Cloning On-demand $449.00 14
XM_005277839 PREDICTED: Homo sapiens melanoma antigen family A, 2B (MAGEA2B), transcript variant X5, mRNA. GenEZ ORF Cloning On-demand $449.00 14
XM_006724814 PREDICTED: Homo sapiens melanoma antigen family A, 2B (MAGEA2B), transcript variant X6, mRNA. GenEZ ORF Cloning On-demand $449.00 14

*Business Day

Related Services

Gene Symbol MAGEA2B
Entrez Gene ID 266740
Full Name melanoma antigen family A, 2B
Synonyms MAGE2, MAGEA2
General protein information
Preferred Names
melanoma-associated antigen 2
Names
melanoma-associated antigen 2
CT1.2
MAGE-2 antigen
melanoma antigen 2
cancer/testis antigen 1.2
melanoma antigen, family A, 2, copy b
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

X

Xq28

Summary This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. This gene has two identical copies at different loci. [provided by RefSeq, Jul 2008].
Disorder

MIM: 300549

mRNA Protein Product Sequence Price Select
NM_153488, 34335237 NP_705692, 24308498 melanoma-associated antigen 2 ORF Sequence $199.00
XM_005277836, 530430477 XP_005277893, 530430478 melanoma-associated antigen 2 isoform X2 ORF Sequence $300.00
XM_005277838, 578838837 XP_005277895, 530430482 melanoma-associated antigen 2 isoform X4 ORF Sequence $300.00
XM_005277839, 530430483 XP_005277896, 530430484 melanoma-associated antigen 2 isoform X5 ORF Sequence $300.00
XM_006724814, 578838838 XP_006724877, 578838839 melanoma-associated antigen 2 isoform X6 ORF Sequence $300.00
Homo sapiens (human)MAGEA2NP_001269434.1
Homo sapiens (human)MAGEA2BNP_705692.1
Pan troglodytes (chimpanzee)MAGEA2XP_003318187.1
Macaca mulatta (Rhesus monkey)MAGEA2XP_001095272.1
Process
IDNameEvidence
GO:0000122negative regulation of transcription from RNA polymerase II promoterIDA
GO:0006351transcription, DNA-templatedIEA
GO:0033234negative regulation of protein sumoylationIDA
GO:0044257cellular protein catabolic processIMP
GO:0051443positive regulation of ubiquitin-protein transferase activityIMP
GO:0072331signal transduction by p53 class mediatorIDA
GO:0090398cellular senescenceIDA
GO:1901984negative regulation of protein acetylationIDA
Component
IDNameEvidence
GO:0005634nucleusIDA
GO:0016605PML bodyIDA
Function
IDNameEvidence
GO:0005515protein bindingIPI
GO:0031625ubiquitin protein ligase bindingIDA
GO:0042826histone deacetylase bindingIDA
GO:0070491repressing transcription factor bindingIDA
GeneCards MAGEA2B
UniProt Q96E03
MIM 300549
HGNC 19340
HPRD 14347

Interactant

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