Search Tips

  • THAT   AND
  • THAT   AND


Sequence in raw or FASTA format:

Database:

Blast Method:

 
 


Klrk1 killer cell lectin-like receptor subfamily K, member 1 [Mus musculus (house mouse)]


RefSeq Accession Definition Sequence Price Select
NM_033078 Mus musculus killer cell lectin-like receptor subfamily K, member 1 (Klrk1), transcript variant 1, mRNA. Full Length $1141.70
ORF Sequence $202.71
NM_001083322 Mus musculus killer cell lectin-like receptor subfamily K, member 1 (Klrk1), transcript variant 2, mRNA. Full Length $1105.30
ORF Sequence $191.40


Gene Symbol Klrk1
Entrez Gene ID 27007
Full Name killer cell lectin-like receptor subfamily K, member 1
Synonyms D6H12S2489E, NKG2-D, Nkg2d
Gene Type protein-coding
Organism Mus musculus (house mouse)
Genome

6

6 F3|6 62.53 cM
Summary
Disorder

MIM:

mRNA NM_033078, 134023659
Protein NP_149069, 14861840
Product NKG2-D type II integral membrane protein isoform a
RefSeq Status VALIDATED
mRNA NM_001083322, 134023657
Protein NP_001076791, 134023658
Product NKG2-D type II integral membrane protein isoform b
RefSeq Status VALIDATED
KEGG
mmu04650Natural killer cell mediated cytotoxicity
Reactome
1210700Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
1210312Signaling in Immune system
Homo sapiens (human)KLRK1NP_031386.2
Pan troglodytes (chimpanzee)KLRK1NP_001009059.1
Canis lupus familiaris (dog)KLRK1XP_854106.1
Bos taurus (cattle)KLRK1NP_001068607.1
Mus musculus (house mouse)Klrk1NP_149069.1
Rattus norvegicus (Norway rat)Klrk1NP_598196.1
Process
IDNameEvidence
GO:0002223stimulatory C-type lectin receptor signaling pathwayIMP
GO:0030101natural killer cell activationIMP
GO:0030101natural killer cell activationIPI
GO:0032729positive regulation of interferon-gamma productionIDA
GO:0045429positive regulation of nitric oxide biosynthetic processIDA
GO:0045954positive regulation of natural killer cell mediated cytotoxicityIMP
GO:0050830defense response to Gram-positive bacteriumIDA
GO:0071222cellular response to lipopolysaccharideIDA
Component
IDNameEvidence
GO:0009897external side of plasma membraneIDA
GO:0009986cell surfaceIDA
GO:0016020membraneIEA
GO:0016021integral to membraneIEA
Function
IDNameEvidence
GO:0004872receptor activityIEA
GO:0005488bindingIEA
GO:0005515protein bindingIPI
GO:0005529sugar bindingIEA
GO:0032394MHC class Ib receptor activityIMP
GO:0042288MHC class I protein bindingIPI
GO:0042803protein homodimerization activityIDA
GO:0045233natural killer cell receptor activityISO
GeneCards Klrk1
PDB 1JSK, 1HQ8
UniProt O54709, Q4FJM0
MGI 1196250
Ensembl ENSMUSG00000030149

Our customer service representatives are available 24 hours a day, Monday through Friday; please contact us anytime for assistance.

Secured Online Quotation
Email: gene@genscript.com
Phone: 1-877-436-7274 (Toll-Free) 1-732-885-9188
Fax: 1-732-210-0262 1-732-885-5878