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GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O [Homo sapiens (human)]


Clone ID RefSeq Accession Definition Vector Stock Status *Turnaround time Price Order
OHu13586 NM_020988 Homo sapiens guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O (GNAO1), transcript variant 1, mRNA. pcDNA3.1+-DYK In-stock 5-7 $99.00
OHu13628 NM_138736 Homo sapiens guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O (GNAO1), transcript variant 2, mRNA. pcDNA3.1+-DYK On-demand 7-9 $219.00
OHu13586C NM_020988 Homo sapiens guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O (GNAO1), transcript variant 1, mRNA. Customized vector In-stock 5-7 $149.00
OHu13628C NM_138736 Homo sapiens guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O (GNAO1), transcript variant 2, mRNA. Customized vector On-demand 7-9 $269.00

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Gene Symbol GNAO1
Entrez Gene ID 2775
Full Name guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
Synonyms EIEE17, G-ALPHA-o, GNAO
General protein information
Preferred Names
guanine nucleotide-binding protein G(o) subunit alpha
Names
guanine nucleotide-binding protein G(o) subunit alpha
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

16

16q13

Summary
Disorder

MIM: 139311

mRNA Protein Product Sequence Price Select
NM_020988, 162461666 NP_066268, 10567816 guanine nucleotide-binding protein G(o) subunit alpha isoform a ORF Sequence $269.00
NM_138736, 162461737 NP_620073, 162461738 guanine nucleotide-binding protein G(o) subunit alpha isoform b ORF Sequence $400.00
KEGG
hsa04730Long-term depression
hsa04916Melanogenesis
hsa05142Chagas disease (American trypanosomiasis)
hsa05145Toxoplasmosis
hsa04724Glutamatergic synapse
hsa04725Cholinergic synapse
hsa04727GABAergic synapse
hsa04728Dopaminergic synapse
hsa04726Serotonergic synapse
hsa04723Retrograde endocannabinoid signaling
hsa04713Circadian entrainment
hsa04915Estrogen signaling pathway
hsa05034Alcoholism
hsa05032Morphine addiction
hsa04921Oxytocin signaling pathway
hsa04015Rap1 signaling pathway
WikiPathways
WP35G Protein Signaling Pathways
WP536Calcium Regulation in the Cardiac Cell
WP2032TSH signaling pathway
WP2355Corticotropin-releasing hormone
Pathway Interaction Database
lysophospholipid_pathwayLPA receptor mediated events
s1p_meta_pathwaySphingosine 1-phosphate (S1P) pathway
s1p_s1p1_pathwayS1P1 pathway
s1p_s1p5_pathwayS1P5 pathway
s1p_s1p3_pathwayS1P3 pathway
s1p_s1p2_pathwayS1P2 pathway
s1p_s1p4_pathwayS1P4 pathway
Reactome
REACT_14797Signaling by GPCR
REACT_15295Opioid Signalling
REACT_15526G-protein mediated events
REACT_15426PLC beta mediated events
REACT_11045Signaling by Wnt
REACT_15457G-protein activation
REACT_111102Signal Transduction
REACT_172761Ca2+ pathway
REACT_172694beta-catenin independent WNT signaling
Homo sapiens (human)GNAO1NP_066268.1
Pan troglodytes (chimpanzee)GNAO1XP_510976.3
Macaca mulatta (Rhesus monkey)GNAO1XP_001096035.2
Canis lupus familiaris (dog)GNAO1XP_005617599.1
Bos taurus (cattle)GNAO1NP_776750.1
Mus musculus (house mouse)Gnao1NP_034438.1
Rattus norvegicus (Norway rat)Gnao1NP_059023.1
Gallus gallus (chicken)GNAO1NP_001264479.1
Danio rerio (zebrafish)gnao1aNP_957081.1
Drosophila melanogaster (fruit fly)G-oalpha47ANP_724934.1
Caenorhabditis elegansgoa-1NP_492108.1
Xenopus (Silurana) tropicalis (western clawed frog)gnao1NP_001016995.1
Process
IDNameEvidence
GO:0006184GTP catabolic processIEA
GO:0006936muscle contractionTAS
GO:0007188adenylate cyclase-modulating G-protein coupled receptor signaling pathwayIBA
GO:0007212dopamine receptor signaling pathwayIBA
GO:0007568agingIEA
GO:0007626locomotory behaviorIEA
GO:0008016regulation of heart contractionIEA
GO:0030900forebrain developmentIEA
GO:0031175neuron projection developmentIEA
GO:0034097response to cytokineIEA
GO:0042493response to drugIEA
GO:0042542response to hydrogen peroxideIEA
GO:0043278response to morphineIEA
GO:0043547positive regulation of GTPase activityIEA
GO:0051926negative regulation of calcium ion transportIEA
Component
IDNameEvidence
GO:0005834heterotrimeric G-protein complexIBA
GO:0005886plasma membraneTAS
GO:0043005neuron projectionIEA
Function
IDNameEvidence
GO:0003924GTPase activityIBA
GO:0004871signal transducer activityIBA
GO:0005525GTP bindingIEA
GO:0031683G-protein beta/gamma-subunit complex bindingIBA
GO:0031821G-protein coupled serotonin receptor bindingIBA
GO:0031852mu-type opioid receptor bindingIBA
GO:0032794GTPase activating protein bindingIEA
GO:0046872metal ion bindingIEA
GO:0051430corticotropin-releasing hormone receptor 1 bindingIBA
GeneCards GNAO1
UniProt Q8N6I9, B3KP89, P09471, Q6AWC5
Vega OTTHUMG00000133241
MIM 139311
Ensembl ENSG00000087258
HGNC 4389
HPRD 00757

GeneRIFs: Gene References Into Functions What's a GeneRIF?

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