B4GALNT3 beta-1,4-N-acetyl-galactosaminyl transferase 3 [Homo sapiens (human)]
| Gene Symbol | B4GALNT3 |
| Entrez Gene ID | 283358 |
| Full Name | beta-1,4-N-acetyl-galactosaminyl transferase 3 |
| Synonyms | FLJ16224, FLJ40362 |
| Gene Type | protein-coding |
| Organism | Homo sapiens (human) |
| Genome |
12 12p13.33 |
| Summary | B4GALNT3 transfers N-acetylgalactosamine (GalNAc) onto glucosyl residues to form N,N-prime-diacetyllactosediamine (LacdiNAc, or LDN), a unique terminal structure of cell surface N-glycans (Ikehara et al., 2006 [PubMed 16728562]).[supplied by OMIM]. |
| Disorder | MIM: 612220 |
| mRNA | NM_173593, 71043499 |
| Protein | NP_775864, 71043500 |
| Product | N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase 2 |
| RefSeq Status | VALIDATED |
| Homo sapiens (human) | B4GALNT3 | NP_775864.3 |
| Pan troglodytes (chimpanzee) | B4GALNT3 | XP_508918.2 |
| Canis lupus familiaris (dog) | B4GALNT3 | XP_543878.2 |
| Mus musculus (house mouse) | B4galnt3 | NP_942585.1 |
| Rattus norvegicus (Norway rat) | B4galnt3 | XP_575655.2 |
| Gallus gallus (chicken) | B4GALNT3 | XP_416381.2 |
| ID | Name | Evidence |
| GO:0005794 | Golgi apparatus | IEA |
| GO:0016020 | membrane | IEA |
| GO:0016021 | integral to membrane | IEA |
| GO:0032580 | Golgi cisterna membrane | IEA |
Function
| ID | Name | Evidence |
| GO:0008376 | acetylgalactosaminyltransferase activity | IDA |
| GO:0016740 | transferase activity | IEA |
| GO:0033842 | N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity | IEA |
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