Sequence in raw or FASTA format:
ntrk1 neurotrophic tyrosine kinase, receptor, type 1 [Danio rerio (zebrafish)]
| Gene Symbol | ntrk1 |
| Entrez Gene ID | 30546 |
| Full Name | neurotrophic tyrosine kinase, receptor, type 1 |
| Synonyms | trk, trka |
| Gene Type | protein-coding |
| Organism | Danio rerio (zebrafish) |
| Genome |
16 |
| Summary | |
| Disorder | MIM: |
| mRNA | XM_692154, 292622630 |
| Protein | XP_697246, 292622631 |
| Product | high affinity nerve growth factor receptor |
| RefSeq Status | MODEL |
| dre04144 | Endocytosis |
| dre04210 | Apoptosis |
| dre04010 | MAPK signaling pathway |
WikiPathways
| WP1337 | MAPK signaling pathway |
Reactome
| 1330370 | Signalling to p38 via RIT and RIN |
| 1330582 | TRKA activation by NGF |
| 1330273 | Signalling by NGF |
| 1330641 | NGF-independant TRKA activation |
| 1330288 | Signalling to RAS |
| 1330377 | ARMS-mediated activation |
| 1330376 | Prolonged ERK activation events |
| 1330583 | Activation of TRKA receptors |
| 1330375 | Frs2-mediated activation |
| 1330729 | Signalling to STAT3 |
| 1330636 | Retrograde neurotrophin signalling |
| 1330717 | PI3K/AKT signalling |
| 1330272 | NGF signalling via TRKA from the plasma membrane |
| 1330289 | Signalling to ERKs |
| Homo sapiens (human) | NTRK1 | NP_002520.2 |
| Pan troglodytes (chimpanzee) | NTRK1 | XP_001145942.1 |
| Canis lupus familiaris (dog) | NTRK1 | XP_547525.2 |
| Bos taurus (cattle) | NTRK1 | XP_613650.3 |
| Mus musculus (house mouse) | Ntrk1 | XP_283871.1 |
| Rattus norvegicus (Norway rat) | Ntrk1 | NP_067600.1 |
| Gallus gallus (chicken) | NTRK1 | NP_990709.1 |
| Danio rerio (zebrafish) | ntrk1 | XP_697246.4 |
| ID | Name | Evidence |
| GO:0006468 | protein phosphorylation | IEA |
| GO:0007169 | transmembrane receptor protein tyrosine kinase signaling pathway | IEA |
| GO:0016310 | phosphorylation | IEA |
Component
| ID | Name | Evidence |
| GO:0005887 | integral to plasma membrane | IEA |
| GO:0016020 | membrane | IEA |
| GO:0016021 | integral to membrane | IEA |
Function
| ID | Name | Evidence |
| GO:0000166 | nucleotide binding | IEA |
| GO:0004672 | protein kinase activity | IEA |
| GO:0004713 | protein tyrosine kinase activity | IEA |
| GO:0004714 | transmembrane receptor protein tyrosine kinase activity | IEA |
| GO:0004872 | receptor activity | IEA |
| GO:0005030 | neurotrophin receptor activity | IEA |
| GO:0005524 | ATP binding | IEA |
| GO:0016301 | kinase activity | IEA |
| GO:0016740 | transferase activity | IEA |
| GO:0016772 | transferase activity, transferring phosphorus-containing groups | IEA |
| GeneCards | ntrk1 |
| UniProt | B3DGZ3 |
| Ensembl | ENSDARG00000004586 |
| ZFIN | ZDB |
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