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SLC25A4 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4 [Homo sapiens (human)]

RefSeq Accession Definition Service Stock Status Price *Turnaround time Order
NM_001151 Homo sapiens solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4 (SLC25A4), nuclear gene encoding mitochondrial protein, mRNA. GenEZ ORF Cloning In-stock $348.00 $299.00 10

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Gene Symbol SLC25A4
Entrez Gene ID 291
Full Name solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4
Synonyms AAC1, ANT, ANT1, PEO2, PEO3, T1
Gene Type protein-coding
Organism Homo sapiens (human)



Summary This gene is a member of the mitochondrial carrier subfamily of solute carrier protein genes. The product of this gene functions as a gated pore that translocates ADP from the mitochondrial matrix into the cytoplasm. The protein forms a homodimer embedded in the inner mitochondria membrane. Mutations in this gene have been shown to result in autosomal dominant progressive external opthalmoplegia and familial hypertrophic cardiomyopathy. [provided by RefSeq, Sep 2009].

MIM: 103220

Progressive external ophthalmoplegia with mitochondrial DNA

mRNA Protein Product Sequence Price Select
NM_001151, 258547122 NP_001142, 55749577 ADP/ATP translocase 1 ORF Sequence $199.00
hsa05012Parkinson's disease
hsa04020Calcium signaling pathway
hsa05016Huntington's disease
hsa05166HTLV-I infection
WP2267Synaptic Vesicle Pathway
WP111Electron Transport Chain
WP706SIDS Susceptibility Pathways
REACT_1505Integration of energy metabolism
REACT_6757Interactions of Vpr with host cellular proteins
REACT_118595Mitochondrial Protein Import
REACT_6288Host Interactions of HIV factors
REACT_8016Vpr-mediated induction of apoptosis by mitochondrial outer membrane permeabilization
REACT_17015Metabolism of proteins
REACT_6185HIV Infection
REACT_18325Regulation of Insulin Secretion
Homo sapiens (human)SLC25A4NP_001142.2
Pan troglodytes (chimpanzee)SLC25A4XP_517556.3
Macaca mulatta (Rhesus monkey)SLC25A4XP_001084544.1
Canis lupus familiaris (dog)SLC25A4XP_532844.2
Bos taurus (cattle)SLC25A4NP_777083.1
Mus musculus (house mouse)Slc25a4NP_031476.3
Rattus norvegicus (Norway rat)Slc25a4NP_445967.1
Gallus gallus (chicken)SLC25A4NP_001006443.1
Danio rerio (zebrafish)slc25a4NP_999867.1
Drosophila melanogaster (fruit fly)sesBNP_727448.1
GeneCards SLC25A4
UniProt P12235
MIM 103220
Ensembl ENSG00000151729
HGNC 10990
HPRD 00058

GeneRIFs: Gene References Into Functions What's a GeneRIF?

General protein information

Preferred Names
ADP/ATP translocase 1
ADP/ATP translocase 1
ADP,ATP carrier protein 1
solute carrier family 25 member 4
heart/skeletal muscle ATP/ADP translocator
ADP,ATP carrier protein, heart/skeletal muscle
adenine nucleotide translocator 1 (skeletal muscle)


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