Sequence in raw or FASTA format:
COL1A1 collagen, type I, alpha 1 [Bos taurus (cattle)]
| Gene Symbol | COL1A1 |
| Entrez Gene ID | 282187 |
| Full Name | collagen, type I, alpha 1 |
| Synonyms | MGC128258 |
| Gene Type | protein-coding |
| Organism | Bos taurus (cattle) |
| Genome |
19 |
| Summary | |
| Disorder | MIM: |
| mRNA | NM_001034039, 77404251 |
| Protein | NP_001029211, 77404252 |
| Product | collagen alpha-1(I) chain precursor |
| RefSeq Status | PROVISIONAL |
| bta05146 | Amoebiasis |
| bta04512 | ECM-receptor interaction |
| bta04974 | Protein digestion and absorption |
| bta04510 | Focal adhesion |
Reactome
| 1163887 | Collagen adhesion via alpha 2 beta 1 glycoprotein |
| 1164280 | NCAM1 interactions |
| 1163878 | Hemostasis |
| 1163888 | vWF interaction with collagen |
| 1163886 | Integrin cell surface interactions |
| 1163778 | Signaling by PDGF |
| 1163877 | Formation of Platelet plug |
| 1163780 | NCAM signaling for neurite out-growth |
| 1163875 | Collagen adhesion via Gp IV |
| 1163876 | Platelet Adhesion to exposed collagen |
| 1163781 | Axon guidance |
| Homo sapiens (human) | COL1A1 | NP_000079.2 |
| Pan troglodytes (chimpanzee) | COL1A1 | XP_001169386.1 |
| Canis lupus familiaris (dog) | COL1A1 | NP_001003090.1 |
| Bos taurus (cattle) | COL1A1 | NP_001029211.1 |
| Mus musculus (house mouse) | Col1a1 | NP_031768.2 |
| Rattus norvegicus (Norway rat) | Col1a1 | XP_213440.1 |
| Danio rerio (zebrafish) | col1a1a | NP_954684.1 |
| ID | Name | Evidence |
| GO:0001568 | blood vessel development | IEA |
| GO:0001649 | osteoblast differentiation | IEA |
| GO:0001957 | intramembranous ossification | IEA |
| GO:0001958 | endochondral ossification | IEA |
| GO:0007601 | visual perception | IEA |
| GO:0007605 | sensory perception of sound | IEA |
| GO:0010718 | positive regulation of epithelial to mesenchymal transition | IEA |
| GO:0010812 | negative regulation of cell-substrate adhesion | IEA |
| GO:0015031 | protein transport | IEA |
| GO:0030199 | collagen fibril organization | IEA |
| GO:0030335 | positive regulation of cell migration | IEA |
| GO:0032964 | collagen biosynthetic process | IEA |
| GO:0034504 | protein localization to nucleus | IEA |
| GO:0034505 | tooth mineralization | IEA |
| GO:0043589 | skin morphogenesis | IEA |
| GO:0048706 | embryonic skeletal system development | IEA |
| GO:0060325 | face morphogenesis | IEA |
| GO:0060346 | bone trabecula formation | IEA |
| GO:0060351 | cartilage development involved in endochondral bone morphogenesis | IEA |
| GO:0070208 | protein heterotrimerization | IEA |
| GO:0090263 | positive regulation of canonical Wnt receptor signaling pathway | IEA |
Component
| ID | Name | Evidence |
| GO:0005576 | extracellular region | IEA |
| GO:0005581 | collagen | IEA |
| GO:0005584 | collagen type I | IEA |
| GO:0005615 | extracellular space | IEA |
| GO:0005737 | cytoplasm | IEA |
Function
| ID | Name | Evidence |
| GO:0005201 | extracellular matrix structural constituent | IEA |
| GO:0005515 | protein binding | IPI |
| GO:0042802 | identical protein binding | IEA |
| GO:0048407 | platelet-derived growth factor binding | IEA |
| GeneCards | COL1A1 |
| UniProt | P02453 |
| Ensembl | ENSBTAG00000013103 |
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