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Sequence in raw or FASTA format:

Database:

Blast Method:

 
 


KANSL1 KAT8 regulatory NSL complex subunit 1 [Homo sapiens (human)]


RefSeq Accession Definition Service Stock Status Price *Turnaround time Order
NM_001193465 Homo sapiens KAT8 regulatory NSL complex subunit 1 (KANSL1), transcript variant 3, mRNA. GenEZ ORF Cloning On-demand $1699.00 25
NM_001193466 Homo sapiens KAT8 regulatory NSL complex subunit 1 (KANSL1), transcript variant 1, mRNA. GenEZ ORF Cloning In-stock $1198.00 $1149.00 16
NM_015443 Homo sapiens KAT8 regulatory NSL complex subunit 1 (KANSL1), transcript variant 2, mRNA. GenEZ ORF Cloning In-stock $1198.00 $1149.00 16
XM_005257232 PREDICTED: Homo sapiens KAT8 regulatory NSL complex subunit 1 (KANSL1), transcript variant X1, mRNA. GenEZ ORF Cloning On-demand $1699.00 25
XM_005257233 PREDICTED: Homo sapiens KAT8 regulatory NSL complex subunit 1 (KANSL1), transcript variant X2, mRNA. GenEZ ORF Cloning On-demand $1699.00 25
XM_005257234 PREDICTED: Homo sapiens KAT8 regulatory NSL complex subunit 1 (KANSL1), transcript variant X3, mRNA. GenEZ ORF Cloning On-demand $1699.00 25
XM_005257235 PREDICTED: Homo sapiens KAT8 regulatory NSL complex subunit 1 (KANSL1), transcript variant X4, mRNA. GenEZ ORF Cloning On-demand $1699.00 25
XM_005275644 PREDICTED: Homo sapiens KAT8 regulatory NSL complex subunit 1 (KANSL1), transcript variant X1, mRNA. GenEZ ORF Cloning On-demand $1699.00 25
XM_005275645 PREDICTED: Homo sapiens KAT8 regulatory NSL complex subunit 1 (KANSL1), transcript variant X2, mRNA. GenEZ ORF Cloning On-demand $1699.00 25
XM_006721823 PREDICTED: Homo sapiens KAT8 regulatory NSL complex subunit 1 (KANSL1), transcript variant X1, mRNA. GenEZ ORF Cloning On-demand $1699.00 25
XM_006721824 PREDICTED: Homo sapiens KAT8 regulatory NSL complex subunit 1 (KANSL1), transcript variant X2, mRNA. GenEZ ORF Cloning On-demand $1699.00 25
XM_006721825 PREDICTED: Homo sapiens KAT8 regulatory NSL complex subunit 1 (KANSL1), transcript variant X3, mRNA. GenEZ ORF Cloning On-demand $1699.00 25
XM_006721826 PREDICTED: Homo sapiens KAT8 regulatory NSL complex subunit 1 (KANSL1), transcript variant X4, mRNA. GenEZ ORF Cloning On-demand $1699.00 25
XM_006725263 PREDICTED: Homo sapiens KAT8 regulatory NSL complex subunit 1 (KANSL1), transcript variant X3, mRNA. GenEZ ORF Cloning On-demand $1699.00 25
XM_006725264 PREDICTED: Homo sapiens KAT8 regulatory NSL complex subunit 1 (KANSL1), transcript variant X4, mRNA. GenEZ ORF Cloning On-demand $1699.00 25

*Business Day

Related Services

Gene Symbol KANSL1
Entrez Gene ID 284058
Full Name KAT8 regulatory NSL complex subunit 1
Synonyms CENP-36, KDVS, KIAA1267, MSL1v1, NSL1, hMSL1v1
General protein information
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

17

17q21.31

Summary This gene encodes a nuclear protein that is a subunit of two protein complexes involved with histone acetylation, the MLL1 complex and the NSL1 complex. The corresponding protein in Drosophila interacts with K(lysine) acetyltransferase 8, which is also a subunit of both the MLL1 and NSL1 complexes. [provided by RefSeq, Jun 2012].
Disorder

MIM: 612452

mRNA Protein Product Sequence Price Select
NM_001193465, 301500642 NP_001180394, 301500643 KAT8 regulatory NSL complex subunit 1 isoform 2 ORF Sequence $1500.00
NM_001193466, 301500644 NP_001180395, 301500645 KAT8 regulatory NSL complex subunit 1 isoform 1 ORF Sequence $999.00
NM_015443, 301500641 NP_056258, 32698714 KAT8 regulatory NSL complex subunit 1 isoform 1 ORF Sequence $999.00
XM_005257232, 578841167 XP_005257289, 578841168 KAT8 regulatory NSL complex subunit 1 isoform X1 ORF Sequence $1500.00
XM_005257233, 578841169 XP_005257290, 578841170 KAT8 regulatory NSL complex subunit 1 isoform X2 ORF Sequence $1500.00
XM_005257234, 578841171 XP_005257291, 578841172 KAT8 regulatory NSL complex subunit 1 isoform X3 ORF Sequence $1500.00
XM_005257235, 578841173 XP_005257292, 578841174 KAT8 regulatory NSL complex subunit 1 isoform X4 ORF Sequence $1500.00
XM_005275644, 530429793 XP_005275701, 530429794 KAT8 regulatory NSL complex subunit 1 isoform X1 ORF Sequence $1500.00
XM_005275645, 530429795 XP_005275702, 530429796 KAT8 regulatory NSL complex subunit 1 isoform X2 ORF Sequence $1500.00
XM_006721823, 578830732 XP_006721886, 578830733 KAT8 regulatory NSL complex subunit 1 isoform X1 ORF Sequence $1500.00
XM_006721824, 578830734 XP_006721887, 578830735 KAT8 regulatory NSL complex subunit 1 isoform X2 ORF Sequence $1500.00
XM_006721825, 578830736 XP_006721888, 578830737 KAT8 regulatory NSL complex subunit 1 isoform X3 ORF Sequence $1500.00
XM_006721826, 578830738 XP_006721889, 578830739 KAT8 regulatory NSL complex subunit 1 isoform X4 ORF Sequence $1500.00
XM_006725263, 578840178 XP_006725326, 578840179 KAT8 regulatory NSL complex subunit 1 isoform X3 ORF Sequence $1500.00
XM_006725264, 578840180 XP_006725327, 578840181 KAT8 regulatory NSL complex subunit 1 isoform X4 ORF Sequence $1500.00
Reactome
REACT_172633Chromatin modifying enzymes
REACT_172610HATs acetylate histones
REACT_172623Chromatin organization
Homo sapiens (human)KANSL1NP_001180395.1
Pan troglodytes (chimpanzee)KANSL1XP_001137659.2
Macaca mulatta (Rhesus monkey)KANSL1XP_001115950.1
Canis lupus familiaris (dog)KANSL1XP_003435236.1
Bos taurus (cattle)KANSL1XP_003587505.1
Mus musculus (house mouse)Kansl1NP_001074514.1
Rattus norvegicus (Norway rat)Kansl1XP_006247613.1
Gallus gallus (chicken)KANSL1XP_003642834.2
Danio rerio (zebrafish)LOC567884XP_696283.4
Xenopus (Silurana) tropicalis (western clawed frog)LOC100485168XP_002935569.2
Process
IDNameEvidence
GO:0006325chromatin organizationTAS
GO:0043981histone H4-K5 acetylationIDA
GO:0043982histone H4-K8 acetylationIDA
GO:0043984histone H4-K16 acetylationIDA
Component
IDNameEvidence
GO:0000123histone acetyltransferase complexIDA
GO:0005634nucleusIDA
GO:0005654nucleoplasmTAS
GO:0071339MLL1 complexIDA
Function
IDNameEvidence
GO:0005515protein bindingIPI
GO:0043995histone acetyltransferase activity (H4-K5 specific)IDA
GO:0043996histone acetyltransferase activity (H4-K8 specific)IDA
GO:0046972histone acetyltransferase activity (H4-K16 specific)IDA
GeneCards KANSL1
UniProt Q7Z3B3
Vega OTTHUMG00000178026
MIM 612452
Ensembl ENSG00000120071
HGNC 24565
HPRD 11254

What is the normal function of the KANSL1 gene?

The KANSL1 gene provides instructions for making a member (subunit) of a group of interacting proteins called the KAT8 regulatory NSL complex. This complex is categorized as a histone acetyltransferase (HAT) complex. It helps regulate gene activity (expression) by modifying chromatin, the complex of DNA and protein that packages DNA into chromosomes.

The protein produced from the KANSL1 gene is found in most organs and tissues of the body before birth and throughout life. By its involvement in controlling the activity of other genes, this protein plays an important role in the development and function of many parts of the body.

Interactant

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