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ABL2 v-abl Abelson murine leukemia viral oncogene homolog 2 [Homo sapiens (human)]


RefSeq Accession Definition Service Stock Status Price *Turnaround time Order
NM_001136000 Homo sapiens v-abl Abelson murine leukemia viral oncogene homolog 2 (ABL2), transcript variant d, mRNA. GenEZ ORF Cloning On-demand $1699.00 25
NM_001136001 Homo sapiens v-abl Abelson murine leukemia viral oncogene homolog 2 (ABL2), transcript variant e, mRNA. GenEZ ORF Cloning On-demand $699.00 18
NM_001168236 Homo sapiens v-abl Abelson murine leukemia viral oncogene homolog 2 (ABL2), transcript variant f, mRNA. GenEZ ORF Cloning On-demand $1699.00 25
NM_001168237 Homo sapiens v-abl Abelson murine leukemia viral oncogene homolog 2 (ABL2), transcript variant g, mRNA. GenEZ ORF Cloning On-demand $1699.00 25
NM_001168238 Homo sapiens v-abl Abelson murine leukemia viral oncogene homolog 2 (ABL2), transcript variant h, mRNA. GenEZ ORF Cloning On-demand $1699.00 25
NM_001168239 Homo sapiens v-abl Abelson murine leukemia viral oncogene homolog 2 (ABL2), transcript variant i, mRNA. GenEZ ORF Cloning On-demand $1699.00 25
NM_005158 Homo sapiens v-abl Abelson murine leukemia viral oncogene homolog 2 (ABL2), transcript variant c, mRNA. GenEZ ORF Cloning On-demand $1699.00 25
NM_007314 Homo sapiens v-abl Abelson murine leukemia viral oncogene homolog 2 (ABL2), transcript variant b, mRNA. GenEZ ORF Cloning On-demand $1699.00 25

*Business Day

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Gene Symbol ABL2
Entrez Gene ID 27
Full Name v-abl Abelson murine leukemia viral oncogene homolog 2
Synonyms ABLL, ARG, FLJ22224, FLJ31718, FLJ41441
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

1

1q25.2

Summary This gene encodes a member of the Abelson family of nonreceptor tyrosine protein kinases. The protein is highly similar to the c-abl oncogene 1 protein, including the tyrosine kinase, SH2 and SH3 domains, and it plays a role in cytoskeletal rearrangements through its C-terminal F-actin- and microtubule-binding sequences. This gene is expressed in both normal and tumor cells, and is involved in translocation with the ets variant 6 gene in leukemia. Multiple alternatively spliced transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq, Nov 2009].
Disorder

MIM: 164690

Leukemia, acute myeloid, with eosinophilia (1)

mRNA Protein Product Sequence Price Select
NM_001136000, 269847772 NP_001129472, 209862772 Abelson tyrosine-protein kinase 2 isoform d ORF Sequence $1500.00
NM_001136001, 209862777 NP_001129473, 209862778 Abelson tyrosine-protein kinase 2 isoform e ORF Sequence $550.00
NM_001168236, 269847775 NP_001161708, 269847776 Abelson tyrosine-protein kinase 2 isoform f ORF Sequence $1500.00
NM_001168237, 269847780 NP_001161709, 269847781 Abelson tyrosine-protein kinase 2 isoform g ORF Sequence $1500.00
NM_001168238, 269847785 NP_001161710, 269847786 Abelson tyrosine-protein kinase 2 isoform h ORF Sequence $1500.00
NM_001168239, 269847792 NP_001161711, 269847793 Abelson tyrosine-protein kinase 2 isoform i ORF Sequence $1500.00
NM_005158, 269847767 NP_005149, 269847768 Abelson tyrosine-protein kinase 2 isoform c ORF Sequence $1500.00
NM_007314, 209862798 NP_009298, 6382062 Abelson tyrosine-protein kinase 2 isoform b ORF Sequence $1500.00
KEGG
hsa05416Viral myocarditis
hsa04012ErbB signaling pathway
Reactome
REACT_19351Signaling by Robo receptor
REACT_18266Axon guidance
REACT_19230Role of Abl in Robo-Slit signaling
REACT_111045Developmental Biology
Homo sapiens (human)ABL2NP_009298.1
Pan troglodytes (chimpanzee)ABL2XP_003308662.1
Macaca mulatta (Rhesus monkey)ABL2XP_001115453.2
Canis lupus familiaris (dog)ABL2XP_537174.2
Bos taurus (cattle)ABL2NP_001137327.1
Mus musculus (house mouse)Abl2NP_033725.2
Rattus norvegicus (Norway rat)Abl2NP_001100656.1
Gallus gallus (chicken)ABL2XP_422269.3
Danio rerio (zebrafish)abl2NP_001116177.1
GeneCards ABL2
PDB 3ULR, 3HMI, 2KK1, 2ECD, 2XYN, 3GVU
UniProt P42684
MIM 164690
Ensembl ENSG00000143322
HGNC 77
HPRD 01259

GeneRIFs: Gene References Into Functions What's a GeneRIF?

General protein information

Preferred Names
Abelson tyrosine-protein kinase 2
Names
Abelson tyrosine-protein kinase 2
tyrosine-protein kinase ARG
abelson-related gene protein
v-abl Abelson murine leukemia viral oncogene homolog 2
NP_001129472.1
NP_001129473.1
NP_001161708.1
NP_001161709.1
NP_001161710.1
NP_001161711.1
NP_005149.4
NP_009298.1

Interactant



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