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GNAI3 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 [Homo sapiens (human)]

RefSeq Accession Definition Service Stock Status Price *Turnaround time Order
NM_006496 Homo sapiens guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 (GNAI3), mRNA. GenEZ ORF Cloning In-stock $418.00 $369.00 10

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Gene Symbol GNAI3
Entrez Gene ID 2773
Full Name guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3
Synonyms 87U6, FLJ26559
Gene Type protein-coding
Organism Homo sapiens (human)



Summary Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling pathways. G proteins are composed of 3 units: alpha, beta and gamma. This gene encodes an alpha subunit and belongs to the G-alpha family. Mutation in this gene, resulting in a gly40-to-arg substitution, is associated with auriculocondylar syndrome, and shown to affect downstream targets in the G protein-coupled endothelin receptor pathway. [provided by RefSeq, Jun 2012].

MIM: 139370

mRNA Protein Product Sequence Price Select
NM_006496, 391224482 NP_006487, 5729850 guanine nucleotide-binding protein G(k) subunit alpha ORF Sequence $269.00
hsa04724Glutamatergic synapse
hsa04713Circadian entrainment
hsa04728Dopaminergic synapse
hsa04540Gap junction
hsa05032Morphine addiction
hsa04360Axon guidance
hsa04062Chemokine signaling pathway
hsa04727GABAergic synapse
hsa04723Retrograde endocannabinoid signaling
hsa04726Serotonergic synapse
hsa04670Leukocyte transendothelial migration
hsa04914Progesterone-mediated oocyte maturation
hsa04971Gastric acid secretion
hsa05142Chagas disease (American trypanosomiasis)
hsa04730Long-term depression
hsa05030Cocaine addiction
hsa04725Cholinergic synapse
hsa04530Tight junction
WP26Signal Transduction of S1P Receptor
WP536Calcium Regulation in the Cardiac Cell
WP35G Protein Signaling Pathways
WP2032TSH signaling pathway
Pathway Interaction Database
s1p_s1p2_pathwayS1P2 pathway
cxcr3pathwayCXCR3-mediated signaling events
s1p_meta_pathwaySphingosine 1-phosphate (S1P) pathway
s1p_s1p4_pathwayS1P4 pathway
s1p_s1p3_pathwayS1P3 pathway
erbb1_receptor_proximal_pathwayEGF receptor (ErbB1) signaling pathway
lysophospholipid_pathwayLPA receptor mediated events
s1p_s1p1_pathwayS1P1 pathway
s1p_s1p5_pathwayS1P5 pathway
REACT_15333Adenylate cyclase inhibitory pathway
REACT_13477Transmission across Chemical Synapses
REACT_19333G alpha (z) signalling events
REACT_15295Opioid Signalling
REACT_25199GABA receptor activation
REACT_19327G alpha (s) signalling events
REACT_19231G alpha (i) signalling events
REACT_13685Neuronal System
REACT_15526G-protein mediated events
REACT_15426PLC beta mediated events
REACT_111102Signal Transduction
REACT_798Platelet activation, signaling and aggregation
REACT_14797Signaling by GPCR
REACT_25330Activation of GABAB receptors
REACT_20524Signal amplification
REACT_15370Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
REACT_25031GABA B receptor activation
REACT_20653ADP signalling through P2Y purinoceptor 12
REACT_15457G-protein activation
REACT_19184GPCR downstream signaling
REACT_25282Inhibition of adenylate cyclase pathway
Homo sapiens (human)GNAI3NP_006487.1
Pan troglodytes (chimpanzee)GNAI3XP_513624.1
Macaca mulatta (Rhesus monkey)GNAI3XP_001091470.1
Canis lupus familiaris (dog)GNAI3XP_854614.3
Bos taurus (cattle)GNAI3NP_001029849.1
Mus musculus (house mouse)Gnai3NP_034436.1
Rattus norvegicus (Norway rat)Gnai3NP_037238.1
Gallus gallus (chicken)GNAI3NP_989580.1
Danio rerio (zebrafish)gnai3NP_001104720.1
GeneCards GNAI3
PDB 4G5R, 4G5O, 4G5S, 2IHB, 2V4Z, 2ODE
UniProt P08754, Q5TZX1
MIM 139370
Ensembl ENSG00000065135
HGNC 4387
HPRD 00765

GeneRIFs: Gene References Into Functions What's a GeneRIF?

General protein information

Preferred Names
guanine nucleotide-binding protein G(k) subunit alpha
guanine nucleotide-binding protein G(k) subunit alpha
g(i) alpha-3


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