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Sequence in raw or FASTA format:

Database:

Blast Method:

 
 


DISC1 disrupted in schizophrenia 1 [Homo sapiens (human)]


Clone ID RefSeq Accession Definition Vector Stock Status *Turnaround time Price Order
OHu24731 NM_001164555 Homo sapiens disrupted in schizophrenia 1 (DISC1), transcript variant r, mRNA. pcDNA3.1+-DYK On-demand TBD TBD
OHu24750 NM_001164540 Homo sapiens disrupted in schizophrenia 1 (DISC1), transcript variant d, mRNA. pcDNA3.1+-DYK On-demand TBD TBD
OHu24760 NM_001164545 Homo sapiens disrupted in schizophrenia 1 (DISC1), transcript variant h, mRNA. pcDNA3.1+-DYK On-demand TBD TBD
OHu24804 NM_001012959 Homo sapiens disrupted in schizophrenia 1 (DISC1), transcript variant S, mRNA. pcDNA3.1+-DYK On-demand TBD TBD
OHu24838 NM_001164551 Homo sapiens disrupted in schizophrenia 1 (DISC1), transcript variant n, mRNA. pcDNA3.1+-DYK On-demand TBD TBD
OHu24840 NM_001164546 Homo sapiens disrupted in schizophrenia 1 (DISC1), transcript variant i, mRNA. pcDNA3.1+-DYK On-demand TBD TBD
OHu24842 NM_001164541 Homo sapiens disrupted in schizophrenia 1 (DISC1), transcript variant e, mRNA. pcDNA3.1+-DYK On-demand TBD TBD
OHu24863 NM_001164538 Homo sapiens disrupted in schizophrenia 1 (DISC1), transcript variant b, mRNA. pcDNA3.1+-DYK On-demand TBD TBD
OHu24867 NM_001164553 Homo sapiens disrupted in schizophrenia 1 (DISC1), transcript variant p, mRNA. pcDNA3.1+-DYK On-demand TBD TBD
OHu24871 NM_001164549 Homo sapiens disrupted in schizophrenia 1 (DISC1), transcript variant l, mRNA. pcDNA3.1+-DYK On-demand TBD TBD
OHu24884 NM_001164550 Homo sapiens disrupted in schizophrenia 1 (DISC1), transcript variant m, mRNA. pcDNA3.1+-DYK On-demand TBD TBD
OHu24906 NM_018662 Homo sapiens disrupted in schizophrenia 1 (DISC1), transcript variant L, mRNA. pcDNA3.1+-DYK On-demand TBD TBD
OHu24928 NM_001164552 Homo sapiens disrupted in schizophrenia 1 (DISC1), transcript variant o, mRNA. pcDNA3.1+-DYK On-demand TBD TBD
OHu24938 NM_001164539 Homo sapiens disrupted in schizophrenia 1 (DISC1), transcript variant c, mRNA. pcDNA3.1+-DYK On-demand TBD TBD
OHu24941 NM_001164554 Homo sapiens disrupted in schizophrenia 1 (DISC1), transcript variant q, mRNA. pcDNA3.1+-DYK On-demand TBD TBD
OHu24840 NM_001164547 Homo sapiens disrupted in schizophrenia 1 (DISC1), transcript variant j, mRNA. pcDNA3.1+-DYK On-demand TBD TBD
OHu24946 NM_001164544 Homo sapiens disrupted in schizophrenia 1 (DISC1), transcript variant g, mRNA. pcDNA3.1+-DYK On-demand TBD TBD
OHu24960 NM_001012957 Homo sapiens disrupted in schizophrenia 1 (DISC1), transcript variant Lv, mRNA. pcDNA3.1+-DYK On-demand TBD TBD
OHu25023 NM_001164548 Homo sapiens disrupted in schizophrenia 1 (DISC1), transcript variant k, mRNA. pcDNA3.1+-DYK On-demand TBD TBD
OHu25031 NM_001164542 Homo sapiens disrupted in schizophrenia 1 (DISC1), transcript variant f, mRNA. pcDNA3.1+-DYK On-demand TBD TBD
OHu25035 NM_001012958 Homo sapiens disrupted in schizophrenia 1 (DISC1), transcript variant Es, mRNA. pcDNA3.1+-DYK On-demand TBD TBD
OHu25070 NM_001164556 Homo sapiens disrupted in schizophrenia 1 (DISC1), transcript variant t, mRNA. pcDNA3.1+-DYK On-demand TBD TBD
OHu25088 NM_001164537 Homo sapiens disrupted in schizophrenia 1 (DISC1), transcript variant a, mRNA. pcDNA3.1+-DYK On-demand TBD TBD
OHu24731C NM_001164555 Homo sapiens disrupted in schizophrenia 1 (DISC1), transcript variant r, mRNA. Customized vector On-demand TBD $269.00
OHu24750C NM_001164540 Homo sapiens disrupted in schizophrenia 1 (DISC1), transcript variant d, mRNA. Customized vector On-demand TBD $329.00
OHu24760C NM_001164545 Homo sapiens disrupted in schizophrenia 1 (DISC1), transcript variant h, mRNA. Customized vector On-demand TBD $269.00
OHu24804C NM_001012959 Homo sapiens disrupted in schizophrenia 1 (DISC1), transcript variant S, mRNA. Customized vector On-demand TBD $329.00
OHu24838C NM_001164551 Homo sapiens disrupted in schizophrenia 1 (DISC1), transcript variant n, mRNA. Customized vector On-demand TBD $269.00
OHu24840C NM_001164546 Homo sapiens disrupted in schizophrenia 1 (DISC1), transcript variant i, mRNA. Customized vector On-demand TBD $269.00
OHu24842C NM_001164541 Homo sapiens disrupted in schizophrenia 1 (DISC1), transcript variant e, mRNA. Customized vector On-demand TBD $329.00
OHu24863C NM_001164538 Homo sapiens disrupted in schizophrenia 1 (DISC1), transcript variant b, mRNA. Customized vector On-demand TBD $329.00
OHu24867C NM_001164553 Homo sapiens disrupted in schizophrenia 1 (DISC1), transcript variant p, mRNA. Customized vector On-demand TBD $269.00
OHu24871C NM_001164549 Homo sapiens disrupted in schizophrenia 1 (DISC1), transcript variant l, mRNA. Customized vector On-demand TBD $269.00
OHu24884C NM_001164550 Homo sapiens disrupted in schizophrenia 1 (DISC1), transcript variant m, mRNA. Customized vector On-demand TBD $269.00
OHu24906C NM_018662 Homo sapiens disrupted in schizophrenia 1 (DISC1), transcript variant L, mRNA. Customized vector On-demand TBD $329.00
OHu24928C NM_001164552 Homo sapiens disrupted in schizophrenia 1 (DISC1), transcript variant o, mRNA. Customized vector On-demand TBD $269.00
OHu24938C NM_001164539 Homo sapiens disrupted in schizophrenia 1 (DISC1), transcript variant c, mRNA. Customized vector On-demand TBD $329.00
OHu24941C NM_001164554 Homo sapiens disrupted in schizophrenia 1 (DISC1), transcript variant q, mRNA. Customized vector On-demand TBD $269.00
OHu24840C NM_001164547 Homo sapiens disrupted in schizophrenia 1 (DISC1), transcript variant j, mRNA. Customized vector On-demand TBD $269.00
OHu24946C NM_001164544 Homo sapiens disrupted in schizophrenia 1 (DISC1), transcript variant g, mRNA. Customized vector On-demand TBD $269.00
OHu24960C NM_001012957 Homo sapiens disrupted in schizophrenia 1 (DISC1), transcript variant Lv, mRNA. Customized vector On-demand TBD $329.00
OHu25023C NM_001164548 Homo sapiens disrupted in schizophrenia 1 (DISC1), transcript variant k, mRNA. Customized vector On-demand TBD $269.00
OHu25031C NM_001164542 Homo sapiens disrupted in schizophrenia 1 (DISC1), transcript variant f, mRNA. Customized vector On-demand TBD $329.00
OHu25035C NM_001012958 Homo sapiens disrupted in schizophrenia 1 (DISC1), transcript variant Es, mRNA. Customized vector On-demand TBD $269.00
OHu25070C NM_001164556 Homo sapiens disrupted in schizophrenia 1 (DISC1), transcript variant t, mRNA. Customized vector On-demand TBD $209.00
OHu25088C NM_001164537 Homo sapiens disrupted in schizophrenia 1 (DISC1), transcript variant a, mRNA. Customized vector On-demand TBD $329.00

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Gene Symbol DISC1
Entrez Gene ID 27185
Full Name disrupted in schizophrenia 1
Synonyms C1orf136, SCZD9
General protein information
Preferred Names
disrupted in schizophrenia 1 protein
Names
disrupted in schizophrenia 1 protein
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

1

1q42.1

Summary This gene encodes a protein with multiple coiled coil motifs which is located in the nucleus, cytoplasm and mitochondria. The protein is involved in neurite outgrowth and cortical development through its interaction with other proteins. This gene is disrupted in a t(1;11)(q42.1;q14.3) translocation which segregates with schizophrenia and related psychiatric disorders in a large Scottish family. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008].
Disorder

MIM: 605210

{Schizophrenia, susceptibility to}, 604906 (3); {Schizoaffective

mRNA Protein Product Sequence Price Select
NM_001012957, 61742824 NP_001012975, 61742825 disrupted in schizophrenia 1 protein isoform Lv ORF Sequence $750.00
NM_001012958, 61742826 NP_001012976, 61742827 disrupted in schizophrenia 1 protein isoform Es ORF Sequence $400.00
NM_001012959, 61742828 NP_001012977, 61742829 disrupted in schizophrenia 1 protein isoform S ORF Sequence $700.00
NM_001164537, 257153458 NP_001158009, 257153459 disrupted in schizophrenia 1 protein isoform a ORF Sequence $750.00
NM_001164538, 257153460 NP_001158010, 257153461 disrupted in schizophrenia 1 protein isoform b ORF Sequence $750.00
NM_001164539, 257153462 NP_001158011, 257153463 disrupted in schizophrenia 1 protein isoform c ORF Sequence $700.00
NM_001164540, 257153464 NP_001158012, 257153465 disrupted in schizophrenia 1 protein isoform d ORF Sequence $700.00
NM_001164541, 257153466 NP_001158013, 257153467 disrupted in schizophrenia 1 protein isoform e ORF Sequence $700.00
NM_001164542, 257153468 NP_001158014, 257153469 disrupted in schizophrenia 1 protein isoform f ORF Sequence $700.00
NM_001164544, 257153471 NP_001158016, 257153472 disrupted in schizophrenia 1 protein isoform g ORF Sequence $700.00
NM_001164545, 257153473 NP_001158017, 257153474 disrupted in schizophrenia 1 protein isoform h ORF Sequence $700.00
NM_001164546, 257153475 NP_001158018, 257153476 disrupted in schizophrenia 1 protein isoform i ORF Sequence $550.00
NM_001164547, 257153477 NP_001158019, 257153478 disrupted in schizophrenia 1 protein isoform i ORF Sequence $550.00
NM_001164548, 257153479 NP_001158020, 257153480 disrupted in schizophrenia 1 protein isoform k ORF Sequence $550.00
NM_001164549, 257153481 NP_001158021, 257153482 disrupted in schizophrenia 1 protein isoform l ORF Sequence $550.00
NM_001164550, 257153292 NP_001158022, 257153293 disrupted in schizophrenia 1 protein isoform m ORF Sequence $550.00
NM_001164551, 257153294 NP_001158023, 257153295 disrupted in schizophrenia 1 protein isoform n ORF Sequence $550.00
NM_001164552, 257153296 NP_001158024, 257153297 disrupted in schizophrenia 1 protein isoform o ORF Sequence $400.00
NM_001164553, 257153298 NP_001158025, 257153299 disrupted in schizophrenia 1 protein isoform p ORF Sequence $400.00
NM_001164554, 257153300 NP_001158026, 257153301 disrupted in schizophrenia 1 protein isoform q ORF Sequence $400.00
NM_001164555, 257153302 NP_001158027, 257153303 disrupted in schizophrenia 1 protein isoform r ORF Sequence $400.00
NM_001164556, 257153304 NP_001158028, 257153305 disrupted in schizophrenia 1 protein isoform t ORF Sequence $250.00
NM_018662, 61742822 NP_061132, 61742823 disrupted in schizophrenia 1 protein isoform L ORF Sequence $750.00
Homo sapiens (human)DISC1NP_001158009.1
Pan troglodytes (chimpanzee)DISC1XP_003308861.1
Macaca mulatta (Rhesus monkey)DISC1NP_001107827.1
Canis lupus familiaris (dog)DISC1XP_546088.3
Bos taurus (cattle)DISC1XP_002698851.2
Mus musculus (house mouse)Disc1NP_777279.2
Rattus norvegicus (Norway rat)Disc1NP_783186.2
Gallus gallus (chicken)DISC1XP_003641003.2
Process
IDNameEvidence
GO:0000226microtubule cytoskeleton organizationIMP
GO:0001764neuron migrationIMP
GO:0002052positive regulation of neuroblast proliferationIGI
GO:0008104protein localizationIEA
GO:0010975regulation of neuron projection developmentIEA
GO:0021799cerebral cortex radially oriented cell migrationIEA
GO:0021846cell proliferation in forebrainIEA
GO:0030177positive regulation of Wnt signaling pathwayIGI
GO:0031929TOR signalingIEA
GO:0051560mitochondrial calcium ion homeostasisIEA
GO:0060070canonical Wnt signaling pathwayIEA
GO:0090128regulation of synapse maturationIEA
GO:2000060positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic processIEA
Component
IDNameEvidence
GO:0005739mitochondrionIDA
GO:0005813centrosomeIDA
GO:0005874microtubuleIEA
GO:0014069postsynaptic densityIEA
GO:0030054cell junctionIEA
GO:0045211postsynaptic membraneIEA
Function
IDNameEvidence
GO:0005515protein bindingIPI
GeneCards DISC1
UniProt C4P0D0, C4P0A4, C4P0D1, C4P0A5, C4P098, C4P094, C4P0C4, C4P096, C4P0C8, C4P0D2, Q9NRI5, C4P0D3
Vega OTTHUMG00000037835
MIM 605210
Ensembl ENSG00000162946
HGNC 2888
HPRD 05553

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Interactant

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